Thiophenesulfonamide herbicides

ABSTRACT

Thiophenesulfonamides of the formula ##STR1## are useful as herbicides.

RELATED APPLICATION

This application is a continuation-in-part of copending application U.S. Ser. No. 852,739, filed Apr. 21, 1986, now abandoned which is a continution-in-part of U.S. Ser. No. 739,074, filed May 29, 1985, now abandoned.

TECHNICAL FIELD

This invention relates to certain novel thiophenesulfonamide compounds, to compositions containing such compounds, and to a method of use of such compositions to control the growth of undesired vegetation.

BACKGROUND OF THE INVENTION

The presence of undesired vegetation causes substantial damage to agricultural products which helps satisfy man's basic food and fiber needs. The current population explosion and concomitant world food and fiber shortage demand improved productivity in agricultural efforts since virtually all the readily available, relatively fertile cropland in developed countries has already been placed in use [Science 214, 1087, 1089 (1981)]. Preventing or minimizing loss of a portion of such valuable crops, by inhibiting the growth or killing undesired competing vegetation which is potentially damaging to crop yields [Science 215, 324 (1982)], is a significant approach to improving agricultural efficiency.

A wide variety of materials, commonly referred to as herbicides, useful for controlling the growth of undesired vegetation (by killing or inhibiting) is available. There still exists a need, however, for effective herbicides which destroy or control weeds while not significantly damaging useful crops. Efficient production on large acreage requires the extensive use of herbicides, with approximately 625 million lb. of herbicides used by American farmers in 1981 [Chemical Week, July 7, 182, p. 36]. At the present time, no existing product provides all features deemed advantageous. Greater persistence, less soil residual, reduced application rates, reduced soil binding, greater selectivity or safety margin between weed control and crop injury, and less dependence on rainfall for activation are currently desirable features for herbicides.

U.S. Pat. No. 4,127,405 and U.S. Pat. No. 4,169,719 disclose herbicidal thiophenesulfonamides, wherein the thiophene ring may be optionally substituted with CH₃, Cl or Br.

U.S. Pat. No. 4,398,939 discloses herbicidal thiophenesulfonamides, wherein the thiophene ring is substituted with substituent groups selected from C₁ -C₄ alkyl, C₃ alkenyl, OCH₃, NO₂, Cl, Br, SO₂ N(C₁ -C₃ alkyl)₂ or SO₂ N(OCH₃)CH₃.

U.S. Pat. No. 4,481,029 discloses herbicidal thiophenesulfonamides, wherein the thiophene ring is substituted with carboxylic acid, carboxylic ester and alkylcarbonyl groups or derivatives thereof.

U.S. Pat. No. 4,441,910 discloses herbicidal thiophenesulfonamides, wherein the thiophene ring is substituted with the group represented by R₆ S(O)_(n) wherein R₆ is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, cyclopentyl or cyclopropylmethyl.

U.S. Pat. No. 4,518,776 discloses, in part, a process for the preparation of compounds of formula ##STR2## wherein G is ##STR3## R₁ is H, C₁ -C₄ alkyl, halogen, NO₂, CN, NH₂, S(O)_(n) C₁ -C₄ alkyl, SO₂ C₁ -C₄ alkoxy, SO₂ -di-C₁ -C₄ alkylamino, CHO, CONH₂, DC₃ -C₅ alkynyl, CODC₃ -C₅ alkynyl, DC₁ -C₄ alkyl, DC₃ -C₅ alkenyl, COC₁ -C₄ alkyl, CODC₁ -C₄ alkyl or CODC₃ -C₅ alkenyl;

n is 1 or 2;

D is O, S, NH or NC₁ -C₄ alkyl;

R₂ is H, halogen, CF₃, NO₂, C₁ -C₄ alkyl or C₁ -C₄ alkoxy;

A is O, S, NR₅ or --C═N--;

X is C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₁ -C₄ alkoxy, C₁ -C₄ alkylthio, C₁ -C₄ haloalkoxy, C₁ -C₄ alkylamino or di-C₁ -C₄ alkylamino;

Y is C₁ -C₄ alkyl, C₁ -C₄ alkoxy or C₁ -C₄ haloalkoxy; and

Z is CH or N.

EP-A-No. 101,670 discloses, in part, a process for the preparation of compounds of formula ##STR4## wherein G is ##STR5## R₁ is H, halogen, NO₂, QC₁ -C₄ alkyl, C₁ -C₄ alkyl, CF₃, SO₂ -di-C₁ -C₄ alkylamino, COQC₃ -C₄ alkynyl, COQC₁ -C₄ alkyl or COQC₃ -C₅ alkenyl optionally substituted by halogen, CN, C₁ -C₄ alkoxy or C₁ -C₄ alkyltio;

Q is O, S(O)_(n), NH or N(C₁ -C₄ alkyl);

n is 0, 1 or 2;

R₂ is H, halogen, CF₃, NO₂, C₁ -C₄ alkyl or C₁ -C₄ alkoxy;

A is O, S, NR₅ or --C═N--;

X is C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₁ -C₄ alkoxy, C₁ -C₄ alkylthio, C₁ -C₄ haloalkoxy, C₁ -C₄ alkylamino or di-C₁ -C₄ alkylamino;

Y is C₁ -C₄ alkyl, C₁ -C₄ alkoxy or C₁ -C₄ haloalkoxy; and

Z is CH or N.

U.S. Pat. No. 4,521,597 discloses, in part, a process for the preparation of compounds of formula ##STR6## wherein A is ##STR7## R₃ is H, halogen, NO₂, OCH₃ or CF₃ ; R₅ is H, F, Cl, Br, NO₂, C₁ -C₅ alkyl, C₁ -C₅ alkoxy, CF₃, S(O)_(m) C₁ -C₅ alkyl, COR₇ or SO₂ NR₈ R₉ ;

Y is O, S or C(R₆)═N;

R_(a) is H, halogen, C₁ -C₅ alkyl, C₁ -C₅ haloalkyl, C₁ -C₅ alkoxy, C.sub. -C₅ haloalkoxy, C₁ -C₅ alkylthio, C₂ -C₁₀ alkoxyalkyl or C₂ -C₁₀ alkoxyalkoxy;

R_(b) is the same as R_(a) or NR_(c) R_(d) ; and

E is CH or N.

U.S. Pat. No. 4,549,898 discloses herbicidal sulfonylureas of formula ##STR8## wherein X is O, S, NR₄ or C(R₅)═N;

Y is O or S;

Z is O or S;

E is N or CH;

R₁ is H, C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkoxy, C₁ -C₄ alkoxy, halogen, C₁ -C₄ alkylthio, NR₆ R₇ or alkoxyalkyl containing not more than 4 carbon atoms;

R₂ is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, NO₂, C₁ -C₃ alkoxy, C(W)R₈, SO₂ NR₆ R₇, S(O)_(n) -C₁ -C₃ alkyl or COR₉ ;

R₃ is H, halogen, C₁ -C₃ alkyl, OCH₃ or CF₃ ;

R₅ is H, NO₂, F, Cl, Br, CH₃, CF₃, S(O)_(n) C₁ -C₃ alkyl, COC₁ -C₄ alkoxy or C₁ -C₃ alkoxy;

R₆ is H, C₁ -C₆ alkyl, C₁ -C₄ cyanoalkyl, methoxy or ethoxy; and

R₇ is H, C₁ -C₆ alkyl or C₃ -C₆ alkenyl.

EP-A-No. 146,263 published June 26, 1985, discloses herbicidal thiophenesulfonamides represented by the following generic formulae. ##STR9##

EP-A-No. 165,753 published Dec. 27, 1985, discloses herbicidal thiophenesulfonamides substituted with 5- and 6-membered heterocyclic rings.

EP-A-No. 177,163 published Apr. 9, 1986 discloses herbicidal thiophenesulfonamides substituted with acetal and ketal groups.

U.S. Pat. No. 4,421,550 discloses in part herbicidal thiophenesulfonamides of the formula ##STR10## wherein R₁₇ is H, F, Cl, Br, CH₃ or OCH₃ ; and

R₁₈ is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, F, Cl, Br, NO₂, CO₂ R₁₀, SO₂ NR₁₀ R₁₁, SO₂ N(OCH₃)CH₃ or S(O)_(n) R₁₃.

EP-A-No. 84,224 published July 27, 1983 discloses, in part, herbicidal thiophenesulfonamides of the formula ##STR11## wherein R₁₇ is H, F, Cl, Br, CH₃ or OCH₃ ; and

R₁₈ is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, F, Cl, Br, NO₂, CO₂ R₉, SO₂ NR₁₀ R₁₁, SO₂ N(OCH₃)CH₃ or S(O)_(n) R₁₃.

SUMMARY OF THE INVENTION

This application pertains to novel compounds of Formula I, agriculturally suitable compositions containing them and their method-of-use as preemergent and/or postemergent herbicides or plant growth regulants. ##STR12## wherein L is ##STR13## R is H or CH₃ ; W is O or S;

R₁ is R₁ ' or R₁ ";

R_(x) is H or halogen;

R₁ ' is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, nitro, C₁ -C₃ alkoxy, CN, C₁ -C₃ haloalkoxy or C₁ -C₃ haloalkylthio;

R₁ " is SO₂ NR_(a) R_(b), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, CO₂ R_(c) or C(O)NR_(g) R_(h) ;

R_(a) is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy, ethoxy or C₃ -C₄ alkenyl;

R_(b) is H or C₁ -C₃ alkyl; or

R_(a) and R_(b) may be taken together to form (CH₂)₃, (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ;

R_(c) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₃ cyanoalkyl, cyclopropylmethyl or C₂ -C₄ alkoxyalkyl;

R_(g) is H or C₁ -C₃ alkyl;

R_(h) is C₁ -C₃ alkyl;

Q is Q₁ or Q₂ ;

Q₁ is ER₂, NR₃ R₄, ##STR14## OSO₂ R₇, C₁ -C₄ haloalkyl, CN, SO₂ NHR₂₁, ##STR15## SO₂ NR₂₂ NR₂₃ R₂₄ or C₁ -C₄ alkyl substituted with R₈ ;

E is O, S, SO or SO₂ ;

W₁ is O or S;

J is O, S, NH, NCH₃, CH₂ or a single bond;

Q₂ is SO₂ NH₂, SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, halogen, CHO or CR_(p) ═NOR_(q) ;

R_(i) is C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy, ethoxy or C₃ -C₄ alkenyl;

R_(j) is C₁ -C₃ alkyl or

R_(i) and R_(j) may be taken together to form (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ;

R_(k) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₃ cyanoalkyl, cyclopropylmethyl or C₂ -C₄ alkoxyalkyl;

R_(m) is H or C₁ -C₃ alkyl;

R_(n) is C₁ -C₃ alkyl;

R_(p) is H, C.sub. -C₄ alkyl or C₁ -C₄ haloalkyl;

R_(q) is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl;

R₂ is C₁ -C₆ alkyl substituted with R₈, C₂ -C₆ alkenyl substituted with R₈, C₃ -C₆ alkynyl, C₃ -C₆ alkynyl substituted with R₈, C₁ -C₆ haloalkyl, C₂ -C₆ haloalkenyl or C₃ -C₆ haloalkynyl;

R₃ is C₁ -C₄ alkyl;

R₄ is H or C₁ -C₄ alkyl; or

R₃ and R₄ may be taken together to form (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ;

R₅ and R₆ are independently C₁ -C₂ alkyl, C₁ -C₂ alkoxy, C₁ -C₂ alkylthio, C₁ -C₂ alkylamino or di(C₁ -C₂ alkyl)amino;

R₇ is C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₃ -C₄ alkenyl, C₃ -C₄ haloalkenyl, C₃ -C₄ alkynyl, C₃ 14 C₄ haloalkynyl or NR₁₉ R₂₀ ;

R₈ is OR₉, S(O)_(n) R₁₀, CO₂ R₁₀, SO₂ NR₁₁ R₁₂, NR₁₁ R₁₂, CONR₁₁ R₁₂, C(O)R₁₃, ##STR16## CN, SCN, SH, NO₂ or N₃ ; R₉ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₁ -C₄ haloalkyl, C₃ -C₄ haloalkenyl, C₃ -C₄ haloalkynyl, C₂ -C₄ alkylcarbonyl, C₁ -C₄ alkylsulfonyl, C₂ -C₄ alkoxyalkyl, C₂ -C₄ alkylthioalkyl or C₂ -C₄ cyanoalkyl;

R₁₀ is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₁ -C₄ haloalkyl, C₃ -C₄ haloalkenyl, C₃ -C₄ haloalkynyl, C₂ -C₄ alkoxyalkyl, C₂ -C₄ alkylthioalkyl or C₂ -C₄ cyanoalkyl;

R₁₁ is H or C₁ -C₃ alkyl;

R₁₂ is H, C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₃ -C₆ cycloalkyl, C₂ -C₄ alkoxyalkyl, C₂ -C₄ alkylthioalkyl, C₂ -C₄ cyanoalkyl, C₁ -C₃ alkoxy, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl; or

R₁₁ and R₁₂ may be taken together to form (CH₂)₃, (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ;

R₁₃ is H, C₁ -C₄ alkyl or C₁ -C₄ haloalkyl;

R₁₄ is C₁ -C₂ alkyl;

R₁₅ is H or CH₃ ;

R₁₆ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl;

R₁₇ is C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ alkylthio, C₁ -C₄ alkylamino or di(C₁ -C₄ alkyl)amino;

R₁₉ is H, C₁ -C₃ alkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl;

R₂₀ is H or C₁ -C₃ alkyl; or

R₁₉ and R₂₀ may be taken together to form (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ;

R₂₁ is C₁ -C₄ alkyl, C₁ -C₃ haloalkyl, C₂ -C₃ cyanoalkyl, cyclopropyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ alkoxyalkyl or C₁ -C₂ alkoxy;

R₂₂ is H or C₁ -C₄ alkyl;

R₂₃ is H or C₁ -C₄ alkyl;

R₂₄ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₁ -C₄ haloalkyl or phenyl which may be optionally substituted with R₂₅ ; or

R₂₃ and R₂₄ may be taken together to form (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ;

R₂₅ is H, CH₃, Cl, F, Br, NO₂, CF₃, CN or OCH₃ ;

m is 1 or 2;

n is 0, 1 or 2;

W₂ and W₃ are independently O or S;

A is ##STR17## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃ alkyl)amino;

Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₄ -C₅ cycloalkyl, C₂ -C₄ alkynyl, cyano, ##STR18## or N (OCH₃)CH₃ ; q is 2 or 3;

L₁ and L₂ are independently O or S;

R_(d) and R_(e) are independently C₁ -C₂ alkyl;

R_(f) is H or CH₃ ;

Z is CH or N;

Y₁ is O or CH₂ ;

X₁ is CH₃, OCH₃, OC₂ H₅ or OCF₂ H;

Y₂ is H or CH₃ ;

X₂ is CH₃, OCH₃ or SCH₃ ;

Y₃ is CH₃, CH₂ CH₃ or CH₂ CF₃ ;

X₃ is CH₃ or OCH₃ ;

X₄ is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃ or Cl; and

Y₄ is CH₃, OCH₃, OC₂ H₅ or Cl;

and their agriculturally suitable salts; provided that

(a) when X is Cl, F, Br or I, then Z is CH and Y is OCH₃, OC₂ H₅, N(OCH₃)CH₃, NHCH₃, N(CH₃)₂ or OCF₂ H;

(b) when X or Y is C₁ haloalkoxy, then Z is CH;

(c) when Q₁ is CF₃, then A is A-2, A-3, A-4, A-5, A-6 or A-7;

(d) when E is O or S and R₉ is H, then R₂ is other than CH₂ OR₉ ;

(e) when W is S, then A-1, R is H and Y is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃, CH(OCH₃)₂ or ##STR19## (f) the total number of carbon atoms in R₁ and Q is less than or equal to 10;

(g) when Q₁ is C₁ -C₄ haloalkyl or ##STR20## then X and Y are other than OCF₂ H or SCF₂ H; (h) X₄ and Y₄ cannot simultaneously be Cl;

(i) when R₁ is R₁ ' then L is L-1, L-3, L-5, L-6, L-8 or L-10;

(j) the total number of carbon atoms in R₂₂, R₂₃ and R₂₄ is less than or equal to 10;

(k) when R₂₁ is C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, C₁ -C₂ alkoxy or C₃ -C₄ alkenyl, then X and Y are other than OCF₂ H or SCF₂ H;

(l) when Y is CN and R₁ ' is H, F, Cl or CH₃, then R₂₁ is other than C₁ -C₃ alkyl;

(m) when R₁ is R₁ ' then Q is Q₁ ;

(n) when R₁ is R₁ " then Q is Q₁ or Q₂ ;

(o) when Q₂ is halogen then R_(x) is halogen;

(p) when R₁ " is SO₂ NR_(a) R_(b), CO₂ R_(c) or C(O)NR_(g) R_(h) when Q is SO₂ NHR₂₁, ##STR21## SO₂ NR₂₂ NR₂₃ R₂₄, SO₂ NH₂, SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n) or CHO then L is L-1, L-2, L-5 or L-6; and

(q) when Q₂ is halogen then L is L-2, L-4, L-5, L-6, L-7 or L-9.

Another aspect of this invention relates to a composition suitable for controlling the growth of undesired vegetation which comprises a herbicidally effective amount of a compound of formula I and a diluent, surfactant, or mixture thereof. Yet another aspect of the invention relates to a method for the control of undesired vegetation which comprises applying to the locus of the undesired vegetation a herbicidally effective amount of the compounds of formula I.

Preferred compounds for reasons of their higher herbicidal activity, greater plant growth regulant activity or more favorable ease of synthesis are:

(1) Compounds of Formula I wherein

R is R₁ ';

R₁ ' is H, CH₃, Cl, Br, OCH₃ or C₁ haloalkyl;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, F, Br, I, OCF₂ H, CH₂ F, CF₃, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl or CH₂ Br; and

Y is H, CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CH₂ CH₃, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OCH₂ CH₃, OCH₂ CH₂ OCH₃, CH₂ SCH₃, CH₂ SCH₂ CH₃, OCH₂ CH₂ OCH₃, ##STR22## OCF₂ H, SCF₂ H, C.tbd.CH or C.tbd.CCH₃.

(2) Compounds of Preferred 1 where A is A-1 and W is 0.

(3) Compounds of Preferred 2 where L is L-1 or L-3.

(4) Compounds of Preferred 2 where L is L-5, L-6, L-8or L-10.

(5) Compounds of Preferred 3 where

Q₁ is ER₂, ##STR23## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR24## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(6) Compounds of Preferred 5 where

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ;

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂ ;

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; and

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃.

(7) Compounds of Preferred 4 where

Q₁ is ER₂, ##STR25## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR26## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(8) Compounds of Preferred 7 where

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ;

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂ ;

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ HNC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; and

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃.

(9) Compounds of Formula I wherein

R₁ is R₁ ";

X is CH₃, OCH₃, OCH₂ CH₃, Cl, F Br, I, OCF₂ H, CH₂ F, CF₃, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl or CH₂ Br; and

Y is H, CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CH₂ CH₃, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OCH₂ CH₃, OCH₂ CH₂ OCH₃, CH₂ SCH₃, CH₂ SCH₂ CH₃, OCH₂ CH₂ OCH₃, ##STR27## OCF₂ H, SCF₂ H, C.tbd.CH or C.tbd.CCH₃.

(10) Compounds of Preferred 9 where W is 0.

(11) Compounds of Preferred 10 where L is L-1.

(12) Compounds of Preferred 10 where L is L-2.

(13) Compounds of Preferred 10 where L is L-3.

(14) Compounds of Preferred 10 where L is L-4.

(15) Compounds of Preferred 10 where L is L-5.

(16) Compounds of Preferred 10 where L is L-6.

(17) Compounds of Preferred 10 where L is L-7.

(18) Compounds of Preferred 10 where L is L-8.

(19) Compounds of Preferred 10 where L is L-9.

(20) Compounds of Preferred 10 where L is L-10.

(21) Compounds of Preferred 11 where

Q₁ is ER₂, ##STR28## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR29## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(22) Compounds of Preferred 21 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃, SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(23) Compounds of Preferred 22 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

(24) Compounds of Preferred 12 where

Q₁ is ER₂, ##STR30## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR31## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(25) Compounds of Preferred 24 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(26) Compounds of Preferred 25 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

(27) Compounds of Preferred 13 where

Q₁ is ER₂, ##STR32## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR33## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(28) Compounds of Preferred 27 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(29) Compounds of Preferred 28 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

(30) Compounds of Preferred 14 where

Q₁ is ER₂, ##STR34## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR35## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃, or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(31) Compounds of Preferred 30 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(32) Compounds of Preferred 31 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

(33) Compounds of Preferred 15 where

Q₁ is ER₂, ##STR36## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR37## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(34) Compounds of Preferred 33 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(35) Compounds of Preferred 34 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

(36) Compounds of Preferred 16 where

Q₁ is ER₂, ##STR38## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR39## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(37) Compounds of Preferred 36 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(38) Compounds of Preferred 37 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₅ OCH₃, NHCH₃ or CH(OCH₃)₂.

(39) Compounds of Preferred 17 where

Q₁ is ER₂, ##STR40## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR41## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(40) Compounds of Preferred 39 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(41) Compounds of Preferred 40 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

(42) Compounds of Preferred 18 where

Q₁ is ER₂, ##STR42## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR43## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(43) Compounds of Preferred 42 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(44) Compounds of Preferred 43 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

(45) Compounds of Preferred 19 where

Q is ER₂, ##STR44## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR45## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(46) Compounds of Preferred 45 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(47) Compounds of Preferred 46 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

(48) Compounds of Preferred 20 where

Q₁ is ER₂, ##STR46## C₁ -C₂ alkyl substituted with R₈, C₁ -C₂ haloalkyl, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR47## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;

R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ;

R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and

R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.

(49) Compounds of Preferred 48 where

Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl, CN or SO₂ NHC₁ -C₂ alkyl;

E is S or SO₂ ;

R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl;

R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ;

Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl;

R_(a) is H or C₁ -C₂ alkyl;

R_(b) is C₁ -C₂ alkyl;

R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ;

R_(g) is H or C₁ -C₂ alkyl;

R_(h) is CH₃ ;

R_(i) is C₁ -C₂ alkyl; and

R_(j) is C₁ -C₂ alkyl.

(50) Compounds of Preferred 49 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

Specifically preferred for reasons of greatest ease of synthesis and/or greatest herbicidal efficacy are:

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide, m.p. 171°-173° C.;

N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesufonamide, m.p. 155°-156° C.;

N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-4-cyano-3-thiophenesulfonamide, m.p. 189°-192° C.;

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(2-methoxyethyl)-2-thiophenesulfonamide, m.p. 173°-176° C.;

3-[[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-4-(propylsulfinyl)-2-thiophenecarboxylic acid, methyl ester, m.p. 178°-179° C.; and

3-[[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-4-(propylsulfinyl)-2-thiophenecarboxylic acid, methyl ester, m.p. 112°-113° C.

In the above definitions, the term "alkyl", used either alone or in compound words such as "alkylthio" or "haloalkyl", denotes straight chain or branched alkyl, e.g. methyl, ethyl, n-propyl, isopropyl or the different butyl, pentyl or hexyl isomers.

Alkoxy denotes methoxy, ethoxy, n-propyloxy, isopropyloxy and the different butyl isomers.

Alkenyl denotes straight chain or branched alkenes, e.g. vinyl, 1-propenyl, 2-propenyl, 3-propenyl, isopropenyl and the different butenyl, pentenyl or hexenyl isomers.

Alkynyl denotes straight chain or branched alkynes, e.g. ethynyl, 1-propynyl, 2-propynyl and the different butynyl, pentynyl or hexynyl isomers.

Alkylcarbonyl denotes, e.g., acetyl, propionyl and the different butyryl isomers.

Alkylsulfonyl denotes methylsulfonyl, ethylsulfonyl or the different propylsulfonyl and butylsulfonyl isomers.

Cycloalkyl denotes cyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl.

The term "halogen", either alone or in compound words such as "haloalkyl", denotes fluorine, chlorine, bromine or iodine. Further, when used in compound words such as "haloalkyl" said alkyl may be partially halogenated or fully substituted with halogen atoms which may be the same or different. Examples of haloalkyl include CH₂ CH₂ F, CF₂ CF₃ and CH₂ CHFCl.

The total number of carbon atoms in a substituent group is indicated by the C_(i) -C_(j) prefix where i and j are numbers from 1 to 6. For example, C₁ -C₃ alkylsulfonyl would designate methylsulfonyl through propylsulfonyl, C₂ alkoxyalkoxy would designate OCH₂ OCH₃, C₂ cyanoalkyl would designate CH₂ CN and C₃ cyanoalkyl would designate CH₂ CH₂ CN and CH(CH)CH₃.

DETAILED DESCRIPTION OF THE INVENTION Synthesis

The compounds of Formula I can be prepared by one or more of the methods described below in Equations 1 through 4.

Many of the compounds of Formula I can be prepared by reaction of a sulfonamide of Formula 2 with an appropriate methyl carbamate of Formula 3 in the presence of at least an equimolar amount of trimethylaluminum, according to Equation 1. ##STR48## This reaction is carried out at 25° to 40° C. under an inert atmosphere and in an inert, dipolar aprotic solvent such as methylene chloride for 10 to 96 hours. Details of this reaction as well as the preparation of the carbamates of Formula 3 can be found in EPO Publication No. 13,480.

Many of the compounds of Formula I also can be prepared by reacting a sulfonylcarbamate of Formula 4 with an appropriate heterocyclic amine of Formula 5, according to Equation 1a. ##STR49## The reaction is carried out at 50° to 100° C. in a solvent such as 1,4-dioxane for 0.5 to 24 hours according to EPO Publication No. 44807. The required carbamates of Formula 4 are prepared by reacting the appropriate sulfonamide, 2, with diphenylcarbonate in the presence of equimolar quantities of a strong base, such as sodium or potassium hydride.

Some of the compounds of Formula I also can be prepared as shown in Equation 2. ##STR50## wherein Y' is CH₃, C₂ H₅ or CH₂ CF₃.

This reaction series is performed according to the procedures disclosed by EPO Publication No. 30,140 and the requisite heterocyclic isocyanates of Formula 6 can be prepared according to methods described in Swiss 579,062, U.S. Pat. No. 3,919,228, U.S. Pat. No. 3,732,223 and U. von Gizycki, Agnew. Chem. Int. Ed. Engl. 1976, 10, 402 and 403.

Compounds of Formula I also may be prepared by reaction of a thienylsulfonylisocyanate of Formula 8 with the appropriate heterocyclic amine, as shown in Equation 3. ##STR51## wherein Q, R₁ and A are as previously defined provided R_(a), R_(b), R₄, R₉, R₁₁, R₁₂, R₁₉ and R₂₀ are not H; J is not NH and R₅, R₆ and R₇ are not alkylamino.

The reaction of Equation 3 is most successful when performed in an inert dipolar aprotic solvent such as methylene chloride, tetrahydrofuran or acetonitrile at temperatures between 20° and 80° C. A catalytic amount of 1,4-diazabicyclo[2.2.2]octane (Dabco®) may be used to accelerate the reaction. In cases where the products are insoluble in the reaction solvent, isolation may be performed by simple filtration; when the products are soluble, isolation may be performed by evaporation of the solvent, trituration with a solvent such as 1-chlorobutane, diethyl ether or methanol and filtration.

Thienylsulfonylisocyanates of Formula 8 can be prepared from sulfonamides of Formula 2 by methods described in U.S. Pat. No. 4,238,621, as indicated in Equation 3a. Alternatively, these sulfonylisocyanates can be synthesized via a two-step procedure, consisting of (1) reacting sulfonamide 2 with n-butylisocyanate in the presence of one molar equivalent of a base such as potassium carbonate in a solvent such as 2-butanone or acetonitrile to form n-butylsulfonylureas of Formula 9, and (2) reaction of 9 with phosgene using Dabco® as a catalyst in refluxing xylene as solvent. This method is similar to the preparation found in "Newer Methods of Preparative Organic Chemistry," Forest, W., Ed., Vol. VI, Academic Press, NY, 1967, pp. 223-241. Equation 3b illustrates the procedure, ##STR52## wherein the substituents are as defined for Equation 3 above.

The compounds of Formula I also are available by the methodology described in South African Application No. 830441 and illustrated by Equation 4. Thienylsulfonamides of Formula 2 react with heterocyclic carbamates of Formula 10 in 1,4-dioxane at 20° to 80° C. for periods of 1 to 24 hours when 1 equivalent of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) is added to the reaction mixture. The resultant products are isolated by dilution of the reaction mixture with water, acidification and subsequent filtration. Heterocyclic carbamates of Formula 10 in turn are synthesized by reaction of heterocyclic amines of Formula 5 with diphenyl carbonate or phenyl chloroformate in pyridine at temperatures ranging from 20° to 80° C., as indicated in Equation 4a. ##STR53##

The synthesis of thienylsulfonylureas of Formula I relies upon the requisite intermediate thiophenesulfonamides of Formula 2.

Some of the intermediate sulfonamides of Formula 2 described above can be prepared from amines of Formula 11 by a two-step procedure, as shown in Equation 5. This consists of (5a) diazotizing 11 and coupling the diazonium salt with sulfur dioxide to form a sulfonyl chloride of Formula 12; and (5b) aminating 12 with ammonium hydroxide or anhydrous ammonia to form 2. ##STR54##

The reaction of Equation 5a is accomplished by treating a solution of amine 11 in a mixture of concentrated hydrochloric acid and glacial acetic acid with a solution of sodium nitrite in water at -5° to 5° C. After being stirred for 10-30 minutes at about 0° C. to insure complete diazotization, the solution is added to a mixture of an excess of sulfur dioxide and a catalytic amount of copper(I) chloride or copper(II) chloride in glacial acetic acid at about 10° C. The temperature is kept at about 10° C. for 1/4 to 1 hour, then raised to 20° to 30° C. and held at that temperature for 2 to about 24 hours. This solution is then poured into a large excess of ice water. The sulfonyl chloride 12 can be isolated by filtration or by extraction into a solvent such as ethyl ether, methylene chloride or, preferably, 1-chlorobutane followed by evaporation of the solvent.

The amination described in the reaction of Equation 5b above is conveniently carried out by treating a solution of the sulfonyl chloride 12 with at least two mole equivalents of anhydrous ammonia in a solvent such as ethyl ether or methylene chloride at -20° to 30° C. If the sulfonamide product 2 is insoluble, it may be isolated by filtration followed by washing out the salts with water. If product 2 is soluble in the reaction solvent, it may be isolated by filtering off the precipitated ammonium chloride and evaporation of the solvent. Alternatively, many sulfonamides 2 can be prepared by reaction of corresponding sulfonyl chlorides 12 with excess aqueous ammonium hydroxide in tetrahydrofuran at 0° to about 40° C. for 0.5 to 10 hours. The sulfonamide product 2 is isolated by evaporation of the tetrahydrofuran solvent, addition of water to the residue and filtration.

Alternatively, the intermediate sulfonyl chloride 12 can be prepared as shown below in Equation 6. ##STR55##

According to Equation 6, a lithium salt, prepared by reaction of 13 with n-butyllithium in ether at about -70° C., is added to sulfuryl chloride in hexane at about -30° to -20° C. and stirred for 0.5 to 10 hours at -30° to 30° C. to yield sulfonyl chloride 12, according to teachings of S. N. Bhattacharya, C. Earborn and D. R. M. Walsh, J. Chem. Soc. (C) 1968, 1265 and H. Quast and F. Kee, Synthesis 1974, 489. Subsequent reaction of 12 with ammonia or ammonium hydroxide as described above provides the corresponding sulfonamide.

Starting with an appropriate bromothiophene, and carrying out the procedures described in Equation 6, or simple modifications thereof, one skilled in the art may prepare some of the other sulfonyl chlorides of Formula 12 described above. Of necessity, the reactions are limited to those cases in which the substituents Q and R₁ are inert to lithium reagents under the conditions of the reactions, which will be obvious to one skilled in the art. For reviews of metallation with lithium reagents, see H. W. Gschwend and H. R. Rodriguez, Org. Reactions 1979, 26, 1; and N. S. Narasimhan, R. S. Mali, Synthesis 1983, 957.

Some sulfonamides 2 are best prepared by the procedure of Equation 7 below. ##STR56##

The preparation of sulfinic acid salts 14 by the procedure of Equation 7 is well known in the art; see U.S. Pat. No. 4,441,910 and H. W. Gschwend et al., loc. cit. Sulfonamides 2 can be prepared by treatment of sulfinic acid salts with chloramine. In this procedure an ethereal solution of suspension of the salt 14 is treated at low temperature (25° to -30° C.) with a dry ethereal solution of chloramine. The reaction is stirred for a period of several minutes to several hours. After filtration, the reaction mixture is washed with aqueous bisulfite, dried and the solvent removed on a rotary evaporator. The crude product is further purified by usual methods such as crystallization or chromatography.

In the reaction shown in Equation 8, a thienyl copper compound of Formula 15 is reacted with an iodo or bromo compound QX, where X is I or Br, in a solvent such as pyridine or quinoline. The copper compounds of Formula 15 are prepared by reacting the corresponding lithium compounds with cuprous iodide or cuprous bromide in a solvent such as diethyl ether. Detailed procedures for these reactions are described in the following references: M. Nilsson and C. Ullenius, Acta Chem. Scand. 1970, 24, 2379-2388; C. Ullenius, Acta Chem. Scand. 1972, 26, 3383-3386. ##STR57##

Alternatively, compounds of Formula 16 wherein Q is CN can also be prepared as shown in Equation 8a by the reaction of a bromothiophenesulfonamide of Formula 15a with cuprous cyanide in a solvent such as dimethylformamide at ambient to reflux temperature. Detailed procedures for this reaction are described below. ##STR58## Treatment of the compounds of Formula 16 with an acid catalyst in an alcohol solvent or in trifluoroacetic acid removes the t-butyl group to yield compounds of Formula 2 as shown in Equation 9. ##STR59##

Starting with the appropriate 3-substituted thiophene and following the metallation procedure indicated in Equation 7 or simple modifications thereof, one skilled in the art may prepare many of the sulfonamides of Formula 2. Only those 3-substituents which are inert to metallating reagents relative to the desired 2-metallation of the thiophene nucleus are compatible with this synthetic strategy; such substituents will be obvious to one skilled in the art.

In complement to the metallation-chlorosulfonation sequence illustrated by Equation 6, equivalent metallation-sulfination may be performed to obtain the sulfonamides of Formula 2a. The latter sequence is described by Equation 10 and is entirely analogous to that of Equation 7. ##STR60##

Once sulfinate salts of Formula 18 have been made, they may be transformed into sulfonamides 2a directly by reaction with chloramine as described by G. H. Coleman and C. R. Hauser J. Am. Chem. Soc. 1928, 50, 1193. Sulfinate salts of Formula 18 also may be converted to 2a in a two-step process: chlorination to afford a sulfonyl chloride, as practiced by J. F. Sculley and E. V. Brown J. Org. Chem. 1954, 19, 894; W. E. Trull and E. Wellisch J. Am. Chem. Soc. 1952, 74, 5177 and Y. K. Yuriev and N. K. Sadavaya J. Gen. Chem. USSR 1964, 34, 1814 and treatment of that sulfonyl chloride with ammonia in an ethereal solvent such as THF. Any of these procedures also are compatible with those sulfinate salts of Formula 14 generated via Equation 7.

The use of the strategy of Equation 11 is especially appealing in those cases where metallation of the 3-substituted thiophene of Formula 17 in the 2-position is not possible due to the reactivity of O under the conditions of metallation. Formation of the 2-brominated thiophene 19 allows for exceedingly facile, mild halogen-metal exchange conditions as shown in Equation 11. ##STR61##

Electrophilic aromatic bromination of 3-substituted thiophenes of Formula 17 leads to the 2-brominated compounds of Formula 19 selectively, as shown in the teachings of S. Gronowitz, P. Moses and A. B. Hornfeldt Ark. Kem. 1962, 17, 165. Subsequent halogen-metal exchange and sulfination with sulfur dioxide gives the sulfinate salts 18, or sulfonation with sulfuryl chloride leads to the sulfonyl chlorides 20.

In still other cases where Q will suffer addition of most nucleophiles, Q can be placed at the 3-position of the thiophene nucleus after the sulfonamide moiety or its synthetic equivalent has been incorporated at the 2-position. This strategy is shown in Equation 12. ##STR62##

2,3-Dibromothiophene 21 can be lithiated preferentially at the 2-position and treated with sulfuryl chloride to give the sulfonyl halide 22. Treatment with tert-butylamine results in the tert-butyl-protected sulfonamide of Formula 23. A second lithium-halogen exchange reaction allows for 3-substitution of the heterocycle, Q, which may be added as an intact entity or as a synthetically equivalent substructure.

Sulfonamides of Formula 2a can also be prepared by the sequence shown in Equation 13. ##STR63##

Sulfonamides of Formula 2b can be prepared by use of the strategy shown in Equation 14. ##STR64##

3,4-Dibromothiophene, 29 can be metallated at the 3-position and treated with disulfide to give thio compound 30. A second lithium exchange followed by reaction with sulfur dioxide and N-chlorosuccinimide treatment of the lithium sulfinate salt results in the sulfonyl halide 31. Treatment with tert-butylamine gives the tert-butyl-protected sulfonamide of Formula 32. Reaction with 2 equivalents of butyllithium followed by carbon dioxide treatment yields the 2-substituted acid 33. Esterification, followed by trifluoroacetic acid treatment gives 2b.

Reaction of the dianion from 32 with electrophiles allows for 2-substitution of the thiophene as shown in Equation 15. ##STR65##

Thio compounds such as 34 or 35 can be oxidized by standard methods known to anyone skilled in the art to prepare sulfinyl and sulfonyl compounds such as 36 and 37 as shown in Equations 16a and 16b. ##STR66##

Sulfonamides of Formula 2b can also be prepared by the strategy shown in Equation 17. ##STR67##

The tert-butyl-protected sulfonamide 32 can be treated with chlorine in acid to give sulfonyl chloride 38. Standard reaction with amines then yields disulfonamide 39 which can be lithiated and reacted with electrophiles to give 2-substituted-disulfonamide 40. The tert-butyl sulfonamide can then be deprotected with trifluoroacetic acid to afford 2b.

Sulfonamides of Formula 2c can be prepared by the strategy shown in Equation 18. ##STR68##

The thio-bromide 30 can be lithiated preferentially at the 3-position and reacted with carbon dioxide to give acid 41. The dianion of this acid can easily be formed and allows for 2-substitution of the heterocycle with Q which may be added as an intact entity or as a synthetically equivalent substructure. Esterification of the acid 42 by standard methods gives 43 which is treated with chlorine in acid to yield sulfonyl chloride 44. Amination then affords sulfonamide of structure 2c.

A judicious choice of the appropriate methods for preparing compounds of Formula 2 must take into account the nature of the substituents Q and R₁, and their chemical compatibility with the reaction conditions of Equations 1-18.

The heterocyclic amines of Formula 5 in Equation 1a above can be prepared by methods known in the literature, or simple modifications thereof, by those skilled in the art. For instance, EP-A No. 84,224 (published in July 27, 1983) and W. Braker et al., J. Am. Chem. Soc., 69, 3072 (1947) describe methods for preparing aminopyrimidines and triazines substituted by acetal groups such as dialkoxymethyls or 1,3-dioxolan-yl, among other groups. Also, for example, South African patent application Nos. 82/5045 and 82/5671 describe methods for preparing aminopyrimidines and triazines substituted by haloalkyl or haloalkylthio groups such as OCH₂ CH₂ F, OCH₂ CF₃, SCF₂ H, or OCF₂ H, among other groups. South African patent application No. 83/7434 (published Oct. 5, 1983) describes methods for the synthesis of cyclopropylpyrimidines and triazines substituted by such groups as alkyl, haloalkyl, alkoxy, haloalkoxy, alkylamino, dialkylamino or alkoxyalkyl.

The 5,6-dihydrofuro[2,3-d]pyrimidine-2-amines, the cyclopenta[d]pyrimidines-2-amines (5, A is A-2) and the 6,7-dihydro-5H-pyrano[2,3-d]pyrimidin-2-amines (5, A is A-3) can be prepared as described in EP-A No. 15,683. The furo[2,3-d]pyrimidin-2-amines (5, A is A-4) are described in EP-A No. 46,677.

Compounds of Formula 5 where is A-5, are described in EP-A-73,562. Compounds of Formula 5 where A is A-6, are described in EP-A-94,260.

In addition, general methods for preparing aminopyrimidines and triazines have been reviewed in the following publications:

"The Chemistry of Heterocyclic Compounds", a series published by Interscience Publishers, Inc., New York and London;

"Pyrimidines", Vol. 16 of the same series by D. J. Brown;

"s-Triazines and Derivatives", Vol. 13 of the same series by E. M. Smolin and L. Rappoport; and

F. C. Schaefer, U.S. Pat. No. 3,154,547 and K. R. Huffman and F. C. Schaefer, J. Org. Chem., 28, 1812 (1963), which describes the synthesis of triazines.

Agriculturally suitable salts of compounds of Formula I are also useful herbicides and can be prepared in a number of ways known to the art. For example, metal salts can be made by contacting compounds of Formula I with a solution of an alkali or alkaline earth metal salt having a sufficiently basic anion (e.g., hydroxide, alkoxide or carbonate). Quaternary amine salts can be made by similar techniques.

Salts of compounds of Formula I can also be prepared by exchange of one cation for another. Cationic exchange can be effected by direct contact of an aqueous solution of a salt of a compound of Formula I (e.g., alkali or quaternary amine salt) with a solution containing the cation to be exchanged. This method is most effective when the desired salt containing the exchanged cation is insoluble in water and can be separated by filtration.

Exchange may also be effected by passing an aqueous solution of a salt of a compound of Formula I (e.g., an alkali metal or quaternary amine salt) through a column packed with a cation exchange resin containing the cation to be exchanged for that of the original salt and the desired product is eluted from the column. This method is particularly useful when the desired salt is water-soluble, e.g., a potassium sodium or calcium salt.

Acid addition salts, useful in this invention, can be obtained by reacting a compound of Formula I with a suitable acid, e.g., p-toluenesulfonic acid, trichloroacetic acid or the like.

The preparation of the compounds of this invention is further illustrated by the following specific examples.

EXAMPLE 1 3-(Methoxymethyl)thiophene-2-sulfonamide

To 22.3 g of 3-(methoxymethyl)thiophene dissolved in 180 mL of dry ether under nitrogen is added, dropwise with stirring at 0° C., 120 mL of a 1.6M solution of n-butyllithium in hexane. The mixture is stirred at 0° C. for two hours, and 24.1 g of sulfuryl chloride is added while the temperature is maintained at -40° C. After two hours 5 mL of ethyl acetate is added and the reaction mixture is poured into ice and water. The organic phase is separated and added to 25 mL of concentrated ammonium hydroxide at ambient temperature.

After evaporation of the ether and hexane from the reaction mixture, the desired sulfonamide can be separated from the aqueous residue, washed with water and dried. The product can be purified by chromatography using procedures described by W. C. Still et al., J. Org. Chem., 43, 2923 (1978).

EXAMPLE 2 N-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(methoxymethyl)thiophene-2-sulfonamide

To 0.41 g of 3-(methoxymethyl)thiophene-2-sulfonamide and 0.55 g of phenyl N-(4,6-dimethoxypyrimidin-2-yl)carbamate in 20 mL of acetonitrile is added 0.3 mL of 1,8-diazabicyclo-[5.4.0]undec-7-ene (DBU). After being stirred for 2 hours at ambient temperature and pressure, the reaction mass is poured onto 25-50 g of ice and the resultant mixture acidified to pH 3 by the addition of hydrochloric acid. The desired solid product can be isolated by filtration. Alternatively, it can be extracted into methylene chloride which is then dried over magnesium sulfate, filtered and evaporated to dryness to yield the desired product is sufficiently pure form for the purposes of this invention.

EXAMPLE 3 N-[(4-Methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-3-(methoxymethyl)thiophene-2-sulfonamide

To 0.41 g of 3-(methoxymethyl)thiophene-2-sulfonamide and 0.52 g of phenyl N-(4-methoxy-6-methylpyrimidin-2-yl)carbamate in 25 mL of 1,4-dioxane is added 0.3 mL of 1,8-diazabicyclo[5.4]undec-7-ene. After being stirred for two hours at ambient temperature and pressure, the reaction mixture is poured onto 25-50 g of ice and the resultant mixture is acidified to pH 3 by the addition of hydrochloric acid. The desired solid product can be isolated by filtration. Alternatively, it can be extracted into methylene chloride which is then dried over magnesium sulfate, filtered and evaporated to dryness to yield the desired product in sufficiently pure form for the purposes of this invention.

EXAMPLE 4 3-(2-Methoxyethyl)thiophene-2-sulfonyl chloride

To 56 g of chlorosulfonic acid at -15° C. was added with efficient stirring 14.2 g of 3-(2-methoxyethyl)thiophene. The mixture was stirred for one hour at -10° C. and then cautiously added to ice and the resultant mixture extracted with methylene chloride. The methylene chloride extract was washed with cold water, dried over magnesium sulfate, filtered and concentrated to yield 6.0 g of an oil. Infrared absorption spectroscopy showed peaks at 1160, 1180 and 1360 cm⁻¹ consistent for sulfonyl chloride. This product was sufficiently pure for use as an intermediate for the preparation of compounds of this invention.

EXAMPLE 5 3-(2-Methoxyethyl)thiophene-2-sulfonamide

Six grams of crude 3-(2-methoxyethyl)thiophene-2-sulfonyl chloride was dissolved in 25 mL of acetone and added dropwise with stirring at ambient temperature to 25 mL of concentrated aqueous ammonium hydroxide. The reaction mixture was allowed to stand overnight and the acetone removed by evaporation. The aqueous residue was extracted with three 100 mL portions of methylene chloride which were combined, dried over magnesium sulfate, filtered and evaporated to yield a residue which was a mixture of an oil and a solid. The sulfonamide was isolated by passing the residue through a 30 cm high by 80 mm diameter column of silica gel using 1:1 ethyl acetate mixed hexanes solvent system and taking 100 mL fractions. The desired product came off in fractions 4 to 12. After evaporation of the solvent 1.84 grams was obtained, m.p. 64°-73°. Analysis by mass spectroscopy showed a molecular weight of 221 AMU in agreement for the desired sulfonamide.

EXAMPLE 6 N-[(4-Chloro-6-methoxypyrimidin-2-yl)aminocarbonyl]-3-(2-methoxyethyl)thiophene-2-sulfonamide

To a solution of 0.33 g of 3-(2-methoxyethyl)thiophene-2-sulfonamide and 0.42 g of phenyl N-(4-chloro-6-methoxypyrimidin-2-yl)carbamate in 20 mL of acetonitrile was added with stirring at ambient temperature 0.23 mL of DBU. After stirring for two hours the mixture was poured into 25 g of ice and water, acidified with 12N hydrochloric acid and the resultant precipitate removed by filtration, washed with cold water and dried to yield 0.37 g of product, m.p. 135°-141° C. It showed peaks by infrared absorption spectroscopy at 1700, 1600 and 1560 cm⁻¹ consistent for the desired structure.

NMR (CDCl₃) 3.27 δ, s, CH₃ O; 3.27 δ, t, CH₂ ; 3.65 δ, t, CH₂ ; 4.02 δ, t, CH₃ O on pyrimidine; 6.49 δ, s, CH of pyrimidine; 7.05 δ, d, 7.60 δ, d, thiophene; 7.05 δ, ws, NH between ##STR69## and hetero; and 12.0 δ, s, NH (imide).

EXAMPLE 7 N-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(2-methoxyethyl)-2-thiophenesulfonamide

To a mixture of 0.33 g of 3-(2-methoxyethyl)thiophene-2-sulfonamide and 0.41 g of phenyl N-(4,6-dimethoxypyrimidin-2-yl)carbamate in 20 mL of acetonitrile was added 0.23 mL of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) at ambient temperature with stirring. After 2 hours the mixture was poured onto ice and acidified with 12N hydrochloric acid. The resultant precipitate was removed by filtration, washed with water and dried to yield 0.42 g, m.p. 173°-176°.

NMR (CDCl₃): 3.268 δ, s, CH₃ O; 3.27 δ, t, CH₂ ; 3.64 δ, t, CH₂ ; 3.98 δ, s, 2 X CH₃ O of pyrimidine; 5.78 δ, s, CH of pyrimidine; and 7.2, 7.6 δ, d, 2 X CH of thiophene.

EXAMPLE 8 2-Hydroxymethylthiophene-3-sulfonamide

To 5.0 g of methyl 3-aminosulfonylthiophene-2-carboxylate in 200 mL of tetrahydrofuran was added 0.75 g of lithium borohydride. After heating at reflux for two hours the reaction was quenched with water and acidified with concentrated hydrochloric acid. The desired product was then extracted into methylene chloride which was washed with water, dried over magnesium sulfate, filtered and concentrated in vacuo to yield 1.8 g of a yellow solid, m.p. 85°-89°.

NMR (CDCl₃): 7.3 δ, AB quartet, 2H on thiophene; 6.8 δ, sw, 2H of NH₂ ; 5.4 δ, s, 1H of OH; and 4.95 δ, d, 2H of CH₂.

EXAMPLE 9 2-Chloromethylthiophene-3-sulfonamide

To a stirred suspension of 16 g of 2-hydroxymethylthiophene-3-sulfonamide, 150 mL of methylene chloride and 10.5 mL of N,N-dimethylaniline was added 6.0 mL of thionyl chloride. An ice cooling bath was applied when the reaction temperature rose to 40° and the mixture was cooled to room temperature. It was then diluted with 50 mL of 1-chlorobutane followed by the addition of 200 mL of ice and water. The precipitate thus formed was isolated by filtration, washed with water and air-dried to yield 12.2 g of white solid, m.p. 100° dec.

NMR (CDCl₃ -DMSO): 7.4 δ, s, 2H, thiophene; 7.4-5.5 δ, vbs, 2H, NH₂ ; and 5.2 δ, s, 2H, CH₂.

EXAMPLE 10 3-Cyano-N-(1,1-dimethylethyl)thiophene-2-sulfonamide

A mixture of 197.7 g of 3-bromo-N-(1,1-dimethylethyl)thiophene-2-sulfonamide, 195.9 g of cuprous cyanide and 500 mL of dimethylformamide was heated to 150° for two one half hours at which time none of the bromothiophene remained as indicated by thin layer chromatography. The reaction was cooled to room temperature and poured into 1500 mL of 10% aqueous sodium cyanide. The aqueous mixture was extracted with five, 200 mL portions of ethyl ether and the combined extracts were washed with five, 150 mL portions of water followed by one, 200 mL aqueous sodium chloride wash. After drying over magnesium sulfate, filtration and evaporation of the solvent 140.8 g of the desired product was obtained.

EXAMPLE 11 3-Cyanothiophene-2-sulfonamide

Ten grams of 3-cyano-N-(1,1-dimethylethyl)thiophene-2-sulfonamide was dissolved in 500 mL of trifluoroacetic acid and stirred overnight at room temperature. After removal of the solvent by evaporation, the residue was dissolved in ethyl acetate and washed with four portions of 100 mL of water followed by saturated sodium chloride. After drying over magnesium sulfate, the solvent was evaporated in vacuo to yield 6.42 g of white solid, m.p. 152°-155°. It showed peaks by Nuclear Magnetic Resonance consistent for the desired structure.

EXAMPLE 12 4-Propylthio-3-bromothiophene

A solution of 199 mL of 2.18M n-butyllithium in 320 mL ether was cooled to -80° C. and was treated dropwise with a solution of 100 g 3,4-dibromothiophene in 320 mL ether keeping the temperature below -70° C. After stirring another 30 minutes at -80° C. a solution of 94 mL dipropyl disulfide in 120 mL ether was added dropwise. The suspension was stirred at -80° C. for 2 hours, warmed to 20° C., poured into ice and hydrochloric acid and the organic phase was separated. The aqueous phase was extracted 2 times with ethyl acetate and the combined organic phases were washed with brine, dried (MgSO₄) and concentrated to an amber oil. The product (90.2 g) was isolated by distillation of the residue; bp 93°-96° C. at 0.5 torr.

EXAMPLE 13 4-Propylthio-N-(1,1-dimethylethyl)-3-thiophenesulfonamide

A solution of 44.7 g 4-propylthio-3-bromothiophene in 250 mL ether was added dropwise to a solution of 85 mL 2.0M n-butyllithium in ether (250 mL) cooled to -80° C. After stirring at -80° C. for an additional 30 minutes, a solution of 21.5 mL sulfur dioxide in 50 mL ether was slowly added keeping the temperature below -60° C. The suspension was warmed to 20° C. and concentrated to a white solid. The solid was dissolved in 300 mL acetic acid and cooled to about 16° while 21.9 g N-chlorosuccinimide was added in portions. After stirring at 20° C. overnight the acetic acid was removed in vacuo and the residue was triturated with 1 l ether, filtered and the ether was washed with saturated aqueous bicarbonate and brine, dried (MgSO₄), and concentrated to a dark oil. The oil was dissolved in 600 mL ether, cooled to - 10° C. and 50.4 mL t-butyl amine was added. The mixture was warmed to 20°, diluted with ethyl acetate and washed with water and brine, dried (MgSO₄) and concentrated to an oil. The product was isolated as a tan solid after chromatography on silica with 10% ethyl acetate in hexane; yield 20.8 g; m.p. 61°-63° C.

EXAMPLE 14 4-Propylthio-3-(N-(1,1-dimethylethyl)aminosulfonyl)-2-thiophenecarboxylic acid

A solution of 12.15 g 4-propylthio-3-N-(1,1-dimethylethyl)-3-thiophenesulfonamide in 150 mL THF was cooled to -30° C. and treated dropwise with 31.6 mL 2.69M n-butyllithium in hexane. The solution was warmed to 20° C. for 1.5 hours and then cooled to -80° C. 8.8 g Solid carbon dioxide was added in one portion, the mixture was warmed to 20° C. and poured over ice and hydrochloric acid. The organic layer was separated and the aqueous layer was extracted with ethyl acetate. The combined organic layers were washed with brine, dried and concentrated to a solid. The product was purified by recrystallization from butyl chloride to give 10.4 g of light yellow solid; m.p. 123°-126° C.

EXAMPLE 15 4-Propylthio-3-(N-(1,1-dimethylethyl)aminosulfonyl)-2-thiophenecarboxylic acid, methyl ester

Thionyl chloride (2.3 mL) was added dropwise to 110 mL methanol cooled to -10° C. Next 10.4 g 4-propylthio-3-(N-(1,1-dimethylethyl)aminosulfonyl)-2-thiophenecarboxylic acid was added in one portion. The solution was warmed to reflux for 6 hours, then cooled to -45° C., and the product precipitated in sufficiently pure form for the purposes of this invention; yield 8.45 g; m.p. 93°-98° C.

EXAMPLE 16 4-Propylsulfinyl-3-(N-(1,1-dimethylethyl)aminosulfonyl)-2-thiophenecarboxylic acid, methyl ester

A solution of 2.32 g 4-propylthio-3-(N-(1,1-dimethylethyl)aminosulfonyl)-2-thiophenecarboxylic acid, methyl ester in 75 mL methylene chloride was cooled to -80° C. and 1.39 g of 80-85% m-chloroperoxybenzoic acid was added in one portion. After stirring at -80° C. for 20 minutes and warming to 20° C. the solution was diluted with more methylene chloride and washed with aqueous sodium bicarbonate, sodium bisulfite, sodium bicarbonate and water, dried and concentrated to 2.2 g of colorless oil in sufficiently pure form for the purposes of this invention.

EXAMPLE 17 4-Propylsulfinyl-3-aminosulfonyl-2-thiophenecarboxylic acid, methyl ester

A solution of 2.2 g of 4-propylsulfinyl-3-(N-(1,1-dimethylethyl)aminosulfonyl)-2-thiophenecarboxylic acid, methyl ester in 15 mL methylene chloride was treated with 30 mL trifluoroacetic acid at room temperature for 24 hours. The solvent were removed in vacuo and the residue was crystallized with butyl chloride to give 1.74 g white solid; m.p. 131°-144° C.

EXAMPLE 18 3-[[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-4-propylsulfinyl-2-thiophenecarboxylic acid, methyl ester

To 0.28 g of 4-propylsulfinyl-3-aminosulfinyl-2-thiophenecarboxylic acid, methyl ester in 5 mL acetonitrile was added 0.32 g (4,6-dimethoxypyrimidin-2-yl)phenylcarbamate and 172 μL 1,8-diazabicyclo[5.4.0]undec-7-ene. After stirring at 20° C. for 30 minutes, 25 mL water was added and the product precipitated by addition of 1N hydrochloric acid, and purified by washing with water, butyl chloride and ether; yield 0.24 g; m.p. 178°-179° C.

NMR (CDCl₃) 12.95 δ, br s, 1H, thiophene; 7.20 δ, br s, 1H, NH; 5.82 δ, s, 1H, pyrimidine; 4.03 δ, s, 6H, pyrimidine OCH₃ ; 3.87 δ, s, 3H, COOCH₃ ; 3.5-3.7 δ, m, 1H, S(O)CH_(a) H_(b) --; 2.9-3.1 δ, m, 1H, S(O)CH_(a) H_(b) --; 1.7-2.1 δ, m, 2H, --CH₂ --; and 1.09 δ, t, J=7 Hz, 3H, --CH₃.

EXAMPLE 19 3-[[(4-Methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-4-(propylsulfinyl)-2-thiophenecarboxylic acid, methyl ester

To 0.28 g of 4-propylsulfinyl-3-aminosulfinyl-2-thiophenecarboxylic acid, methyl ester in 5 mL acetonitrile was added 0.30 g (4-methoxy-6-methylpyrimidin-2-yl)phenylcarbamate and 172 μL 1,8-diazabicyclo[5.4.0]undec-7-ene. After stirring at 20° C. for 30 minutes, 25 mL water was added and the product precipitated by addition of 1N hydrochloric acid, and purified by washing with water, butyl chloride and ether; yield 0.17 g; m.p. 112°-113° C.

NMR (CDCl₃) 13.50 δ, br s, 1H, NH; 8.23 δ, s, 1H, thiophene; 7.40 δ, br s, 1H, NH; 6.32 δ, s, 1H, pyrimidine; 4.01 δ, s, 3H, OCH₃ ; 3.86 δ, s, 3H, COOCH₃ ; 3.7-3.5 δ, m, 1H, S(O)H_(a) H_(b) ; 3.1-2.9 δ, m, 1H, S(O)CH_(a) H_(b) ; 2.49 δ, s, 3H, CH₃ ; 2.0-1.6 δ, m, 2H, --CH₂ --; and 1.09 δ, t, J=7 Hz, 3H, CH₃.

Following the procedures described earlier and exemplified in Examples 1-18, one skilled in the art can prepare the compounds of Tables Ia-XIa and Ib-XVb.

    ______________________________________                                         General                                                                        Formula                                                                        ______________________________________                                         General Formulas for Tables Ia-XIa                                             Ia                                                                                     ##STR70##                                                              IIa                                                                                    ##STR71##                                                              IIIa                                                                                   ##STR72##                                                              IVa                                                                                    ##STR73##                                                              Va                                                                                     ##STR74##                                                              VIa                                                                                    ##STR75##                                                              VIIa                                                                                   ##STR76##                                                              VIIIa                                                                                  ##STR77##                                                              IXa                                                                                    ##STR78##                                                              Xa                                                                                     ##STR79##                                                              XIa                                                                                    ##STR80##                                                              ______________________________________                                         General Formulas for Tables Ib-XIb                                             Ib                                                                                     ##STR81##                                                              IIb                                                                                    ##STR82##                                                              IIIb                                                                                   ##STR83##                                                              IVb                                                                                    ##STR84##                                                              Vb                                                                                     ##STR85##                                                              VIb                                                                                    ##STR86##                                                              VIIb                                                                                   ##STR87##                                                              VIIIb                                                                                  ##STR88##                                                              IXb                                                                                    ##STR89##                                                              Xb                                                                                     ##STR90##                                                              XIb                                                                                    ##STR91##                                                              XIIb                                                                                   ##STR92##                                                              XIIIb                                                                                  ##STR93##                                                              XIVb                                                                                   ##STR94##                                                              XVb                                                                                    ##STR95##                                                              ______________________________________                                    

                                      TABLE Ia                                     __________________________________________________________________________     General Formula Ia                                                             R  R.sub.1                                                                            R.sub.x                                                                          Q.sub.1      X     Y      Z  m.p. (°C.)                        __________________________________________________________________________     H  H   H S(CH.sub.2).sub.2 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 OCH.sub.3                                                                 Cl    OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.3 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.3 OCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 OCH.sub.2 CN                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 OCH.sub.2 CN                                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 SCH.sub.3                                                                 CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H S(CH.sub.2).sub.2 SCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 SCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub. 2 SCH.sub.3                                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              Cl    OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                     Cl    OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 Cl    OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.3 SO.sub.2 N(CH.sub.3).sub.2                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 C(O)CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 C(O)CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 CN                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 CN                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 CN                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  4-CH.sub.3                                                                         H S(CH.sub. 2).sub.2 C(O)N(CH.sub.3).sub.2                                                    CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  4-CH.sub.3                                                                         H S(CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-CH.sub.3                                                                         H S(CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                     CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 Cl                                                                        Cl    OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.3 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.3 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.3 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 F                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 F                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 Br                                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H S(CH.sub.2).sub.2 Br                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H SCHClCHCH.sub.2                                                                             CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H SCHClCHCH.sub.2                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H SCHClCHCH.sub.2                                                                             CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SCH.sub.2 CCH                                                                               CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 CCH                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SCH.sub.2 CCH                                                                               CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H S(CH.sub.2).sub.2 CCH                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 CCH                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H S(CH.sub.2).sub.2 CCH                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  4-Cl                                                                               H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 CH.sub.2 OCH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 CH.sub.2 OCH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 S(O)CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 S(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 CO.sub.2 CH.sub.3                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 CO.sub.2 CH.sub.3                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                             OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                             CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 Br                                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 Br                                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 CH.sub.2 F                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 CH.sub.2 F                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 CHClCHCH.sub.2                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 CHClCHCH.sub.2                                                                     CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  4-CH.sub.3                                                                         H SO.sub.2 CH.sub.2 CCH                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-CH.sub.3                                                                         H SO.sub.2 CH.sub.2 CCH                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H SO.sub.2 (CH.sub.2).sub.2 CCH                                                               CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 CCH                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 (CH.sub.2).sub.2 CCH                                                               CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 P(O)(OCH.sub.3).sub.2                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 P(O)(OCH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H P(O)(OCH.sub.3).sub.2                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H P(O)(OCH.sub.3).sub.2                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H P(O)(SCH.sub.3).sub.2                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H CH.sub.2 OH  CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  4-Cl                                                                               H CH.sub.2 OH  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H CH.sub.2 OH  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H CH.sub.2 OH  Cl    OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H CH.sub.2 OH  CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  4-Cl                                                                               H CH.sub.2 OH  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 OH                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 OH                                                                         Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 OH                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub. 3                                                                            CH                                          H  H   H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 OCH.sub.3                                                                          Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH 135.5-137                                H  H   H (CH.sub.2).sub.2 OCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH 168.5-171                                H  H   H (CH.sub.2).sub.2 OCH.sub.3                                                                  Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N  146.5-147.5                              H  H   H (CH.sub.2).sub.2 OCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             N  145-148                                  H  H   H (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH   147-148.5                              H  H   H (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub. 2).sub.2 OCH.sub.2 CH.sub.3                                                        Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH 128-130                                  H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 SCH.sub.3                                                                  Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.3 SCH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.3 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.3 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.3 SCH.sub.3                                                                  Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.3 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.3 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 S(O)CH.sub.3                                                                       Cl    OCH.sub. 3                                                                            CH                                          H  H   H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      OCH.sub. 3                                                                           OCH.sub.3                                                                             N                                           H  4-CH.sub.3                                                                         H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  4-CH.sub.3                                                                         H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  4-CH.sub.3                                                                         H CH.sub.2 SO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-CH.sub.3                                                                         H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.3 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.3 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.3 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 CO.sub.2 CH.sub.3                                                                  Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  4-Cl                                                                               H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                CH.sub. 3                                                                            OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 C(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 C(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 C(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  4-Cl                                                                               H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  4-Cl                                                                               H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 CN  CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 CN  CH.sub.3                                                                             OCH.sub.3                                                                             CH 127-138                                  H  H   H CH.sub.2 CN  OCH.sub.3                                                                            OCH.sub.3                                                                             CH   189-191.5                              H  H   H CH.sub.2 CN  Cl    OCH.sub.3                                                                             CH 181-183                                  H  H   H CH.sub.2 CN  CH.sub.3                                                                             OCH.sub.3                                                                             N  155.5-159                                H  H   H CH.sub.2 CN  CH.sub.3                                                                             CH.sub.3                                                                              N  173-176                                  H  H   H CH.sub.2 CN  OCH.sub.3                                                                            OCH.sub.3                                                                             N  167.5-169                                H  H   H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             OCH.sub. 3                                                                            CH                                          H  H   H (CH.sub.2).sub.2 CN                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 CN                                                                         Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 CN                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 C(O)N(CH.sub.2).sub.2                                                      CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 Cl  CH.sub.3                                                                             CH.sub.3                                                                              CH 152-154                                  H  H   H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                             CH 155-156                                  H  H   H CH.sub.2 Cl  OCH.sub.3                                                                            OCH.sub.3                                                                             CH 183-184                                  H  H   H CH.sub.2 Cl  Cl    OCH.sub.3                                                                             CH 168-170                                  H  H   H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                             N  150-152                                  H  H   H CH.sub.2 Cl  OCH.sub.3                                                                            OCH.sub.3                                                                             N  108-110                                  H  H   H CH.sub.2 Cl  CH.sub.3                                                                             CH.sub.3                                                                              N  141-146                                  CH.sub.3                                                                          H   H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                             N  125-129                                  H  H   H (CH.sub.2).sub.2 Cl                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 Cl                                                                         Cl    OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 Cl                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 Cl                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 F   CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 F   CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 F   OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 F   Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 F   CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 F   OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 F                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 F                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 F                                                                          CH.sub.3                                                                             OCH.sub. 3                                                                            N                                           H  H   H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3                                                                              CH                                          H  H   H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 Br  Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             N                                           H  H   H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                           H  H   H (CH.sub.2).sub.2 Br                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 Br                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H (CH.sub.2).sub.2 Br                                                                         Cl    OCH.sub.3                                                                             CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                       CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                       N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                            N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCF.sub.2 H                                                                          C.sub.2 H.sub.5                                                                       CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCF.sub.2 H                                                                          CH.sub.2 OCH.sub.3                                                                    CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                       CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                       N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                            N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             C.sub.2 H.sub.5                                                                       N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             NHCH.sub.3                                                                            N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                   N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                       CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                       N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                    CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                    N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                            N                                           H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                   CH                                          H  H   H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                   N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                       CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                       N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                            CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                            N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCF.sub.2 H                                                                          C.sub.2 H.sub.5                                                                       CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCF.sub.2 H                                                                          CH.sub.2 OCH.sub.3                                                                    CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCF.sub.2 H                                                                          NHCH.sub.3                                                                            CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                       CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                            CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                            N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          Cl    NHCH.sub.3                                                                            CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             C.sub.2 H.sub.5                                                                       CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             C.sub.2 H.sub.5                                                                       N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          Cl    NHCH.sub.3                                                                            CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             C.sub.2 H.sub.5                                                                       CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             C.sub.2 H.sub.5                                                                       N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             NHCH.sub.3                                                                            N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                   CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                   N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                       CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                       N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                    CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                    N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                            CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                            N                                           H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                   CH                                          H  4-Cl                                                                               H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                   N                                           H  H   H CN           CH.sub.3                                                                             CH.sub.3                                                                              CH 165-167                                  H  H   H CN           CH.sub.3                                                                             OCH.sub.3                                                                             CH 166-168                                  H  H   H CN           OCH.sub.3                                                                            OCH.sub.3                                                                             CH 188-190                                  H  H   H CN           Cl    OCH.sub.3                                                                             CH 169-171                                  H  H   H CN           CH.sub.3                                                                             OCH.sub.3                                                                             N  150-152                                  H  H   H CN           OCH.sub.3                                                                            OCH.sub.3                                                                             N  176-178                                  H  H   H SO.sub.2 NHCH.sub.3                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H                                                                                 ##STR96##   OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          H  H   H SO.sub.2 NHC.sub.6 H.sub.5                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                          __________________________________________________________________________

                                      TABLE IIa                                    __________________________________________________________________________     General Formula IIa                                                            R  R.sub.1  R.sub.x                                                                          Q.sub.1      X     Y        Z  m.p. (°C.)                 __________________________________________________________________________     H  H        H S(CH.sub.2).sub.2 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 OCH.sub.3                                                                 Cl    OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.3 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.3 OCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 OCH.sub.2 CN                                                              OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 OCH.sub.2 CN                                                              CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 SCH.sub.3                                                                 CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H S(CH.sub.2).sub.2 SCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 SCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 SCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              Cl    OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                     Cl    OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 OCH.sub. 3                                                                           OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 Cl    OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.3 SO.sub.2 N(CH.sub.3).sub.2                                                OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                       CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                       OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 C(O)CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 C(O)CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 CN                                                                        CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H S(CH.sub.2).sub.2 CN                                                                        CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 CN                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 CN                                                                        CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 C(O)N(CH.sub.3 ).sub.2                                                            CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H S(CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                     CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H S(CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                     OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 Cl                                                                        Cl    OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.3 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.3 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.3 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 F                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 F                                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 Br                                                                        CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H S(CH.sub. 2).sub.2 Br                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  5-Cl     H S--CHClCH═CH.sub.2                                                                      CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  5-Cl     H S--CHClCH═CH.sub.2                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  5-Cl     H S--CHClCH═CH.sub.2                                                                      CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SCH.sub.2 C.tbd.CH                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 C.tbd.CH                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SCH.sub.2 C.tbd.CH                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H S(CH.sub.2).sub.2 C.tbd.CH                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 C.tbd.CH                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H S(CH.sub.2).sub.2 C.tbd.CH                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  5-Cl     H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  5-Cl     H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 CH.sub.2 OCH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 CH.sub.2 OCH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                OCH.sub. 3                                                                           OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 S(O)CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 S(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 CO.sub.2 CH.sub.3                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 CO.sub.2 CH.sub.3                                                 CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                             OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                             CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 Br                                                                OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 Br                                                                CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 CH.sub.2 F                                                                         CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H SO.sub.2 CH.sub.2 F                                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 CHClCH═CH.sub.2                                                                OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 CHClCH═CH.sub.2                                                                CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  5-CH.sub.3                                                                              H SO.sub.2 CH.sub.2 C.tbd.CH                                                                  OCH.sub. 3                                                                           OCH.sub.3                                                                               CH                                   H  5-CH.sub.3                                                                              H SO.sub.2 CH.sub.2 C.tbd.CH                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H SO.sub.2 (CH.sub.2).sub.2 C.tbd.CH                                                          CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 C.tbd.CH                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H SO.sub.2 (CH.sub.2).sub.2 C.tbd.CH                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 P(O)(OCH.sub.3).sub.2                                                              OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 P(O)(OCH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H P(O)(OCH.sub.3).sub.2                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H P(O)(OCH.sub.3).sub.2                                                                       CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H P(O)(SCH.sub.3).sub.2                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H P(O)(SCH.sub.3).sub.2                                                                       CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  5-Cl     H CH.sub.2 OH  CH.sub.3                                                                             CH.sub.3 CH                                   H  5-Cl     H CH.sub.2 OH  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  5-Cl     H CH.sub.2 OH  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  5-Cl     H CH.sub.2 OH  Cl    OCH.sub.3                                                                               CH                                   H  5-Cl     H CH.sub.2 OH  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  5-Cl     H CH.sub.2 OH  OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 OH                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 OH                                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 OH                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3 CH 175-177                           H  H        H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               CH 171-173                           H  H        H CH.sub.2 OCH.sub.3                                                                          Cl    OCH.sub.3                                                                               CH 154-155                           H  H        H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N  155-156                           H  H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               N  158                               H  H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH 143-146                           H  H        H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 Cl    OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 O(CH.sub.2 ).sub.2 CN                                                              OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               CH 155-159(d)                        H  H        H CH.sub.2 SCH.sub.3                                                                          Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.3 SCH.sub. 3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 S(O)CH.sub.3                                                                       Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          OCH.sub. 3                                                                           OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.3 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.3 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  5-Cl     H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3 ).sub.2                                                CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  5-Cl     H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  5-Cl     H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                 CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 C(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 C(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 C(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  5-Cl     H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  5-Cl     H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  5-Cl     H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 CN  CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 CN  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CN  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CN  Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 CN  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 CN  OCH.sub.3                                                                            OCH.sub.3                                                                               N  105-110                           H  H        H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 CN                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 CN                                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 CN                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                      CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                      OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                      CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 Cl  CH.sub.3                                                                             CH.sub.3 CH 186-187                           H  H        H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                               CH 161.5-163                         H  H        H CH.sub.2 Cl  OCH.sub.3                                                                            OCH.sub.3                                                                               CH 175-177                           H  H        H CH.sub.2 Cl  Cl    OCH.sub.3                                                                               CH 165-167                           H  H        H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                               N  158-159                           H  H        H CH.sub.2 Cl  OCH.sub.3                                                                            OCH.sub.3                                                                               N  140-143                           H  H        H CH.sub.2 Cl  CH.sub.3                                                                             CH.sub.3 N  175.5-177                         H  H        H (CH.sub.2).sub.2 Cl                                                                         CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H (CH.sub.2).sub.2 Cl                                                                         CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 Cl                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 Cl                                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 Cl                                                                         CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 Cl                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 F   CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 F   CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 F   OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 F   Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 F   CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 F   OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 F                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 F                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 F                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 Br  Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  H        H (CH.sub.2).sub.2 Br                                                                         CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 Br                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H (CH.sub.2).sub.2 Br                                                                         Cl    OCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                         CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                         N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                      CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                      N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                              N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                     CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCF.sub.2 H                                                                          C.sub.2 H.sub.5                                                                         CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCF.sub.2 H                                                                          CH.sub.2 OCH.sub.3                                                                      CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                         CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                         N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                      CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                      N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                              N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                     N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             C.sub.2 H.sub.5                                                                         N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                      CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                      N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             NHCH.sub.3                                                                              N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                     N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                         CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                         N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                      CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                      N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                              N                                    H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                     CH                                   H  H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                     N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                         CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                         N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                      CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                      N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                              CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                              N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                     CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                     N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCF.sub.2 H                                                                          C.sub.2 H.sub.5                                                                         CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCF.sub.2 H                                                                          CH.sub.2 OCH.sub.3                                                                      CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCF.sub.2 H                                                                          NHCH.sub.3                                                                              CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                         CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                      N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                              CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                              N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub. 2 CF.sub.3                                                                  CH(OCH.sub.3).sub.2                                                                     CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                     N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          Cl    NHCH.sub.3                                                                              CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             C.sub.2 H.sub.5                                                                         CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                      CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                      N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          Cl    NHCH.sub.3                                                                              CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                      CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                      N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             NHCH.sub.3                                                                              N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                     CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                     N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                         CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                         N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                      CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                      N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                              CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                              N                                    H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                     CH                                   H  5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                     N                                    H  H        H CN           CH.sub.3                                                                             CH.sub.3 CH                                   H  H        H CN           CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  H        H CN           OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  H        H CN           Cl    OCH.sub.3                                                                               CH                                   H  H        H CN           CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CN           OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    CH.sub.3                                                                          H        H CN           CH.sub.3                                                                             OCH.sub.3                                                                               N                                    CH.sub.3                                                                          H        H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N                                    CH.sub.3                                                                          H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            SCF.sub.2 H                                                                             CH                                   H  H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            SCH.sub.3                                                                               CH                                   H  H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.2 C.tbd.CH                                                                      CH                                   H  H        H CH.sub.2 OCH.sub. 3                                                                         OCH.sub.3                                                                            OCH.sub.2 CH═CH.sub.2                                                               CH                                   H  H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 SCH.sub.3                                                                      CH                                   H  H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CN       CH                                   H  4-SCH.sub.2 CH.sub.3                                                                    H CN           CH.sub.3                                                                             CH.sub.3 CH                                   H  4-SCH.sub.2 CH.sub.3                                                                    H CN           CH.sub.3                                                                             OCH.sub.3                                                                               CH 231-236                           H  4-SCH.sub.2 CH.sub.3                                                                    H CN           OCH.sub.3                                                                            OCH.sub.3                                                                               CH 215-221                           H  4-SCH.sub.2 CH.sub.3                                                                    H CN           CH.sub.3                                                                             OCH.sub.3                                                                               N  203-207                           H  4-SCH.sub.2 CH.sub.3                                                                    H CN           OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-SCH.sub.2 CH.sub.3                                                                    H CN           Cl    OCH.sub.3                                                                               CH 217-220                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                           H CN           CH.sub.3                                                                             CH.sub.3 CH                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                           H CN           CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                           H CN           OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                           H CN           CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                           H CN           OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                           H CN           Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub. 2 S(O).sub.2 CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                               CH 173-176                           H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                               CH 160-164                           H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                               CH 98-105                            H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                               CH 138-142                           H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             OCH.sub.3                                                                               CH 109-112                           H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                               CH 123-127                           H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             OCH.sub.3                                                                               N  158-161                           H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub. 2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 Cl  CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                               CH 195-200                           H  4-CH.sub.3                                                                              H CH.sub.2 Cl  OCH.sub.3                                                                            OCH.sub.3                                                                               CH 134-140                           H  4-CH.sub.3                                                                              H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 Cl  OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 Cl  Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 Br  Cl    OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 F   CH.sub.3                                                                             CH.sub.3 CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 F   CH.sub.3                                                                             OCH.sub. 3                                                                              CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 F   OCH.sub.3                                                                            OCH.sub.3                                                                               CH                                   H  4-CH.sub.3                                                                              H CH.sub.2 F   CH.sub.3                                                                             OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 F   OCH.sub.3                                                                            OCH.sub.3                                                                               N                                    H  4-CH.sub.3                                                                              H CH.sub.2 F   Cl    OCH.sub.3                                                                               CH                                   __________________________________________________________________________

                                      TABLE IIIa                                   __________________________________________________________________________     General Formula IIIa                                                           R R.sub.1  R.sub.x                                                                          Q.sub.1      X     Y      Z  m.p. (°C.)                    __________________________________________________________________________     H H        H S(CH.sub.2).sub.2 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OCH.sub.3                                                                 Cl    OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.3 OCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.3 OCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OCH.sub.2 CN                                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OCH.sub.2 CN                                                              Cl    OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OCH.sub.2 CN                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 SCH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 SCH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub. 2 SCH.sub.3                                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              Cl    OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 S(O)CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                     Cl    OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H SCH.sub.2 CO.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H S(CH.sub.2).sub.3 SO.sub.2 N(CH.sub.3).sub.2                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.3 SO.sub.2 N(CH.sub.3).sub.2                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SCH.sub.2 C(O)CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SCH.sub.2 C(O)CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 CN                                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H S(CH.sub.2).sub.2 CN                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 CN                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 CN                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SCH.sub.2 C(O)N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H S(CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                     CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H S(CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 Cl                                                                        Cl    OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.3 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.3 Cl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.3 Cl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 F                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 F                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 Br                                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H S(CH.sub.2).sub.2 Br                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 Br                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 5-Cl     H S--CHClCH═CH.sub.2                                                                      CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 5-Cl     H S--CHClCH═CH.sub.2                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 5-Cl     H S--CHClCH═CH.sub.2                                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SCH.sub.2 C.tbd.CH                                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H SCH.sub.2 C.tbd.CH                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H SCH.sub.2 C.tbd.CH                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SCH.sub.2 C.tbd.CH                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 C.tbd.CH                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 C.tbd.CH                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 C.tbd.CH                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 5-Cl     H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 5-Cl     H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 CH.sub.2 OCH.sub.2 CH.sub. 3                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 CH.sub.2 OCH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 OCH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 SCH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 (CH.sub.2).sub.2 S(O)CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 S(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 (CH.sub.2).sub. 2 CO.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 CO.sub.2 CH.sub.3                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 CO.sub.2 CH.sub.3                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 C(O)CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                             OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                             CH.sub.3                                                                             OCH.sub. 3                                                                            N                                       H H        H SO.sub.2 (CH.sub.2).sub.2 Br                                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 Br                                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 CH.sub.2 F                                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H SO.sub.2 CH.sub.2 F                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 CH.sub.2 F                                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 CH.sub.2 F                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 CHClCH═CH.sub.2                                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H SO.sub.2 CH.sub.2 C.tbd.CH                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H SO.sub.2 CH.sub.2 C.tbd.CH                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H SO.sub.2 (CH.sub.2).sub.2 C.tbd.CH                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 C.tbd.CH                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H SO.sub.2 (CH.sub.2).sub.2 C.tbd.CH                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 P(O)(OCH.sub.3).sub.2                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 P(O)(OCH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub. 3                                                                            N                                       H H        H CH.sub.2 P(O)(OCH.sub.3).sub.2                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H P(O)(OCH.sub.3).sub.2                                                                       Cl    OCH.sub.3                                                                             CH                                      H H        H P(O)(SCH.sub.3).sub.2                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H P(O)(SCH.sub.3).sub.2                                                                       Cl    OCH.sub.3                                                                             CH                                      H H        H P(O)(SCH.sub.3).sub.2                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-Cl     H CH.sub.2 OH  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-Cl     H CH.sub.2 OH  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-Cl     H CH.sub.2 OH  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-Cl     H CH.sub.2 OH  Cl    OCH.sub.3                                                                             CH                                      H 2-Cl     H CH.sub.2 OH  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-Cl     H CH.sub.2 OH  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 OH                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 OH                                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 OH                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 OH                                                                         OCH.sub. 3                                                                           OCH.sub.3                                                                             N                                       H H        H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 OCH.sub.3                                                                          Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 OCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 5-CH.sub.3                                                                              H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 5-CH.sub.3                                                                              H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 5-CH.sub.3                                                                              H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 5-CH.sub.3                                                                              H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 Cl    OCH.sub.3                                                                             CH                                      H 5-CH.sub.3                                                                              H CH.sub.2 OCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 O(CH.sub.2).sub.2 CN                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 SCH.sub. 3                                                                 CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 SCH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.3 SCH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 S(O)CH.sub. 3                                                                      Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 S(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 S(O)CH.sub.2 CH.sub.3                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 5-CH.sub.3                                                                              H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 5-CH.sub.3                                                                              H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 5-CH.sub.3                                                                              H CH.sub.2 SO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 5-CH.sub.3                                                                              H CH.sub.2 SO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.3 SO.sub.2 CH.sub.3                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.3 SO.sub.2 CH.sub.3                                                          Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CO.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CO.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 5-Cl     H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 5-Cl     H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 5-Cl     H (CH.sub.2).sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 C(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 C(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 C(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-Cl     H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-Cl     H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-Cl     H (CH.sub.2).sub.2 C(O)CH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 CN  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 CN  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CN  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CN  Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 CN  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 CN  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 CN                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 CN                                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 CN                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 CN                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 C(O)N(CH.sub.3).sub.2                                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                      CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 C(O)N(CH.sub.3).sub.2                                                      CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 Cl  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 Cl  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 Cl  Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 Cl  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 Cl  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 Cl                                                                         CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H (CH.sub.2).sub.2 Cl                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 Cl                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 Cl                                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 Cl                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 Cl                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H CH.sub.2 F   CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 F   CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 F   OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 F   Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 F   CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 F   OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 F                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 F                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 F                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 Br  Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H (CH.sub.2).sub.2 Br                                                                         CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 Br                                                                         OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H (CH.sub.2).sub.2 Br                                                                         Cl    OCH.sub.3                                                                             CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                       CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                       N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                            N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   CH                                      H H        H CH.sub.2 SCH.sub. 3                                                                         OCF.sub.2 H                                                                          C.sub.2 H.sub.5                                                                       CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCF.sub.2 H                                                                          CH.sub.2 OCH.sub.3                                                                    CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                       CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                       N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                            N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   N                                       H H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    N                                       H H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             NHCH.sub.3                                                                            N                                       H H        H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                   N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                       CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                       N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                    CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                    N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                            N                                       H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                   CH                                      H H        H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                   N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                       CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   C.sub.2 H.sub.5                                                                       N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                            CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                            N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CH.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCF.sub. 2 H                                                                         C.sub.2 H.sub.5                                                                       CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCF.sub.2 H                                                                          CH.sub.2 OCH.sub.3                                                                    CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCF.sub.2 H                                                                          NHCH.sub.3                                                                            CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   C.sub.2 H.sub.5                                                                       CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH.sub.2 OCH.sub.3                                                                    N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                            CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   NHCH.sub.3                                                                            N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                   CH(OCH.sub.3).sub.2                                                                   N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          Cl    NHCH.sub.3                                                                            CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             C.sub.2 H.sub.5                                                                       CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          Cl    NHCH.sub.3                                                                            CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.2 OCH.sub.3                                                                    N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             NHCH.sub.3                                                                            N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                   CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          CH.sub.3                                                                             CH(OCH.sub.3).sub.2                                                                   N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                       CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            C.sub.2 H.sub.5                                                                       N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                    CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH.sub.2 OCH.sub.3                                                                    N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                            CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            NHCH.sub.3                                                                            N                                       H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                   CH                                      H 5-Cl     H CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                            CH(OCH.sub.3).sub.2                                                                   N                                       H H        H CN           OCH.sub.3                                                                            CH.sub.3                                                                              N                                       H H        H CN           OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CN           CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CN           CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CN           OCH.sub.3                                                                            OCH.sub.3                                                                             CH 191-192                              H 2-CH.sub.3                                                                              H CN           CH.sub.3                                                                             OCH.sub.3                                                                             N  183-187                              H 2-CH.sub.3                                                                              H CN           OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CN           Cl    OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OH                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 OH                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 OH                                                                        Cl    OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H H        H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OH                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H H        H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 OH                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H H        H S(CH.sub.2).sub.2 OH                                                                        Cl    OCH.sub. 3                                                                            CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H S(CH.sub.2).sub.2 OH                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H S(CH.sub.2).sub.2 OH                                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H S(CH.sub.2).sub.2 OH                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H S(CH.sub.2).sub.2 OH                                                                        Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.3                                                                          Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.3                                                                       Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.3                                                                Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub. 3                                                                            N                                       H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.3                                                                      Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.3                                                             OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.3                                                             OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.3                                                             Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.2 CH.sub.3                                                    CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.2 CH.sub.3                                                    CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S-- CH.sub.2 CH.sub.2 CH.sub.3                                                   OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.2 CH.sub.3                                                    CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.2 CH.sub.3                                                    OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 --S--CH.sub.2 CH.sub.2 CH.sub.3                                                    Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             CH 218-223                              H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             CH 193-199                              H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             N  151-156                              H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.3                                                                              H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub. 3                                                                             H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.3                                                                              H CH.sub.2 Br  Cl    OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CH.sub.2 CH.sub.3                                                                     H CH.sub.2 Br  Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.2 CH.sub.3                                                            H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.2 CH.sub.3                                                            H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.2 CH.sub.3                                                            H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.2 CH.sub.3                                                            H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.2 CH.sub.3                                                            H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub. 2 CH.sub.3                                                           H CH.sub.2 Br  Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH(CH.sub.3).sub.2                                                           H CH.sub.2 Br  CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH(CH.sub.3).sub.2                                                           H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH(CH.sub.3).sub.2                                                           H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH(CH.sub.3).sub.2                                                           H CH.sub.2 Br  CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH(CH.sub.3).sub.2                                                           H CH.sub.2 Br  OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH(CH.sub.3).sub.2                                                           H CH.sub.2 Br  Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.3                                                                          Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.3                                                                       Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.3                                                                CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.3                                                                CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.3                                                                OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.3                                                                CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.3                                                                OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.3                                                                Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             CH.sub. 3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.3                                                                 Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.3                                                              Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub. 3                                                      CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.3                                                       Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 SCH.sub.2 CH.sub.2 CH.sub.3                                                        Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                     Cl    OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                             CH.sub.3                                                                              CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                             OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                      H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub. 2 CH.sub.2 CH.sub.3                                             CH.sub.3                                                                             OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              OCH.sub.3                                                                            OCH.sub.3                                                                             N                                       H 2-CO.sub.2 CH.sub.3                                                                     H CH.sub.2 S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              Cl    OCH.sub.3                                                                             CH                                      __________________________________________________________________________

                  TABLE IVa                                                        ______________________________________                                         General Formula IVa                                                            R    R.sub.1                                                                              R.sub.x                                                                              Q.sub.1    X.sub.1                                                                               Y.sub.1                                                                             m.p. (°C.)                      ______________________________________                                         H    H     H     CH.sub.2 OCH.sub.3                                                                        CH.sub.3                                                                              O                                           H    H     H     CH.sub.2 OCH.sub.3                                                                        OCH.sub.3                                                                             O                                           H    H     H     CH.sub.2 OCH.sub.3                                                                        OC.sub.2 H.sub.5                                                                      O                                           H    H     H     CH.sub.2 OCH.sub.3                                                                        OCF.sub.2 H                                                                           O                                           H    H     H     CH.sub.2 OCH.sub.3                                                                        CH.sub.3                                                                              CH.sub.2                                    H    H     H     CH.sub.2 OCH.sub.3                                                                        OCH.sub.3                                                                             CH.sub.2                                    H    H     H     CH.sub.2 OCH.sub.3                                                                        OC.sub.2 H.sub.5                                                                      CH.sub.2                                    H    H     H     CH.sub.2 OCH.sub.3                                                                        OCF.sub.2 H                                                                           CH.sub.2                                    H    H     H     SCH.sub.2 CH.sub.2 OCH.sub.3                                                              OCH.sub.3                                                                             O                                           H    H     H     SCH.sub.2 CH.sub.2 OCH.sub.3                                                              CH.sub.3                                                                              O                                           H    H     H     S(CH.sub.2).sub.3 Cl                                                                      CH.sub.3                                                                              O                                           H    H     H     S(CH.sub.2).sub.3 Cl                                                                      OCH.sub.3                                                                             O                                           H    H     H     SCH.sub.2 C.tbd.CH                                                                        OCH.sub.3                                                                             O                                           H    H     H     SCH.sub.2 C.tbd.CH                                                                        CH.sub.3                                                                              O                                           H    H     H     CH.sub.2 Cl                                                                               OCH.sub.3                                                                             O                                           H    H     H     CHClCH.sub.3                                                                              OCH.sub.3                                                                             O                                           ______________________________________                                    

                  TABLE Va                                                         ______________________________________                                         General Formula Va                                                             R    R.sub.1                                                                               R.sub.x                                                                              Q.sub.1     X.sub.1 m.p. (°C.)                        ______________________________________                                         H    H      H     SCH.sub.2 CH═CH.sub.2                                                                  CH.sub.3                                         H    H      H     SCH.sub.2 CH═CH.sub.2                                                                  OCH.sub.3                                        H    H      H     SCH.sub.2 CH═CH.sub.2                                                                  OCF.sub.2 H                                      H    H      H     CH.sub.2 OCH.sub.3                                                                         OCH.sub.3                                        H    H      H     CH.sub.2 OCH.sub.3                                                                         CH.sub.3                                         H    H      H     S(CH.sub.2).sub.2 SCH.sub.3                                                                OCH.sub.3                                        H    H      H     S(CH.sub.2).sub.2 SCH.sub.3                                                                CH.sub.3                                         H    H      H     O(CH.sub.2).sub.2 OCH.sub.3                                                                OCH.sub.3                                        H    H      H     O(CH.sub.2).sub.2 OCH.sub.3                                                                CH.sub.3                                         ______________________________________                                    

                  TABLE VIa                                                        ______________________________________                                         General Formula VIa                                                            R    R.sub.1                                                                              R.sub.x                                                                              Q.sub.1    X.sub.1                                                                               Y.sub.2                                                                             m.p. (°C.)                      ______________________________________                                         H    H     H     S(CH.sub.2).sub.2 SCH.sub.3                                                               CH.sub.3                                                                              H                                           H    H     H     S(CH.sub.2).sub.2 SCH.sub.3                                                               OCH.sub.3                                                                             H                                           H    H     H     S(CH.sub.2).sub.2 SCH.sub.3                                                               OC.sub.2 H.sub.5                                                                      H                                           H    H     H     S(CH.sub.2).sub.2 SCH.sub.3                                                               OCF.sub.2 H                                                                           H                                           H    H     H     S(CH.sub.2).sub.2 SCH.sub.3                                                               CH.sub.3                                                                              CH.sub.3                                    H    H     H     S(CH.sub.2).sub.2 SCH.sub.3                                                               OCH.sub.3                                                                             CH.sub.3                                    H    H     H     S(CH.sub.2).sub.2 SCH.sub.3                                                               OC.sub.2 H.sub.5                                                                      CH.sub.3                                    H    H     H     S(CH.sub.2).sub.2 SCH.sub.3                                                               OCF.sub.2 H                                                                           CH.sub.3                                    H    H     H     S(CH.sub.2).sub.3 Cl                                                                      OCH.sub.3                                                                             H                                           H    H     H     S(CH.sub.2).sub.3 Cl                                                                      CH.sub.3                                                                              H                                           H    H     H     SCH.sub.2 CO.sub.2 CH.sub.3                                                               OCH.sub.3                                                                             H                                           H    H     H     SCH.sub.2 CO.sub.2 CH.sub.3                                                               CH.sub.3                                                                              H                                           H    H     H     SO.sub.2 CH.sub.2 C.tbd.CH                                                                OCH.sub.3                                                                             H                                           H    H     H     SO.sub.2 CH.sub.2 C.tbd.CH                                                                CH.sub.3                                                                              H                                           ______________________________________                                    

                  TABLE VIIa                                                       ______________________________________                                         General Formula VIIa                                                           R    R.sub.1                                                                              R.sub.x                                                                              Q.sub.1   X.sub.2                                                                              Y.sub.3                                                                               m.p. (°C.)                      ______________________________________                                         H    H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             CH.sub.3                                      H    H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               OCH.sub.3                                                                            CH.sub.3                                      H    H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               SCH.sub.3                                                                            CH.sub.3                                      H    H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             CH.sub.2 CH.sub.3                             H    H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               SCH.sub.3                                                                            CH.sub.2 CH.sub.3                             H    H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               SCH.sub.3                                                                            CH.sub.2 CF.sub.3                             H    H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             CH.sub.2 CF.sub.3                             H    H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               OCH.sub.3                                                                            CH.sub.2 CF.sub.3                             H    H     H     CH.sub.2 CN                                                                              SCH.sub.3                                                                            CH.sub.2 CH.sub.3                             H    H     H     CH.sub.2 CN                                                                              OCH.sub.3                                                                            CH.sub.3                                      ______________________________________                                    

                  TABLE VIIIa                                                      ______________________________________                                         General Formula VIIIa                                                          R    R.sub.1                                                                               R.sub.x                                                                               Q.sub.1     X.sub.3                                                                               m.p. (°C.)                        ______________________________________                                         H    H      H      CH.sub.2 OCH.sub.3                                                                         CH.sub.3                                        H    H      H      CH.sub.2 OCH.sub.3                                                                         OCH.sub.3                                       H    H      H      S(CH.sub.2).sub.2 SCH.sub.3                                                                OCH.sub.3                                       H    H      H      SCH.sub.2 CO.sub.2 CH.sub.3                                                                OCH.sub.3                                       H    H      H      (CH.sub.2).sub.2 Br                                                                        OCH.sub.3                                       H    H      H      CH.sub.2 F  OCH.sub.3                                       H    H      H      CH.sub.2 CO.sub.2 CH.sub.3                                                                 OCH.sub.3                                       H    H      H      CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2                                                        OCH.sub.3                                       ______________________________________                                    

                  TABLE IXa                                                        ______________________________________                                         General Formula IXa                                                            R   R.sub.1                                                                              R.sub.x                                                                              Q.sub.1   X     Y     Z    m.p. (°C.)                   ______________________________________                                         H   H     H     CH.sub.2 OCH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                            N                                        H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               Cl    OCH.sub.3                                                                            CH                                       H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                            N                                        H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 Cl                                                                              CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 Cl                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 Cl                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 Cl                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 OH                                                                              CH.sub. 3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CN        CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CN        CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CN        Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                            N                                        ______________________________________                                    

                  TABLE Xa                                                         ______________________________________                                         General Formula Xa                                                             R   R.sub.1                                                                              R.sub.x                                                                              Q.sub.1   X     Y     X    m.p. (°C.)                   ______________________________________                                         H   H     H     CH.sub.2 OCH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                            N                                        H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               Cl    OCH.sub.3                                                                            CH                                       H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                            N                                        H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 Cl                                                                              CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 Cl                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 Cl                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 Cl                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 OH                                                                              CH.sub. 3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CN        CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CN        CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CN        Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                            N                                        ______________________________________                                    

                  TABLE XIa                                                        ______________________________________                                         General Formula XIa                                                            R   R.sub.1                                                                              R.sub.x                                                                              Q.sub.1   X     Y     Z    m.p. (°C.)                   ______________________________________                                         H   H     H     CH.sub.2 OCH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OCH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                            N                                        H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               Cl    OCH.sub.3                                                                            CH                                       H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             OCH.sub.3                                                                            N                                        H   H     H     (CH.sub.2).sub.2 OCH.sub.3                                                               CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 Cl                                                                              CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 Cl                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 Cl                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 Cl                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 OH                                                                              CH.sub. 3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 OH                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CN        CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CN        CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CN        Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 CN                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                             CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       Cl    OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                       H   H     H     CH.sub.2 SCH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                            N                                        ______________________________________                                    

                                      TABLE Ib                                     __________________________________________________________________________     General Formula Ib                                                             R  R.sub.1    R.sub.x                                                                          Q.sub.2                                                                               X   Y   Z  m.p. (°C.)                            __________________________________________________________________________     H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub. 2 CH.sub.3                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH 137-140                                      H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH 134-136                                      H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N  147-149                                      H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH 124-129                                      H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub. 3                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.3                                                                       H CO.sub. 2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O.sub.2)N(CH.sub.3).sub.2                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O.sub.2)N(CH.sub.3).sub.2                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O.sub.2)N(CH.sub.3).sub.2                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O.sub.2)N(CH.sub.3).sub.2                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O.sub.2)N(CH.sub.3).sub.2                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O.sub.2)N(CH.sub.3).sub.2                                                             H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              __________________________________________________________________________

                                      TABLE IIb                                    __________________________________________________________________________     General Formula IIb                                                            R  R.sub.1    R.sub.x                                                                          Q.sub.2   X   Y   Z  m.p. (°C.)                         __________________________________________________________________________     H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH 184-186                                   H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N  176-179                                   H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                               ##STR97## H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H                                                                                  ##STR98## H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H                                                                                  ##STR99## H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H                                                                                  ##STR100##                                                                               H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H                                                                                  ##STR101##                                                                               H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H                                                                                  ##STR102##                                                                               H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H CO.sub. 2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH 149-153                                   H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH 148-150                                   H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH  98-100                                   H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N  144-148                                   H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N  136-139                                   H  4-SCH.sub.2 CH.sub. 3                                                                     H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH 126-130                                   H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH 103-105                                   H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH 158-165                                   H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH 203-205                                   H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N  181-184                                   H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N  179-182                                   H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH 157-163                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH 126-130                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH 145-148                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH 151-157                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N  136-142                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub. 3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          N  130-133                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH 158-164                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH 155-162                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH 147-150                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH 139-142                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N  154-164                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N  159-166                                   H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH 139-142                                   H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH 113-114                                   H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH 112-113                                   H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH 178-179                                   H  4-S(O)CH.sub.2 CH.sub. 2 CH.sub.3                                                         H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N  193-194                                   H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N  201-204                                   H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH 187-190                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH 103-106                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH 92-94                                     H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH  96-101                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N  153-161                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.2                                                                          N  153-160                                   H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH 111-113                                   H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub. 2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH 163-167                                   H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH 175-179                                   H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH 183-186                                   H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N  108-112                                   H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N  184-188                                   H  4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        Cl  OCH.sub.3                                                                          CH 186-189                                   H                                                                                  ##STR103##                                                                               Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H                                                                                  ##STR104##                                                                               Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H                                                                                  ##STR105##                                                                               Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H                                                                                  ##STR106##                                                                               Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H                                                                                  ##STR107##                                                                               Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H                                                                                  ##STR108##                                                                               Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.3                                                                            Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub. 2 CH.sub.3                                                                    Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH 161-165                                   H  4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH 162-164                                   H  4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH 165-170                                   H  4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N  112-115                                   H  4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N   97-101                                   H  4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        Cl  OCH.sub.3                                                                          CH 124-128                                   H  4-S(O)CH.sub.2 CH.sub.3                                                                   Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.3                                                                   Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.3                                                                   Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub. 3                                                         Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   Br                                                                               Br        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   Br                                                                               Br        Cl  OCH.sub.3                                                                          CH                                           H  4-SO.sub.2 N(CH.sub.3).sub.2                                                              H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SO.sub.2 N(CH.sub.3).sub.2                                                              H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SO.sub.2 N(CH.sub.3).sub.2                                                              H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SO.sub.2 N(CH.sub.3).sub.2                                                              H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SO.sub.2 N(CH.sub.3).sub.2                                                              H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SO.sub.2 N(CH.sub.3).sub.2                                                              H SO.sub.2 N(CH.sub.3).sub.2                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H SO.sub.2 N(CH.sub.3).sub.2                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H SO.sub.2 N(CH.sub.3).sub.2                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H SO.sub.2 N(CH.sub.3).sub.2                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SO.sub.2 N(CH.sub.3).sub.2                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H SO.sub.2 N(CH.sub.3).sub.2                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-SCH(CH.sub.3).sub.2                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH(CH.sub.3).sub.2                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH(CH.sub.3).sub.2                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH(CH.sub.3).sub.2                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH(CH.sub.3).sub.2                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH(CH.sub.3).sub.2                                                                     H SO.sub.2 N(CH.sub.3).sub.2                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                        Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub. 2 CH.sub.3                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub. 3                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub. 2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub. 2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           OCH.sub.3                                                                          H                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH(CH.sub.3).sub.2                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH(CH.sub.3).sub.2                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub. 3                                                                              H CO.sub.2 CH(CH.sub.3).sub.2                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH(CH.sub.3).sub.2                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH(CH.sub.3).sub.2                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH(CH.sub.3).sub.2                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH(CH.sub.3).sub.2                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH(CH.sub. 3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH(CH.sub.3).sub.2                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 OCH.sub.3                                                     Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub. 2 Cl                                                           CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.2 Cl                                                            Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H                                                                                 ##STR109##                                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H                                                                                 ##STR110##                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H                                                                                 ##STR111##                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H                                                                                 ##STR112##                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H                                                                                 ##STR113##                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H                                                                                 ##STR114##                                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H                                                                                 ##STR115##                                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H                                                                                 ##STR116##                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H                                                                                 ##STR117##                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H                                                                                 ##STR118##                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H                                                                                 ##STR119##                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H                                                                                 ##STR120##                                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H                                                                                 ##STR121##                                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H                                                                                 ##STR122##                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H                                                                                 ##STR123##                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub. 3                                                            H                                                                                 ##STR124##                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H                                                                                 ##STR125##                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H                                                                                 ##STR126##                                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.3                                                                            H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub. 3                                                                         OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.3                                                                   H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.3                                                                   H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.3 CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H SCH.sub.3 Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H SCH.sub. 2 CH.sub.3                                                                      Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.2 CH.sub.3                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.2 CH.sub.3                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub. 3                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                              Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H S(O)CH.sub.2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H S(O)CH.sub.2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H S(O)CH.sub.2 CH.sub.3                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.3                                                                            H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H S(O)CH.sub.2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H S(O)CH.sub.2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H S(O)CH.sub.2 CH.sub.3                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H S(O)CH.sub.2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H S(O)CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H S(O)CH.sub.2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H S(O)CH.sub.2 CH.sub.3                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.2 CH.sub.3                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.2 CH.sub.3                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.2 CH.sub.3                                                             Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.2 CH.sub.3                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.2 CH.sub.3                                                             Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.2 CH.sub.3                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.2 CH.sub.3                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.2 CH.sub.3                                                             Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHO       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CHO       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.3                                                                            H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.3                                                                            H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.3                                                                            H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CHO       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.3                                                                     H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.3                                                                     H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHO       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CHO       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.3                                                                   H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CHO       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CHO       CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CHO       CH.sub. 3                                                                          CH.sub.3                                                                           CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CHO       Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHNOH     CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CHNOH     Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHNOCH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.3                                                                               H CHNOCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHNOCH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.3                                                                               H CHNOCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CHNOCH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.3                                                                               H CHNOCH.sub.3                                                                             Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOCH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOCH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOCH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.3                                                                      H CHNOCH.sub.3                                                                             Cl  OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOCH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOCH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOCH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOCH.sub.3                                                                             Cl  OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-CO.sub. 2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H CO.sub.2 CH.sub.2 CH.sub.3                                                               Cl  OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub. 3).sub.2                                                                   CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-CO.sub.2 CH.sub.2 CH.sub.3                                                              H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           H  4-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                           H  4-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H  4-C(O)N(CH.sub. 3).sub.2                                                                  H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           H  4-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            H  4-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            H  4-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                    Cl  OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub. 3                                                                         4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub. 2 CH.sub.3                                                         H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             Br                                                                               Br        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H S(O).sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H S(O).sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H S(O).sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 N(CH.sub.3).sub.2                                                            H S(O).sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H S(O).sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H S(O).sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H S(O).sub.2 N(CH.sub.3).sub.2                                                             CH.sub.2                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H S(O).sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H S(O).sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H S(O).sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H S(O).sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H S(O).sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H S(O).sub.2 N(CH.sub.3).sub.3                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H S(O).sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H S(O).sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H S(O).sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-C(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-C(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-C(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-C(O).sub.2 N(CH.sub.3).sub.2                                                            H CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H C(O)N(CH.sub.3 ).sub.2                                                                   CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub. 3                                                                              H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.3 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H S(O).sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O)CH.sub.3                                                                            H S(O).sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-S(O).sub.2 CH.sub.3                                                                     H S(O).sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CHO       CH.sub. 3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.3                                                                               H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.3                                                                               H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.3                                                                      H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub. 2 CH.sub.2 CH.sub.3                                                            H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                            CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                           CH.sub.3                                                                          4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHNOH     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                           __________________________________________________________________________

                                      TABLE IIIb                                   __________________________________________________________________________     General Formula IIIb                                                           R  R.sub.1    R.sub.x                                                                          Q.sub.2                                                                               X   Y   Z  m.p. (°C.)                            __________________________________________________________________________     H  2-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  2-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub. 3                                                                         CH                                              H  2-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  2-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  2-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O)CH.sub.2 CH.sub.3                                                                   H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH.sub.2 CH.sub.3                                                            H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub. 3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH(CH.sub.3).sub.2                                                                     H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     CH.sub. 3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O)CH(CH.sub.3).sub.2                                                                  H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-S(O).sub.2 CH(CH.sub.3).sub.2                                                           H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-SO.sub. 2 N(CH.sub.3).sub.2                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub. 3                                                           CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CHO    CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.3                                                                               H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H CHO    Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CHO    CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H CHO    Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    Cl  OCH.sub.3                                                                          CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H CHO    CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-CO.sub.2 CH.sub.3                                                                       H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-CO.sub.2 CH.sub.3                                                                       H CHO    Cl  OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H CHO    CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-C(O)N(CH.sub.3).sub.2                                                                   H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-C(O)N(CH.sub.3).sub.2                                                                   H CHO    Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 CH  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 Cl  OCH.sub.3                                                                          CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub. 3                                                                         CH                                              H  2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 Cl  OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  2-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  2-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  2-C(O)N(CH.sub.3).sub.2                                                                   H C(O)N(CH.sub.3).sub.2                                                                 Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H SCH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.3                                                                               H SCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H SCH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H SCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H SCH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H SCH.sub.3                                                                             Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H SCH.sub.2 CH.sub.3                                                                    Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                           CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                           CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                           CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H SCH.sub.2 CH.sub.2 CH.sub.3                                                           Cl  OCH.sub. 3                                                                         CH                                              H  5-SCH.sub.3                                                                               H CH═NOH                                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.3                                                                               H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.3                                                                               H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.3                                                                               H CH═NOH                                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            CH.sub. 3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            Cl  OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H  5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H  5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H  5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               H  5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            Cl  OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-S(O)CH.sub.3                                                                            H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub. 3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-S(O).sub.2 CH.sub.3                                                                     H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-SO.sub.2 N(CH.sub.3).sub.2                                                              H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub. 3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-C(O)N(CH.sub.3).sub.2                                                                   H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.3                                                                               H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.3                                                                               H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.3                                                                               H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.3                                                                               H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H CHO    OCH.sub. 3                                                                         OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H CHO    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H CHO    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.3                                                                               H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 CH.sub. 3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          2-CO.sub.2 CH.sub.3                                                                       H C(O)N(CH.sub.3).sub.2                                                                 OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.3                                                                               H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.3                                                                               H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.3                                                                               H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.3                                                                               H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.3                                                                      H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═ NOH                                                                           CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               CH.sub.3                                                                          5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              CH.sub.3                                                                          5-CO.sub.2 CH.sub.3                                                                       H CH═NOH                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              __________________________________________________________________________

                  TABLE IVb                                                        ______________________________________                                         General Formula IVb                                                                                                      m.p.                                 RR.sub.1      R.sub.x                                                                              Q.sub.2  X       Y    (°C.)                         ______________________________________                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               O                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              O                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     O                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            O                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.2                                  H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.2                                  H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.2                                  H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            CH.sub.2                                  H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               O                                         H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              O                                         H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     O                                         H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCF.sub. 2 H                                                                           O                                         H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.2                                  H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.2                                  H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.2                                  H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            CH.sub.2                                  H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               O                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              O                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     O                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            O                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.2                                  H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.2                                  H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.2                                  H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCF.sub. 2 H                                                                           CH.sub.2                                  H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               O                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              O                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     O                                         H 4-S(O)CH.sub.2 CH.sub.3 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            O                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.2                                  H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.2                                  H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.2                                  H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            CH.sub.2                                  H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               O                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              O                                         H 4-S(O).sub.2 Ch.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     O                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            O                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.2                                  H 4-S(O).sub.2 CH.sub.2 CH.sub.2 Ch.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.2                                  H 4-S(O).sub.2 CH.sub.2 Ch.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.2                                  H 4-S(O).sub.2 CH.sub.2 Ch.sub.2 CH.sub.3                                                    H     CO.sub.2 Ch.sub.3                                                                       OCF.sub.2 H                                                                            CH.sub.2                                  ______________________________________                                    

                  TABLE Vb                                                         ______________________________________                                         General Formula Vb                                                                                                       m.p.                                 R   R.sub.1         R.sub.x                                                                              Q.sub.2                                                                               X.sub.1  (°C.)                         ______________________________________                                         H   4-SCH.sub.3     H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                      H   4-SCH.sub.3     H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                     H   4-SCH.sub.3     H     CO.sub.2 CH.sub.3                                                                     OCF.sub.2 CH.sub.3                            H   4-SCH.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                      H   4-SCH.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                     H   4-SCH.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.3                                                                     OCF.sub.2 CH.sub.3                            H   4-S(O)CH.sub.2 CH.sub.3                                                                        H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                      H   4-S(O)CH.sub.2 CH.sub.3                                                                        H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                     H   4-S(O)CH.sub.2 CH.sub.3                                                                        H     CO.sub.2 CH.sub.3                                                                     OCF.sub.2 CH.sub.3                            H   4-S(O).sub.2 CH.sub.2 CH.sub.3                                                                 H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                      H   4-S(O).sub.2 CH.sub.2 CH.sub.3                                                                 H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                     H   4-S(O).sub.2 CH.sub.2 CH.sub.3                                                                 H     CO.sub.2 CH.sub.3                                                                     OCF.sub. 2 CH.sub.3                           H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                  H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                      H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                  H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                     H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                  H     CO.sub.2 CH.sub.3                                                                     OCF.sub.2 CH.sub.3                            H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                               H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                      H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                               H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                     H   4-S(O)CH.sub.2 CH.sub.3 CH.sub.3                                                               H     CO.sub.2 CH.sub.3                                                                     OCF.sub.2 CH.sub.3                            H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                      H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                     H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        H     CO.sub.2 CH.sub.3                                                                     OCF.sub.2 CH.sub.3                            ______________________________________                                    

                  TABLE VIb                                                        ______________________________________                                         General Formula VIb                                                                                                  m.p.                                     RR.sub.1      R.sub.x                                                                              Q.sub.2           (°C.)                             ______________________________________                                                                      X.sub.1 Y.sub.2                                   H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               H                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              H                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     H                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            H                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                  H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.3                                  H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.3                                  H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            CH.sub.3                                  H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               H                                         H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              H                                         H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub. 2 CH.sub.3                                                                    H                                         H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub. 2 CH.sub.3                                                                      OCF.sub.2 H                                                                            H                                         H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                  H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.3                                  H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.3                                  H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            CH.sub.3                                  H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               H                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              H                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     H                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            H                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                  H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.3                                  H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.3                                  H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub. 2 CH.sub.3                                                                      OCF.sub.2 H                                                                            CH.sub.3                                  H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               H                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              H                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     H                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            H                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                  H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.3                                  H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.3                                                               X       Y                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            CH.sub.3                                  H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               H                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              H                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     H                                         H 4-S(O).sub.2 Ch.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            H                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                               CH.sub.3                                  H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                              CH.sub.3                                  H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.2 CH.sub.3                                                                     CH.sub.3                                  H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCF.sub.2 H                                                                            CH.sub.3                                  ______________________________________                                    

                  TABLE VIIb                                                       ______________________________________                                         General Formula VIIb                                                                                                     m.p.                                 RR.sub.1      R.sub.x                                                                              Q.sub.2  X.sub.1                                                                              Y.sub.3                                                                               (°C.)                         ______________________________________                                         H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                    H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.3                                    H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.3                                    H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CH.sub.3                           H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CH.sub.3                           H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CF.sub.3                           H 4-SCH.sub.3 H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                    H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.3                                    H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.3                                    H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CH.sub.3                           H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CH.sub.3                           H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CF.sub.3                           H 4-SCH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                    H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.3                                    H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.3                                    H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CH.sub.3                           H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CH.sub.3                           H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-SCH.sub.2 CH.sub.2 CH.sub. 3                                                             H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CF.sub.3                           H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                    H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.3                                    H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.3                                    H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CH.sub.3                           H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CH.sub.3                           H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CF.sub.3                           H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                    H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.3                                    H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.3                                    H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CH.sub.3                           H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CH.sub.3                           H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       SCH.sub.3                                                                            CH.sub.2 CF.sub.3                           H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.2 CF.sub.3                           H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            CH.sub.2 CF.sub.3                           ______________________________________                                    

                  TABLE VIIIb                                                      ______________________________________                                         General Formula VIIIb                                                                                                    m.p.                                 R   R.sub.1         R.sub.x                                                                              Q.sub.2  X.sub.3                                                                               (°C.)                         ______________________________________                                         H   4-SCH.sub.3     H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                    H   4-SCH.sub.3     H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                   H   4-SCH.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                    H   4-SCH.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                   H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                  H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                    H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                  H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                   H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                               H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                    H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                               H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                   H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        H     CO.sub.2 CH.sub.3                                                                       CH.sub.3                                    H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        H     CO.sub.2 CH.sub.3                                                                       OCH.sub.3                                   H   4-SCH.sub.3     H     CO.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                    H   4-SCH.sub.3     H     CO.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                   H   4-SCH.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                    H   4-SCH.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                   H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                  H     CO.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                    H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                  H     CO.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                   H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                               H     CO.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                    H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                               H     CO.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                   H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        H     CO.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                    H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        H     CO.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                   ______________________________________                                    

                                      TABLE IXb                                    __________________________________________________________________________     General Formula IXb                                                            R R.sub.1    R.sub.x                                                                           Q.sub.2                                                                             X   Y    Z  m.p. (°C.)                             __________________________________________________________________________     H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           CH.sub.3                                                                            CH                                               H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                   OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                               H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                   Cl  OCH.sub.3                                                                           CH                                               H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           OCH.sub.3                                                                           N                                                H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           CH.sub.3                                                                            CH                                               H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                   OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                               H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                   Cl  OCH.sub.3                                                                           CH                                               H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           OCH.sub.3                                                                           N                                                H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           CH.sub.3                                                                            CH                                               H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                   OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                               H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                   Cl  OCH.sub.3                                                                           CH                                               H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           OCH.sub.3                                                                           N                                                H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           CH.sub.3                                                                            CH                                               H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                   OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                               H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                   Cl  OCH.sub.3                                                                           CH                                               H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           OCH.sub.3                                                                           N                                                H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           CH.sub.3                                                                            CH                                               H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                   OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                               H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                   Cl  OCH.sub.3                                                                           CH                                               H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           OCH.sub.3                                                                           N                                                __________________________________________________________________________

                                      TABLE Xb                                     __________________________________________________________________________     General Formula Xb                                                             R R.sub.1    R.sub.x                                                                          Q.sub.2 X   Y   Z  m.p. (°C.)                            __________________________________________________________________________     H 4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H 4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H 4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                      Cl  OCH.sub.3                                                                          CH                                              H 4-SCH.sub.3                                                                               H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H 4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H 4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H 4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                      Cl  OCH.sub.3                                                                          CH                                              H 4-SCH.sub.2 CH.sub.3                                                                      H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                      Cl  OCH.sub.3                                                                          CH                                              H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                      Cl  OCH.sub.3                                                                          CH                                              H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                      Cl  OCH.sub.3                                                                          CH                                              H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.3                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.3                                                                              Cl  OCH.sub.3                                                                          CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.3                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.2 CH.sub.3                                                                     Cl  OCH.sub.3                                                                          CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           OCH.sub.3                                                                          N                                               H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.2 CH.sub.2 CH.sub.3                                                            Cl  OCH.sub.3                                                                          CH                                              H 4-CO.sub.2 CH.sub.3                                                                       H SCH.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                               __________________________________________________________________________

                                      TABLE XIb                                    __________________________________________________________________________     General Formula XIb                                                            R R.sub.1    R.sub.x                                                                           Q.sub.2 X     Y   m.p.(°C.)                             __________________________________________________________________________     H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             O                                                H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            O                                                H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   O                                                H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          O                                                H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.2                                         H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.2                                         H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                         H 4-SCH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.2                                         H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             O                                                H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            O                                                H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   O                                                H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          O                                                H 4-SCH.sub. 2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.2                                         H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.2                                         H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                         H 4-SCH.sub.2 CH.sub.3                                                                      H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.2                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             O                                                H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            O                                                H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   O                                                H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          O                                                H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.2                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.2                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                         H 4-SCH.sub.2 CH.sub.2 CH.sub.3                                                             H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.2                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             O                                                H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            O                                                H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   O                                                H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          O                                                H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.2                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.2                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                         H 4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                          H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.2                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             O                                                H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            O                                                H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   O                                                H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          O                                                H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.2                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.2                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                         H 4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                   H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.3                                                                              CH.sub.3                                                                             O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.3                                                                              OCH.sub.3                                                                            O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.3                                                                              OCH.sub.2 CH.sub.3                                                                   O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.3                                                                              OCF.sub.2 H                                                                          O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.3                                                                              CH.sub.3                                                                             CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.3                                                                              OCH.sub.3                                                                            CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.3                                                                              OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.3                                                                              OCF.sub.2 H                                                                          CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.3                                                                     OCH.sub.2 CH.sub.3                                                                   O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.3                                                                     OCF.sub.2 H                                                                          O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.3                                                                     OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            OCF.sub.2 H                                                                          CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                             O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                            O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.2 CH.sub.3                                                                   O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            OCF.sub.2 H                                                                          O                                                H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            CH.sub.3                                                                             CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                            CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                         H 4-CO.sub.2 CH.sub.3                                                                       H  SCH.sub.2 CH.sub.2 CH.sub.3                                                            OCF.sub.2 H                                                                          CH.sub.2                                         __________________________________________________________________________

                  TABLE XIIb                                                       ______________________________________                                         General Formula XIIb                                                                                                     m.p.                                 R   R.sub.1        R.sub.x                                                                              Q.sub.2   X.sub.1                                                                               (°C.)                         ______________________________________                                         H   4-SCH.sub.3    H     CO.sub.2 CH.sub.3                                                                        CH.sub.3                                    H   4-SCH.sub.3    H     CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                   H   4-SCH.sub.3    H     CO.sub.2 CH.sub.3                                                                        OCF.sub.2 CH.sub.3                          H   4-SCH.sub.2 CH.sub.3                                                                          H     CO.sub.2 CH.sub.3                                                                        CH.sub.3                                    H   4-SCH.sub.2 CH.sub.3                                                                          H     CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                   H   4-SCH.sub.2 CH.sub.3                                                                          H     CO.sub.2 CH.sub.3                                                                        OCF.sub.2 CH.sub.3                          H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                 H     CO.sub.2 CH.sub.3                                                                        CH.sub.3                                    H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                 H     CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                   H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                 H     CO.sub.2 CH.sub.3                                                                        OCF.sub.2 CH.sub.3                          H   4-S(O)CH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                        CH.sub.3                                    H   4-S(O)CH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                   H   4-S(O)CH.sub.2 CH.sub.3                                                                       H     CO.sub.2 CH.sub.3                                                                        OCF.sub.2 CH.sub.3                          H   4-S(O).sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                        CH.sub.3                                    H   4-S(O).sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                   H   4-S(O).sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                        OCF.sub.2 CH.sub.3                          H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                        CH.sub.3                                    H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                   H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                        OCF.sub.2 CH.sub.3                          H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H     CO.sub.2 CH.sub.3                                                                        CH.sub.3                                    H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H     CO.sub.2 CH.sub.3                                                                        OCH.sub.3                                   H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H     CO.sub.2 CH.sub.3                                                                        OCF.sub.2 CH.sub.3                          H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.3 CH.sub.3                                    H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.3 OCH.sub.3                                   H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.3 OCF.sub.2 CH.sub.3                          H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.3                                                                       CH.sub.3                                    H   4-CO.sub.2 CH.sub. 3                                                                          H     SCH.sub.2 CH.sub.3                                                                       OCH.sub.3                                   H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.3                                                                       OCF.sub.2 CH.sub.3                          H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                    H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                   H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.2 CH.sub.3                                                              OCF.sub.2 CH.sub.3                          H   4-SO.sub.2 N(CH.sub.3).sub.2                                                                  5-Br  Br        CH.sub.3                                    H   4-SO.sub.2 N(CH.sub.3).sub.2                                                                  5-Br  Br        OCH.sub.3                                   H   4-SO.sub.2 N(CH.sub.3).sub.2                                                                  5-Br  Br        OCF.sub.2 CH.sub.3                          ______________________________________                                    

                                      TABLE XIIIb                                  __________________________________________________________________________     General Formula XIIIb                                                          R  R.sub.1   R.sub.x                                                                           Q.sub.2 X.sub.1                                                                              Y.sub.2                                                                            m.p.(°C.)                             __________________________________________________________________________     H  4-SCH.sub.3                                                                              H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             H                                                H  4-SCH.sub.3                                                                              H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            H                                                H  4-SCH.sub.3                                                                              H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   H                                                H  4-SCH.sub.3                                                                              H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          H                                                H  4-SCH.sub.3                                                                              H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                         H  4-SCH.sub.3                                                                              H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                         H  4-SCH.sub.3                                                                              H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.3                                         H  4-SCH.sub.3                                                                              H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.3                                         H  4-SCH.sub.2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             H                                                H  4-SCH.sub.2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            H                                                H  4-SCH.sub.2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   H                                                H  4-SCH.sub.2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          H                                                H  4-SCH.sub.2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                         H  4-SCH.sub.2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                         H  4-SCH.sub.2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.3                                         H  4-SCH.sub.2 CH.sub.3                                                                     H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.3                                         H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                            H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             H                                                H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                            H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            H                                                H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                            H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   H                                                H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                            H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          H                                                H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                            H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                         H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                            H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                         H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                            H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.3                                         H  4-SCH.sub.2 CH.sub.2 CH.sub.3                                                            H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.3                                         H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                         H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             H                                                H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                         H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            H                                                H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                         H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   H                                                H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                         H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          H                                                H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                         H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                         H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                         H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                         H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                         H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.3                                         H  4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                         H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.3                                         H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             H                                                H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            H                                                H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   H                                                H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          H                                                H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H  CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                         H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H  CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                         H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H  CO.sub.2 CH.sub.3                                                                      OCH.sub.2 CH.sub.3                                                                   CH.sub.3                                         H  4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                  H  CO.sub.2 CH.sub.3                                                                      OCF.sub.2 H                                                                          CH.sub.3                                         __________________________________________________________________________

                  TABLE XIVb                                                       ______________________________________                                         General Formula XIVb                                                                                                       m.p.                               R   R.sub.1       R.sub.x                                                                              Q.sub.2                                                                               X.sub.2                                                                              Y.sub.3                                                                               (°C.)                       ______________________________________                                         H   4-SCH.sub.3   H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                  H   4-SCH.sub.3   H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                  H   4-SCH.sub.3   H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.3                                  H   4-SCH.sub.3   H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CH.sub.3                         H   4-SCH.sub.3   H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CH.sub.3                         H   4-SCH.sub.3   H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-SCH.sub.3   H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CF.sub.3                         H   4-SCH.sub.3   H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-SCH.sub.2 CH.sub.3                                                                         H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                  H   4-SCH.sub.2 CH.sub.3                                                                         H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                  H   4-SCH.sub.2 CH.sub.3                                                                         H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.3                                  H   4-SCH.sub.2 CH.sub.3                                                                         H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CH.sub.3                         H   4-SCH.sub.2 CH.sub.3                                                                         H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CH.sub.3                         H   4-SCH.sub.2 CH.sub.3                                                                         H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-SCH.sub.2 CH.sub.3                                                                         H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CF.sub.3                         H   4-SCH.sub.2 CH.sub.3                                                                         H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                  H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                  H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.3                                  H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CH.sub.3                         H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CH.sub.3                         H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-SCH.sub.2 CH.sub.2 CH.sub. 3                                                               H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CF.sub.3                         H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                  H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                  H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.3                                  H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CH.sub.3                         H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CH.sub.3                         H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CF.sub.3                         H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                  H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                  H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.3                                  H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CH.sub.3                         H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CH.sub.3                         H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H     CO.sub.2 CH.sub.3                                                                     SCH.sub.3                                                                            CH.sub.2 CF.sub.3                         H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H     CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.2 CF.sub.3                         H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H     CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.2 CF.sub.3                         ______________________________________                                    

                  TABLE XVb                                                        ______________________________________                                         General Formula XVb                                                                                                      m.p.                                 R   R.sub.1        R.sub.x                                                                              Q.sub.2     X.sub.3                                                                             (°C.)                         ______________________________________                                         H   4-SCH.sub.3    H     CO.sub.2 CH.sub.3                                                                          CH.sub.3                                  H   4-SCH.sub.3    H     CO.sub.2 CH.sub.3                                                                          OCH.sub.3                                 H   4-SCH.sub.2 CH.sub.3                                                                          H     CO.sub.2 CH.sub.3                                                                          CH.sub.3                                  H   4-SCH.sub.2 CH.sub.3                                                                          H     CO.sub.2 CH.sub.3                                                                          OCH.sub.3                                 H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                 H     CO.sub.2 CH.sub.3                                                                          CH.sub.3                                  H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                 H     CO.sub.2 CH.sub.3                                                                          OCH.sub.3                                 H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                          CH.sub.3                                  H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              H     CO.sub.2 CH.sub.3                                                                          OCH.sub.3                                 H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H     CO.sub.2 CH.sub.3                                                                          CH.sub.3                                  H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H     CO.sub.2 CH.sub.3                                                                          OCH.sub.3                                 H   4-CO.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.3                                                                          CH.sub.3                                  H   4-CO.sub.2 CH.sub.3                                                                           H     CO.sub.2 CH.sub.3                                                                          OCH.sub.3                                 H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.3   CH.sub.3                                  H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.3   OCH.sub.3                                 H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.3                                                                         CH.sub.3                                  H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.3                                                                         OCH.sub.3                                 H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                  H   4-CO.sub.2 CH.sub.3                                                                           H     SCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                 H   4-CO.sub.2 CH.sub.3                                                                           H     S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             CH.sub.3                                  H   4-CO.sub.2 CH.sub.3                                                                           H     S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                             OCH.sub.3                                 H   4-CO.sub.2 CH.sub.3                                                                           H     S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      CH.sub.3                                  H   4-CO.sub.2 CH.sub.3                                                                           H     S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      OCH.sub.3                                 H   4-CO.sub.2 CH.sub.3                                                                           H     CHO         CH.sub.3                                  H   4-CO.sub.2 CH.sub.3                                                                           H     CHO         OCH.sub.3                                 H   4-SCH.sub.3    H     CHO         CH.sub.3                                  H   4-SCH.sub.3    H     CHO         OCH.sub.3                                 H   4-SCH.sub.2 CH.sub.3                                                                          H     CHO         CH.sub.3                                  H   4-SCH.sub.2 CH.sub.3                                                                          H     CHO         OCH.sub.3                                 H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                 H     CHO         CH.sub.3                                  H   4-SCH.sub.2 CH.sub.2 CH.sub.3                                                                 H     CHO         OCH.sub.3                                 H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              H     CHO         CH.sub.3                                  H   4-S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              H     CHO         OCH.sub.3                                 H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H     CHO         CH.sub.3                                  H   4-S(O).sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H     CHO         OCH.sub.3                                 ______________________________________                                    

Formulations

Useful formulations of the compounds of Formula I can be prepared in conventional ways. They include dusts, granules, pellets, solutions, suspensions, emulsions, wettable powders, emulsifiable concentrates and the like. Many of these may be applied directly. Sprayable formulations ca be extended in suitable media and used at spray volumes of from a few liters to several hundred liters per hectare. High strength compositions are primarily used as intermediates for further formulation. The formulations, broadly, contain about 0.1% to 99% by weight of active ingredient (s) and at least one of (a) about 0.1% to 20% surfactant(s) and (b) about 1% to 99.9% solid or liquid inert diluent(s). More specifically, they will contain these ingredients in the following approximate proportions:

    ______________________________________                                                     Active  Weight Percent*                                                        Ingredient                                                                             Diluent(s)                                                                               Surfactant(s)                                    ______________________________________                                         Wettable Powders                                                                             20-90      0-74     1-10                                         Oil Suspensions                                                                               3-50     40-95     0-15                                         Emulsions, Solutions,                                                          (including Emulsifiable                                                        Concentrates)                                                                  Aqueous Suspension                                                                           10-50     40-84     1-20                                         Dusts          1-25     70-99     0-5                                          Granules and Pellets                                                                         0.1-95      5-99.9  0-15                                         High Strength 90-99      0-10     0-2                                          Compositions                                                                   ______________________________________                                          *Active ingredient plus at least one of a surfactant or a diluent equals       100 weight percent.                                                      

Lower or higher levels of active ingredient can, of course, be present depending on the intended use and the physical properties of the compound. Higher ratios of surfactant to active ingredient are sometimes desirable, and are achieved by incorporation into the formulation or by tank mixing.

Typical solid diluents are described in Watkins, et al., "Handbook of Insecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books, Caldwell, N.J., but other solids, either mined or manufactured, may be used. The more absorptive diluents are preferred for wettable powders and the denser ones for dusts. Typical liquid diluents and solvents are described in Marsden, "Solvents Guide," 2nd Ed., Interscience, New York, 1950. Solubility under 0.1% is preferred for suspension concentrates; solution concentrates are preferably stable against phase separation at 0° C. "McCutcheon's Detergents and Emulsifiers Annual", MC Publishing Corp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia of Surface Active Agents", Chemical Publishing Co., Inc., New York, 1964, list surfactants and recommended uses. All formulations can contain minor amounts of additives to reduce foaming, caking, corrosion, microbio-logical growth, etc.

The methods of making such compositions are well known. Solutions are prepared by simply mixing the ingredients. Fine solid compositions are made by blending and, usually, grinding as in a hammer or fluid energy mill. Suspensions are prepared by wet milling (see, for example, Littler, U.S. Pat. No. 3,060,084). Granules and pellets may be made by spraying the active material upon preformed granular carriers or by agglomeration techniques. See J. E. Browning, "Agglomeration", Chemical Engineering, Dec. 4, 1967, pp. 147ff. and "Perry's Chemical Engineer's Handbook", 5th Ed., McGraw-Hill, New York, 1973, pp. 8-57ff.

For further information regarding the art of formulation, see for example:

H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16 through Col. 7, line 19 and Examples 10 through 41;

R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line 43 through Col.7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58, 132, 138-140, 162-164, 166, 167 and 169-182;

H. Gysin and E. Knusli, U.S. Pat. No. 2,891,855, June 23, 1959, Col. 3, line 66 through Col. 5, line 17 and Examples 1-4;

G. C. Klingman, "Weed Control as a Science", John Wiley and Sons, Inc., New York, 1961, pp. 81-96; and

J. D. Fryer and S. A. Evans, "Weed Control Handbook", 5th Ed., Blackwell Scientific Publications, Oxford, 1968, pp. 101-103.

In the following examples, all parts are by weight unless otherwise indicated.

EXAMPLE 19 Wettable Powder

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-[2-(dimethylaminosulfonyl)ethyl]-3-thiophenesulfonamide: 80%

sodium alkylnaphthalenesulfonate: 2%

sodium ligninsulfonate: 2%

synthetic amorphous silica: 3%

kaolinite: 13%

The ingredients are blended, hammer-milled until all the solids are essentially under 50 microns, reblended, and packaged.

EXAMPLE 20 Wettable Powder

2-[2-(dimethylaminosulfonyl)ethyl]-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophenesulfonamide: 50%

sodium alkylnaphthalenesulfonate: 2%

low viscosity methyl cellulose: 2%

diatomaceous earth: 46%

The ingredients are blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in diameter. The product is reblended before packaging.

EXAMPLE 21 Granule

Wettable Powder of Example 20: 5%

attapulgite granules (U.S.S. 20-40 mesh; 0.84-0.42 mm): 95%

A slurry of wettable powder containing 25% solids is sprayed on the surface of attapulgite granules in a double-cone blender. The granules are dried and packaged.

EXAMPLE 22 Extruded Pellet

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide: 25%

anhydrous sodium sulfate: 10%

crude calcium ligninsulfonate: 5%

sodium alkylnaphthalenesulfonate: 1%

calcium/magnesium bentonite: 59%

The ingredients are blended, hammer-milled and then moistened with about 12% water. The mixture is extruded as cylinders about 3 mm diameter which are cut to produce pellets about 3 mm long. These may be used directly after drying, or the dried pellets may be crushed to pass a U.S.S. No. 20 sieve (0.84 mm openings). The granules held on a U.S.S. No. 40 sieve (0.42 mm openings) may be packaged for use and the fines recycled.

EXAMPLE 23 Low Strength Granule

N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide: 0.1%

attapulgite granules (U.S.S. 20-40 mesh): 99.9%

The active ingredient is dissolved in a solvent and the solution is sprayed upon dedusted granules in a double-cone blender. After spraying of the solution has been completed, the material is warmed to evaporate the solvent. The material is allowed to cool and then packaged.

EXAMPLE 24 Granule

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-[2-(dimethylaminosulfonyl)ethyl]-3-thiophenesulfonamide: 80%

wetting agent: 1%

crude ligninsulfonate salt (containing 5-20% of the natural sugars): 10%

attapulgite clay: 9%

The ingredients are blended and milled to pass through a 100 mesh screen. This material is then added to a fluid bed granulator, the air flow is adjusted to gently fluidize the material, and a fine spray of water is sprayed onto the fluidized material. The fluidization and spraying are continued until granules of the desired size range are made. The spraying is stopped, but fluidization is continued, optionally with heat, until the water content is reduced to the desired level, generally less than 1%. The material is then discharged, screened to the desired size range, generally 14-100 mesh (1410-149 microns), and packaged for use.

EXAMPLE 25 Low strength Granule

2-[2-(dimethylaminosulfonyl)ethyl]-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophenesulfonamide: 1%

N,N-dimethylformamide: 9%

attapulgite granules (U.S.S. 20-40 sieve): 90%

The active ingredient is dissolved in the solvent and the solution is sprayed upon dedusted granules in a double cone blender. After spraying of the solution has been completed, the blender is allowed to run for a short period and then the granules are packaged.

EXAMPLE 26 Aqueous Suspension

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide: 40.0%

polyacrylic acid thickener: 0.3%

dodecylphenol polyethylene glycol ether: 0.5%

disodium phosphate: 1.0%

monosodium phosphate: 0.5%

polyvinyl alcohol: 1.0%

water: 56.7%

The ingredients are blended and ground together in a sand mill to produce particles essentially all under 5 microns in size.

EXAMPLE 27 Solution

N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide, sodium salt: 5%

water: 95%

The salt is added directly to the water with stirring to produce the solution, which may then be packaged for use.

EXAMPLE 28 High Strength Concentrate

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-[2-(dimethylaminosulfonyl)ethyl]-3-thiophenesulfonamide: 99.0%

silica aerogel: 0.5%

synthetic amorphous silica: 0.5%

The ingredients are blended and ground in a hammer-mill to produce a material essentially all passing a U.S.S. No. 50 screen (0.3 mm opening). The concentrate may be formulated further if necessary.

EXAMPLE 29 Wettable Powder

2-[2-(dimethylaminosulfonyl)ethyl]-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophenesulfonamide: 90.0%

dioctyl sodium sulfosuccinate: 0.1%

synthetic fine silica: 9.9%

The ingredients are blended and ground in a hammer-mill to produce particles essentially all below 100 microns. The material is sifted through a U.S.S. No. 50 screen and then packaged.

EXAMPLE 30 Wettable Powder

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide: 40%

sodium ligninsulfonate: 20%

montmorillonite clay: 40%

The ingredients are thoroughly blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in size. The material is reblended and then packaged.

EXAMPLE 31 Oil Suspension

N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide: 35%

blend of polyalcohol carboxylic esters and oil soluble petroleum sulfonates: 6%

xylene: 59%

The ingredients are combined and ground together in a sand mill to produce particles essentially all below 5 microns. The product can be used directly, extended with oils, or emulsified in water.

EXAMPLE 32 Dust

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-[2-(dimethylaminosulfonyl)ethyl]-3-thiophenesulfonamide: 10%

attapulgite: 10%

Pyrophyllite: 80%

The active ingredient is blended with attapulgite and then passed through a hammer-mill to produce particles substantially all below 200 microns. The ground concentrate is then blended with powdered pyrophyllite until homogeneous.

EXAMPLE 33 Oil Suspension

2-[2-(dimethylaminosulfonyl)ethyl]-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophenesulfonamide: 25%

polyoxyethylene sorbitol hexoleate: 5%

highly aliphatic hydrocarbon oil: 70%

The ingredients are ground together in a sand mill until the solid particles have been reduced to under about 5 microns. The resulting thick suspension may be applied directly, but preferably after being extended with oils or emulsified in water.

EXAMPLE 34 Wettable Powder

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide: 20%

sodium alkylnaphthalenesulfonate: 4%

sodium ligninsulfonate: 4%

low viscosity methyl cellulose: 3%

attapulgite: 69%

The ingredients are thoroughly blended. After grinding in a hammer-mill to produce particles essentially all below 100 microns, the material is reblended and sifted through a U.S. S. No. 50 sieve (0.3 mm opening) and packaged.

Utility

The compounds of the present invention are expected to be highly active preemergent or postemergent herbicides or plant growth regulants. Many of them should have utility for broad-spectrum pre- and/or post-emergence weed controlin areas where complete control of all vegetation is desired, such as around fuel storage tanks, ammunition depots, industrial storage areas, parking lots, drive-in theaters, around billboards, highway and railroad structures. Some of the compounds have utility for selective weed control in crops, such as soybean, corn, wheat, barley and cotton. Alternatively, the subject compounds should be useful to modify plant growth.

The rates of application for the compounds of the invention are determined by a number of factors, including their use as plant growth modifiers or as herbicides, the crop species involved, the types of weeds to be controlled, weather and climate, formulations selected, mode of application, amount of foliage present, etc. In general terms, the subject compounds should be applied at levels of around 0.001 to 20 kg/ha, the lower rates being suggested for use on lighter soils and/or those having a low organic matter content, for plant growth modification or for situations where only short-term persistence is required. Those compounds which exhibited no activity at test rates indicated in the biological tables are expected to show activity at higher application rates.

The compounds of the invention may be used in combination with any other commercial herbicide, examples of which are those of the triazine, triazole, uracil, urea, amide, diphenylether, carbamate and bipyridylium types.

Test A

Seeds of crabgrass (Digitaria spp.), barnyardgrass (Echinochloa crusgalli), wild oats (Avena fatua), morningglory (Ipomea spp.), cocklebur (Xanthium pensylvanicum), velvetleaf(Abutilon theophrasti), giant foxtail (Setaria faberii), cheatgrass (Bromus secalinus L.), sorghum, corn, soybean, sugarbeet, cotton, rice, barley, wheat and purple nutsedge (Cyperus rotundus) tubers were planted and treated preemergence with the test chemicals dissolved in a nonphytotoxic solvent. At the same time, these crop and weed species were treated with a soil/foliage application. At the time of treatment, the plants ranged in height from 2 to 18 cm. Treated plants and controls were maintained in a greenhouse for sixteen days, after which all species were compared to controls and visually rated for response to treatment. The ratings, summarized in Table A, are based on a numerical scale extending from 0=no injury, to 10=complete kill. The accompanying descriptive symbols have the following meanings:

C=chlorosis/necrosis;

B=burn;

D=defoliation;

E=emergence inhibition;

G=growth retardation;

H=formative effect;

U=unusual pigmentation;

X=axillary stimulation;

S=albinism; and

6Y=abscised buds or flowers.

    ______________________________________                                         Compounds                                                                      ______________________________________                                          ##STR127##                                                                    Compound   Q        X         Y       Z                                        ______________________________________                                          1         CN       CH.sub.3  CH.sub.3                                                                               CH                                        2         CN       CH.sub.3  OCH.sub.3                                                                              CH                                        3         CN       CH.sub.3  OCH.sub.3                                                                              N                                         4         CN       OCH.sub.3 OCH.sub.3                                                                              N                                         5         CN       Cl        OCH.sub.3                                                                              CH                                       ______________________________________                                          ##STR128##                                                                    Compound                                                                               Q            R      X      Y     Z                                     ______________________________________                                          6      CN           H      CH.sub.3                                                                              CH.sub.3                                                                             CH                                     7      CN           H      OCH.sub.3                                                                             CH.sub.3                                                                             CH                                     8      CN           H      OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                     9      CN           H      Cl     OCH.sub.3                                                                            CH                                    10      CN           H      OCH.sub.3                                                                             CH.sub.3                                                                             N                                     11      CN           H      OCH.sub.3                                                                             OCH.sub.3                                                                            N                                     12      CH.sub.2 CH.sub.2 OCH.sub.3                                                                 H      OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                    13      CH.sub.2 CH.sub.2 OCH.sub.3                                                                 H      OCH.sub.3                                                                             CH.sub.3                                                                             N                                     14      CH.sub.2 CH.sub.2 OCH.sub.3                                                                 H      CH.sub.3                                                                              CH.sub.3                                                                             CH                                    15      CH.sub.2 CH.sub.2 OCH.sub.3                                                                 H      Cl     OCH.sub.3                                                                            CH                                    16      CH.sub.2 Cl  H      CH.sub.3                                                                              CH.sub.3                                                                             CH                                    17      CH.sub.2 Cl  H      CH.sub.3                                                                              OCH.sub.3                                                                            CH                                    18      CH.sub.2 Cl  H      OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                    19      CH.sub.2 Cl  H      Cl     OCH.sub.3                                                                            CH                                    20      CH.sub.2 Cl  H      CH.sub.3                                                                              CH.sub.3                                                                             N                                     21      CH.sub.2 Cl  H      CH.sub.3                                                                              OCH.sub.3                                                                            N                                     22      CH.sub.2 Cl  H      OCH.sub.3                                                                             OCH.sub.3                                                                            N                                     23      CH.sub.2 Cl  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                                                            N                                     ______________________________________                                          ##STR129##                                                                    Compound  Q            X        Y      Z                                       ______________________________________                                         24        CH.sub.2 Cl  CH.sub.3 CH.sub.3                                                                              CH                                      25        CH.sub.2 OCH.sub.3                                                                          CH.sub.3 CH.sub.3                                                                              CH                                      26        CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                               OCH.sub.3                                                                             CH                                      27        CH.sub.2 OCH.sub.3                                                                          Cl       OCH.sub.3                                                                             CH                                      28        CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                               CH.sub.3                                                                              N                                       29        CH.sub.2 OCH.sub.3                                                                          OCH.sub.3                                                                               OCH.sub.3                                                                             N                                       30        CH.sub.2 OCH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                               OCH.sub.3                                                                             CH                                      31        CH.sub.2 Cl  OCH.sub.3                                                                               CH.sub.3                                                                              CH                                      32        CH.sub.2 Cl  Cl       OCH.sub.3                                                                             CH                                      33        CH.sub.2 Cl  OCH.sub.3                                                                               CH.sub.3                                                                              N                                       34        CH.sub.2 Cl  OCH.sub.3                                                                               OCH.sub.3                                                                             N                                       ______________________________________                                          ##STR130##                                                                    Com-                                                                           pound Q         R.sub.1 "    X     Y     Z                                     ______________________________________                                         35    COOCH.sub.3                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    36    COOCH.sub.3                                                                              SO.sub.2 N(CH.sub.3).sub.2                                                                  CH.sub.3                                                                             OCH.sub.3                                                                            N                                     37    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                             CH.sub.3                                                                             CH                                    38    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                            CH                                    39    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    40    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.3                                                                          CH.sub.3                                                                             OCH.sub.3                                                                            N                                     41    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.3                                                                          OCH.sub.3                                                                            OCH.sub.3                                                                            N                                     42    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.3                                                                          Cl    OCH.sub.3                                                                            CH                                    43    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             CH.sub.3                                                                             CH                                    44    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                            CH                                    45    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    46    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                             OCH.sub.3                                                                            N                                     47    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                            OCH.sub.3                                                                            N                                     48    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.3                                                                       Cl    OCH.sub.3                                                                            CH                                    49    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH.sub.3                                                                             CH                                    50    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                            CH                                    51    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    52    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             OCH.sub.3                                                                            N                                     53    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.3                                                                  OCH.sub.3                                                                            OCH.sub.3                                                                            N                                     54    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.3                                                                  Cl    OCH.sub.3                                                                            CH                                    55    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             CH.sub.3                                                                             CH                                    56    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                            CH                                    57    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    58    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                 CH.sub.3                                                                             OCH.sub.3                                                                            N                                     59    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                 OCH.sub.3                                                                            OCH.sub.3                                                                            N                                     60    COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                 Cl    OCH.sub.3                                                                            CH                                    ______________________________________                                         Com-                                                                           pound Q         R            X     Y     Z                                     ______________________________________                                         61    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             CH.sub.3                                                                             CH                                    62    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                            CH                                    63    COOCH.sub.3                                                                              SO.sub.2 CH.sub. 2 CH.sub.2 CH.sub.3                                                        OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    64    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         CH.sub.3                                                                             OCH.sub.3                                                                            N                                     65    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         OCH.sub.3                                                                            OCH.sub.3                                                                            N                                     66    COOCH.sub.3                                                                              SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                         Cl    OCH.sub.3                                                                            CH                                    67    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             CH.sub.3                                                                             CH                                    68    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                    69    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    70    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                             OCH.sub.3                                                                            N                                     71    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                     72    COOCH.sub.3                                                                              S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                              Cl    OCH.sub.3                                                                            CH                                    ______________________________________                                          ##STR131##                                                                    Compound                                                                               R.sub.x                                                                               R.sub.1 "  Q.sub.2                                                                             X     Y     Z                                   ______________________________________                                         73      Br     SO.sub.2 N(CH.sub.3).sub.2                                                                Br   CH.sub.3                                                                             CH.sub.3                                                                             CH                                  74      Br     SO.sub.2 N(CH.sub.3).sub.2                                                                Br   CH.sub.3                                                                             OCH.sub.3                                                                            CH                                  75      Br     SO.sub.2 N(CH.sub.3).sub.2                                                                Br   OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                  76      Br     SO.sub.2 N(CH.sub.3).sub.2                                                                Br   CH.sub.3                                                                             OCH.sub.3                                                                            N                                   77      Br     SO.sub.2 N(CH.sub.3).sub.2                                                                Br   OCH.sub.3                                                                            OCH.sub.3                                                                            N                                   78      Br     SO.sub.2 N(CH.sub.3).sub.2                                                                Br   Cl    OCH.sub.3                                                                            CH                                  79      Br     SCH.sub.2 CH.sub.3                                                                        Br   CH.sub.3                                                                             CH.sub.3                                                                             CH                                  80      Br     SCH.sub.2 CH.sub.3                                                                        Br   CH.sub.3                                                                             OCH.sub.3                                                                            CH                                  81      Br     SCH.sub.2 CH.sub.3                                                                        Br   OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                  82      Br     SCH.sub.2 CH.sub.3                                                                        Br   CH.sub.3                                                                             OCH.sub.3                                                                            N                                   83      Br     SCH.sub.2 CH.sub.3                                                                        Br   OCH.sub.3                                                                            OCH.sub.3                                                                            N                                   84      Br     SCH.sub.2 CH.sub.3                                                                        Br   Cl    OCH.sub.3                                                                            CH                                  ______________________________________                                          ##STR132##                                                                    Compound                                                                               Q         R.sub.1 "   X     Y     Z                                    ______________________________________                                         85      COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                             OCH.sub.3                                                                            CH                                   86      COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                   87      COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                OCH.sub.3                                                                            OCH.sub.3                                                                            N                                    88      COOCH.sub.3                                                                              SCH.sub.2 CH.sub.2 CH.sub.3                                                                Cl    OCH.sub.3                                                                            CH                                   ______________________________________                                    

    TABLE A       Compound 1 Compound 2 Compound 3 Compound 4 Compound 5 Compound 6      Compound 7 Compound 8 Compound 9 Compound 10 Rate kg/ha 0.05 0.01 0.05      0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05      0.01  0.05 0.01        POSTEMERGENCE Morningglory 9C 9H 10C 9C 9C 5C,9G 4C,9H 5G 10C 10C 9C      3G 10C 9C 10C 10C 10C 5C,9G 4C,9G 2C,4G Cocklebur 10C 2C,9G 10C 9C 9C      5C,9G 0 0 10C 5G 10C 8H 10C 2C,8G 10C 10C 10C 9H 5C,9G 3C,8H Velvetleaf      10C 9C 10C 9C 9C 3C,7H 5C,9G 4G 9C 3C,8H 10C 9C 10C 10C 10C 10C 10C 10C      9C 2C,7G Nutsedge 9C 3C,9G 4C,9G 8G 5G 2G 0 0 4C,8G 5G 7G 3G 10C 7G 10C      10C 5C,9G 2C,6G 0 0 Crabgrass 8G 7G 3C,8G 2C,7G 2C,5G 0 0 0 2G 0 2G 0      2C,6G 0 3H 0 0 0 0 0 Giant Foxtail 3C,6G 1H 3C,8H 2C,6H 3C,8G 0 0 0 3G 0      2C 0 2C,6H 2G 6G 5G 2C,5G 0 0 0 Barnyardgrass 9C 2C,5H 10C 3C,8H 9C      3C,9H 3C,8H 0 4C,9H 3C,8H 3C,8H 0 3C,7H 2H 3C,8H 4G 5H 0 3G 0 Cheatgrass      6C,9G 8G 9C 2C,8G 3C,9G 2G 2G 0 2C,7G 0 5G 0 9C 5G 9C 2C,8G 4G 0 0 0      Wild Oats 9G 3C,9G 6C,9G 3C,6G 3C,7G 0 2C 0 0 0 2G 0 2C,5G 0 2G 0 0 0 0      0 Wheat 9G 2G 4C,9G 5G 3C,9G 4G 3G 0 0 0 3G 0 3C,5G 0 2G 0 0 0 0 0 Corn      10C 5U,9G 10C 4U,9C 3U,9C 9H 9H 0 5C,9G 9H 5C,9G 2C,7H 9C 3C,9H 3C,8H 5H      2C,7H 0 2C,7H 0 Barley 5C,9G 5G 3C,9H 8G 4G 0 0 0 2C 0 0 0 3C,5G 0 2G 0      0 0 0 0 Soybean 9C 9C 9C 9C 9C 5C,9G 5C,9G 4C,9G 9C 4C,8G 2C,8H 6H 4C,9G      4C,9G 5C,9G 5C,9G 5H 5G 3C,9G 2G Rice 5C,9G 4C,9G 9C 5C,9G 9C 9G 2C,9G      6G 9C 2C,7G 9C 4C,9G 9C 3C,8G 8G 6G 3C,8G 4G 3G 0 Sorghum 2U,9G 2C,8G      5C,9G 2C,8G 3C,9G 3C,8G 5G 0 4C,9H 3C,9H 9C 2C,6G 5C,9G 4C,9G 9H 8H 8H      5G 2C,3G 0 Sugar beet 9C 9C 10C 9C 9C 9C 9C 4C,5G 9C 10C 10C 10C 10C 9C      10C 10C 9C 10C 9C 10C Cotton 9C 10C 10C 10C 10C 3C,8G 4C,9H 2C,5G 9C      5C,9G 10C 4C,9G 10C 10C 10C 10C 6C,9G 4C,8G 8G 5G PREEMERGENCE Morningglo      ry 9G 9G 9G 8G 9G 7H 8H 0 9G 7G 6G 4G 9G 9G 9C 9G 8G 4G 7G 0 Cocklebur      7H 4G 3C,7H 1H 9H 0 0 0 0 -- 5G 4G 9H 8G 9H 9H 5G 8G 0 0 Velvetleaf 8G      3G 8G 7G 2G 0 0 0 3G 2G 6G 2G 10C 9G 9C 9G 7G 5G 0 0 Nutsedge 10E 10E      10E 2C,9G 0 0 0 0 9G 9G 0 0 8G 0 10E 10E 9G 0 0 0 Crabgrass 9G 3G 3C,8G      6G 0 0 0 0 0 0 0 0 5G 0 0 0 0 0 0 0 Giant Foxtail 0 0 7G 0 2G 0 0 0 0 0      0 0 5G 0 5G 0 5G 0 0 0 Barnyardgrass 8G 2G 9H 3G 7G 0 0 0 8H 4G 0 0 5G 0      6G 0 4G 0 0 0 Cheatgrass 9H 8H 4C,9H 8G 7G 0 0 0 7G 0 0 0 10E 5G 8G 7G      3G 0 0 0 Wild Oats 2C,8H 7G 4C,8H 5G 4G 0 0 0 0 0 0 0 5G 0 0 0 0 0 0 0      Wheat 9G 7G 8G 5G 8G 0 6G 0 7G 0 2G 0 0 0 0 0 0 0 0 0 Corn 9G 8G 9G 9G      9G 7H 7G 0 8G 5G 2C,8H 2C,7G 8H 3C,9H 3C,7G 2C,7G 7G 0 9H 2G Barley 9G      6G 9G 8G 3G 0 0 0 4G 0 6G 5G 9G 7G 5G 0 4G 0 0 0 Soybean 3C,9H 6H 9G      3C,7H 9H 3C,4H 3C,6H 0 2C,6G 1H 2C,7H 2C,3H 9H 9H 9G 8H 2C 0 0 0 Rice      10E 9H 10E 9H 9H 6G 9H 0 10E 9H 10E 7G 10E 9H 8G 5G 3C,8H 6G 8G 2G      Sorghum 9H 2C,9G 10E 10E 9H 3G 2G 0 9H 9H 2G 0 4C,9G 9H 7G 3G 3C,8G 2G 0      0 Sugar beet 9G 5G 5C,9G 9G 9G 2H 3G 0 9G 7G 4C,9G 7G 9C 9G 9C 5C,9G      2C,8G 8G 8G 5G Cotton 9G 8G 9G 9G 9G 2G 6G 0 8G 6G 2C,8G 9G 9G 9G 9G 9G      7G 4H 4G 0        Compound 11 Compound 12 Compound 13 Compound 14 Compound 15 Compound      16 Compound 17 Compound 18  Compound 19 Compound 20 Rate kg/ha 0.05 0.01 0      .05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01  0.05 0.01        POSTEMERGENCE Morningglory 2C,6G 0 10C 5C,9G 10C 10C 10C 5C,9G 10C      4C,9G 1C 0 3C,8H 3C,6G 3C,8G 2G 2C,2H 0 0 0 Cocklebur 4H 0 9C 9C 10C 9C      10C 9C 9C 3G 5G 0 9H 2H 3H 2H 2H 0 0 0 Velvetleaf 3H 0 10C 10C 10C 10C      9C 9C 10C 4C,9G 3C,8G 0 5C,9G 5C,9G 9C 2C,7H 0 0 0 0 Nutsedge 0 0 10C      6C,9G 2C,5G 2C,5G 4C,9G 3C,5G 4C,9G 5G 0 0 3C,6G 0 9G 0 0 0 0 0 Crabgrass       0 0 2C,5G 4G 0 0 2G 0 0 0 5G 0 2C,7G 3G 0 0 0 0 0 0 Giant Foxtail 0 0      9C 3C,7G 2G 0 2G 2G 2G 0 3G 0 7G 5G 3G 0 0 0 0 0 Barnyardgrass 0 0 9C      3C,9H 2H 0 4C,9H 3C,8H 3C,9H 5G 0 0 9H 3H 4H 0 0 0 0 0 Cheatgrass 0 0      5C,9G 5G 3G 0 8G 6G 4G 0 0 0 5G 3G 2G 0 0 0 0 0 Wild Oats 0 0 4G 0 0 0      2C,5G 0 0 0 0 0 6G 0 0 0 0 0 0 0 Wheat 0 0 2G 0 0 0 4G 0 0 0 0 0 2G 0 0      0 0 0 0 0 Corn 0 0 9G 2C,6H 3C,8H 0 3C,9H 2C,7G 3G 0 0 0 9G 3C,7H 2C,5H      5G 0 0 0 0 Barley 0 0 4G 2C,3G 0 0 2C,5G 0 0 0 0 0 3G 0 0 0 0 0 0 0      Soybean 2C,7G 0 9C 9C 9C 3C,9G 4C,9G 2C,8G 2H,4G 2G 1C 0 3C,8H 3C,3G      4C,9G 2C,5G 1C,1H 0 0 0 Rice 0 0 5C,9G 8G 8G 3G 9C 4C,9G 8G 4G 5G 0 8G      6G 9G 2G 2G 0 0 0 Sorghum 2G 0 4C,9H 4C,9H 2G 0 4C,9H 3C,7H 3C,9H 6G 4G      0 2C,8H 2C,4G 2C,2H 0 7G 0 0 0 Sugar beet 4C,9G 2C,6G 10C 9C 10C 10C 9C      9C 9C 9C 3C,7G 1H 3C,9H 3C,7G 5C,9G 2C,4G 7G 0 0 0 Cotton 3C,7G 3G 10C      9C 10C 9C 9C 4C,9G 9C 5C,9G 0 0 4C,9G 3C,8G 2C,5G 0 0 0 0 0 PREEMERGENCE M      orningglory 0 0 9G 3C,9G 9C 8G 9G 8G 9G 9C 0 0 3G 3G 8G 0 2G 0 0 0      Cocklebur 0 0 9H 8H -- 8H 9H -- 9H 5H 2H -- -- 2H 5G 0 2G 0 0 0 Velvetlea      f 0 0 9G 9G 4C,8G 3H 4C,9G 8G 9G 5H 0 0 2G 0 0 0 0 0 0 0 Nutsedge 0 0      10E 10E 2C 0 3C,7G 0 10E 0 0 0 5G 0 0 0 5G 0 0 0 Crabgrass 0 0 5G 2G 0 0      3G 0 0 0 0 0 5G 3G 0 0 2G 0 0 0 Giant Foxtail 0 0 6G 2G 0 0 3C,3H 0 0 0      0 0 7G 3G 0 0 2G 0 0 0 Barnyardgrass 0 0 3C,9H 3C,8H 0 0 4C,8H 3C,7G      3C,7H 0 0 0 5G 0 0 0 0 0 0 0 Cheatgrass 0 0 8G 7G 0 0 4C,9H 5G 0 0 0 0      3G 0 0 0 0 0 0 0 Wild Oats 0 0 5G 2C,4G 0 0 2C,9G 0 0 0 0 0 3G 0 2G 0 0      0 0 0 Wheat 0 0 3G 0 0 0 7G 0 0 0 0 0 0 0 0 0 0 0 0 0 Corn 0 0 3C,9H 7G      2C,8G 0 4C,9H 3C,7G 5G 0 0 0 2C,8G 2C,2G 2G 0 0 0 0 0 Barley 0 0 7G 6G 0      0 8G 4G 3G 0 0 0 0 0 0 0 0 0 0 0 Soybean 0 0 3C,8H 7H 8H 7H 3C,7H 3G 0 0      0 0 2C,5H 2C,2H 1C,5G 0 1C,1H 0 0 0 Rice 0 0 2C,9G 3C,8G 7G 0 3C,8H      3C,5G 2C,7G 0 5G 0 8G 4G 7G 0 6G 0 0 0 Sorghum 0 0 2C,9H 3C,8H 5G 0      3C,9H 3C,8H 3C,7G 2C,6G 3G 0 3C,6G 3G 2C,5G 0 2C,7G 0 0 0 Sugar beet 0 0      9C 9C 5C,9G 4C,9G 5C,9G 6G 4C,9G 8G 5G 0 5H 0 3H 0 0 0 0 0 Cotton 0 0 9G      9C 4C,9G 2C,8G 4C,9G 9G 9G 8G 0 0 2G 0 3G 0 2G 0 0 0        Compound 21 Compound 22 Compound 23 Compound 24 Compound 25 Compound      26 Compound 27 Compound 28  Compound 29 Compound 30 Rate kg/ha 0.05 0.01 0      .05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01   0.05 0.01        POSTEMERGENCE Morningglory 1C 1C 0 0 0 0 0 0 2G 0 4C,9H 3G 3C,8G 3H      10C 2C,6G 10C 5C,9G 2C,8G 1H Cocklebur 2C,5H 1H 0 0 0 0 0 0 2C,8G 6G 8H      2G 8H 1H 10C 5H 1H 6G 2C,9G 8G Velvetleaf 3C,9G 4G 0 0 0 0 0 0 10C 6G      6C,9G 10C 5C,9G 5G 10C 8G 10C 5C,9H 10C 2C,8G Nutsedge 0 0 0 0 0 0 0 0      7G 5G 8G 3C,8G 8G 7G 0 4G 4G 0 9G 2C,9G Crabgrass 0 0 0 0 0 0 0 0 4G 5G      4G 5G 3G 0 4G 0 0 0 3G 0 Giant Foxtail 0 0 0 0 0 0 1C 0 2G 4G 2C,5H      2C,6H 4G 0 2C,7G 0 2G 0 5G 0 Barnyardgrass 0 0 0 0 0 0 2H 0 9H 9H 4C,9H      7H 3H 0 3C,9H 5H 7H 0 6G 0 Cheatgrass 0 0 0 0 0 0 0 0 8G 7G 3G 6G 2G 0 0      0 0 0 7G 2G Wild Oats 0 0 0 0 0 0 3G 0 2C,7G 2C,3G 0 0 0 0 0 0 0 0 0 0      Wheat 0 0 0 0 0 0 3G 0 4G 0 0 2G 0 0 0 0 0 0 0 0 Corn 2C,8G 3G 0 0 0 0      3H 0 9G 5H 5G 1H 0 0 3C,9H 8H 3C,9H 0 0 0 Barley 0 0 0 0 0 0 5G 0 4C,9G      3C,7G 3G 0 0 0 0 0 0 0 0 0 Soybean 3C,7G 2H 3C,3H 0 0 0 1H 0 5C,9G 3C,6H      9C 5C,9G 5H 0 5C,9G 5C,9G 9C 4C,9G 2C,8H 2C,6H Rice 0 0 0 0 0 0 2C,7G 0      5C,9G 4C,9H 4G 3C,6G 8G 5G 5C,9G 5G 7G 2G 8G 3G Sorghum 2C 0 0 0 0 0      3C,7G 2C 9H 3C,9H 2G 2C 2C,3G 0 3C,9H 2G 2C,4H 0 1C,6G 0 Sugar beet      4C,9G 3C,6G 3C,7G 0 0 0 3C,7G 3G 10C 9H 9C 9C 9C 4C,9G 10C 9C 10C 9C 10C      9C Cotton 3C,6G 0 0 0 0 0 0 0 9C 3C,8H 9C 5C,9G 3C,8G 7G 9C 5C,9G 5C,9G      3C,7H 10C 10C PREEMERGENCE Morningglory 0 0 0 0 0 0 0 0 0 0 5G 3G 5G 3G      9G 5G 9G 5H 8G 5G Cocklebur 0 0 0 0 0 0 0 0 4G 0 8H -- 2H 0 -- 6H 4G 0      2C,7G 0 Velvetleaf 0 0 0 0 0 0 0 0 4C,9G 5H 5G 3H 5G 0 4C,9G 5G 3C,6G 1C      3G 2G Nutsedge 0 0 0 0 0 0 0 0 5G 0 9G 9G 10E 0 0 0 4G 0 9G 5G Crabgrass      0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4G 0 0 0 Giant Foxtail 0 0 0 0 0 0 0 0      2G 0 5G 0 0 0 3G 0 5G 0 7G 5G Barnyardgrass 0 0 0 0 0 0 0 0 9H 3C,8H      3C,9H 5G 3G 3G 3C,7G 0 3G 0 2C,6G 2G Cheatgrass 0 0 0 0 0 0 0 0 8G 7G 7G      0 2G 0 0 0 0 0 6G 4G Wild Oats 0 0 0 0 0 0 0 0 5G 3G 2G 0 0 0 0 0 2G 0 0      0 Wheat 0 0 0 0 0 0 0 0 6G 0 2G 0 0 0 0 0 0 0 0 0 Corn 0 0 0 0 0 0 2C,3G      0 3C,7G 3C,3H 2C,8G 3G 0 0 3C,8G 2C,7G 2C,7G 3G 1C 0 Barley 0 0 0 0 0 0      6G 0 8G 5G 1C 0 0 0 5G 0 0 0 0 0 Soybean 0 0 0 0 0 0 0 0 1H 1C 3C,7H      2C,2H 0 0 3C,9H 2C,5H 3C,7H 2C,2H 2G 0 Rice 0 0 0 0 0 0 4G 0 9H 9H 9H 5G      5G 4G 9H 6G 3C,8G 3G 2C,7G 0 Sorghum 0 0 0 0 0 0 3G 0 9H 9H 6G 0 5G 2G      3C,9G 3C,6G 2C,5G 1C 2C,6G 0 Sugar beet 0 0 0 0 0 0 3H 0 8G 3C,5H 9G 5G      7G 5G 9G 9G 2C,9G 3C,5H 8G 2C,6G Cotton 0 0 0 0 0 0 0 0 7G 2G 3G 2G 2G 0      2C,8G 8G 2C,9G 3H 6G 5G        Compound 31 Compound 32 Compound 33 Compound 34 CMPD 35 CMPD 36 CMPD      37 CMPD 38 CMPD 39  CMPD 40 Rate kg/ha 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01  0.05      0.01     POSTEMERGENCE Morningglory 3C,6G 4G 1H 0 3G 0 0 3G 0 0 3G 0 10C 1      0C 10C 10C 10C 10C 4C,8H 2G Cocklebur 3C,8H 3H 1H 0 5G 0 0 0 0 0 2G 0      10C 9C 10C 10C 10C 10C 10C 10C Velvetleaf 5C,9G 7H 1H 0 3C,8H 3C,6G      3C,6H 2H 0 0 5G 0 10C 9C 10C 10C 10C 10C 9C 9C Nutsedge 4C,9G 3C,7G      2C,6G 3G 0 0 0 0 0 0 0 0 9G 2C,5G 2C,9G 3C,8G 9C 9G 3C,3G 0 Crabgrass      3C,7G 6G 3G 0 0 0 0 0 0 0 0 0 2G 3G 3C,7G 2G 3G 0 5G 3C,5G Giant Foxtail      4C,9G 8G 2G 0 0 0 0 0 0 0 0 0 4C,8G 3C,6G 5C,9G 3C,8G 4C,9G 3C,7G 5C,9H      3C,7G Barnyardgrass 5C,9H 9H 3G 0 5C,9H 6G 5G 0 0 0 0 0 10C 9C 10C 9C 9C      9C 9C 3C,8H Cheatgrass 7G 2G 0 0 0 0 0 0 0 0 0 0 9C 3C,8G 9C 4C,9G 9C      4C,9G 4C,9G 5C,9G Wild Oats 3C,9G 3C,5G 0 0 0 0 0 0 0 0 0 0 4C,9G 3C,7G      3C,9G 2C,5G 3C,5G 0 3C,9G 4G Wheat 3C,6G 2G 0 0 0 0 0 0 0 0 0 0 9G 9G 9C      6G 3C,8G 6G 3C,9G 5G Corn 9H 9H 5H 0 2C,9H 6H 2H 0 0 0 3C,7G 0 3C,9H      3C,7H 4C,9G 2C,8H 4C,9G 2C,8H 2C,9G 3C,8H Barley 8G 3C,8G 0 0 0 0 0 0 0      0 0 0 9G 2C,5G 5C,8G 3C,8G 7G 2G 2C,8G 3G Soybean 3C,8H 3C,3H 2H 0 3C,4H      1H 3C,3H 1C,1H 0 0 3G 0 4C,9H 3C,7H 5C,9G 5C,9G 5C,9G 2C,8H 3C,8H 2H      Rice 5C,9G 4C,8H 3C,8G 3G 4G 2G 3G 0 0 0 0 0 4C,9G 4C,9G 5C,9G 3C,7G      5C,9G 5G 5C,9G 3C,8G Sorghum 4C,9G 4C,8G 3C,8G 3G 4C,7G 5G 2G 0 0 0      3C,5G 0 5C,9G 3C,9H 5C,9G 5C,9H 9C 4C,9G 5C,9G 3C,8H Sugar beet 4C,9G      4C,8H 3G 2G 3C,8H 3C,7G 3C,7G 4G 0 0 4C,3G 0 9C 9G 10C 10C 10C 10C 10C      4C,8H Cotton 4C,9H 3C,6G 0 0 2C,5G 2C,4G 3C,3H 2G 0 0 2C,3G 0 9C 9C 9C      5C,9G 9C 4C,9G 5C,9G 2C,3G PREEMERGENCE Morningglory 9G 8G 3H 0 0 0 3G 0 0       0 0 0 5G 8G 9G 8H 3H 2G 5G 0 Cocklebur 9H 9H 6G 0 0 0 -- 3G 0 0 0 0 9H      3C,2H 8H 3H 8H 3C,5H 7G 2G Velvetleaf 3C,9G 8G 5G 0 0 0 0 0 0 0 0 0      3C,8H 3C,6H 3C,8H 3C,7H 4C,8G 6H 4G 0 Nutsedge 3C,9G 3G 3C,8G 0 0 0 0 0      0 0 0 0 10E 0 2C,8G 10E 10E 9G 0 0 Crabgrass 6G 5G 0 0 0 0 0 0 0 0 0 0      4G 4G 3C,5G 3G 3G 0 0 0 Giant Foxtail 3C,8G 5G 0 0 0 0 0 0 0 0 0 0 3C,8H      2G 3C,7G 3C,6G 4C,9H 3C,6G 3G 0 Barnyardgrass 3C,9H 3C,7G 0 0 6G 0 5G 0      0 0 0 0 9H 3C,7G 1C,8H 3C,9H 9H 3C,7G 5G 0 Cheatgrass 6G 4G 0 0 0 0 0 0      0 0 0 0 9H 8G 5C,9G 5G 4C,9H 9G 4G 0 Wild Oats 2C,8G 3C,6G 0 0 0 0 0 0 0      0 0 0 3C,8H 3C,4G 3C,6G 3C,5G 3C,5G 1C 0 0 Wheat 7G 5G 0 0 0 0 0 0 0 0 0      0 3C,8H 0 2C,9G 4G 2C,8G 2G 0 0 Corn 3C,9H 2C,7G 0 0 3C,6G 2C,2G 4G 0 0      0 0 0 3C,9H 1C 9G 3C,3G 2C,9G 2C,8G 3C,6G 0 Barley 9G 8G 0 0 0 0 0 0 0 0      0 0 2C,8G 2G 3C,9H 0 2C,5G 0 0 0 Soybean 7H 7H 2H 0 0 0 2C 0 0 0 0 0      3C,7G 3C,3H 4C,6H 3C,6G 3C,6H 2C,5G 0 0 Rice 9H 9H 0 0 6G 0 1C 0 0 0 0 0      9H 3C,3H 4C,9H 3C,7G 9H 7G 4G 0 Sorghum 3C,9H 3C,9H 2C,5G 0 3C,9H 2G      2C,4G 0 0 0 0 0 10H 9H 10H 4C,9H 9H 3C,9G 3C,7G 2C Sugar beet 3C,9G      3C,8G 8G 4G 4G 4G 3H 3G 0 0 0 0 9C 9G 5C,9G 9C 5C,9G 10C 10C 7G Cotton      9G 9G 7G 0 2G 0 3G 0 0 0 0 0 2C,7H 2G 4C,8H 3G 2C,8G 7G 0 0        CMPD 41 CMPD 42 CMPD 43 CMPD 44 CMPD 45 CMPD 46 CMPD 47 CMPD 48 CMPD      49 CMPD 50 Rate kg/ha 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01  0.05 0.01        POSTEMERGENCE Morningglory 3C,8H 2C 10C 10C 10C 4C,8G 10C 10C 10C 10C      3C,5H 0 3C,5H 1H 10C 10C 10C 10C 10C  9C Cocklebur 10C 10C 10C 10C 10C      4C,8G 10C 9C 10C 10C 3C,6H 2H 3C,5H 2G 10C 9C 10C 10C 10C 10C Velvetleaf      4C,8H 3G 9C 3C,8H 10C 4C,9H 10C 9C 10C 9C 4C 1C 0 0 9C 2C,8G 10C 10C 10C      10C Nutsedge 2G 0 9G 3C,7G 3C,9G 2C,5G 2C,8G 2C,5G 3C,9G 3C,8G 2C 0 0 0      2C,9G 2C,5G 10C 4C,8G 4C,9G 4C,8G Crabgrass 2G 0 0 0 3C,5G 0 4G 0 4G 0      3C,6G 1C 6G 0 2G 0 2C,8G 4G 6G 5G Giant Foxtail 4C,9G 3C,7G 3C,8G 2C,5G      4C,8G 3C,4G 4C,9G 3C,7G 4C,9G 2C,6G 4C,9G 3C,7G 5C,9G 3C,6G 3C,8G 2C,5G      4C,9G 2C,8G 3C,9G 2C,9G Barnyardgrass 5C,9G 3C,7H 9C 10C 10C 9H 9C 9C 9C      5C,9H 9C 3C,9H 9C 3C,8H 9C 9C 10C 10C 9C 9C Cheatgrass 6C,9G 3C,7G 3C,7G      2C,4G 9C 3C,7G 5C,9G 6G 6C,9G 2C,8G 4C,8G 8G 5C,9G 7G 3C,8G 5G 10C 10C      10C 9C Wild Oats 2C,5G 2G 2G 0 3C,9G 3C,5G 2C,7G 2G 2C,5G 2G 3C,8G 2G      3C,6G 2G 2G 0 2C,9G 9G 7G 5G Wheat 9G 3C,9G 5G 0 2C,9G 7G 9G 3G 3C,8G      2C,7G 7G 3G 7G 8G 2G 0 3C,9G 4C,9G 3C,9G 2C,9G Corn 3C,9G 9G 3C,6H 1C,2G      3C,5H 2C,3G 3C,9H 3C,3G 9G 3C,9H 5C,9G 3C,9H 2C,9G 3C,8G 3C,5G 2G 3C,9G      2C,7H 2C,8H 3G Barley 9G 3C,7G 0 0 7G 0 3C,8G 3G 2C,8G 5G 7G 3G 2C,9G      3C,6G 3C,5G 0 5C,9G 3C,9G 3C,9G 7G Soybean 3C,4G 3C,3H 3C,8H 2C,4H 4C,9G      3C,8G 4C,9G 3C,8H 3C,9G 3C,9G 2G 0 2C,3G 0 3C,8G 2C,4H 6C,9G 5C,9G 6C,9G      6C,9G Rice 5C,9G 7G 4C,9G 2G 6C,9G 3C,9G 3C,9G 4G 4C,9G 7G 5C,9G 7G      4C,9G 7G 3C,7G 3G 9C 4C,9G 10C 3C,9G Sorghum 5C,9G 3C,8G 4C,9G 9G 3C,9G      3C,9H 3C,9G 3C,9H 5C,9G 4C,9G 4C,9G 3C,9G 5C,9H 3C,8H 4C,9G 9G 9C 9C 9C      3C,9G Sugar beet 10C 3C,7G 10C 9C 11G 11C 10C 10C 10C 10C 3C,8H 8G 3C,5H      0 10C 9C 9C 9C 9C 3C,9G Cotton 7G 0 5C,9G 10C 4C,9G 4C,9H 5C,9G 3C,9H 9C      4C,9G 3C,8H 0 0 0 9C 7G 10C 3C,9H 10C 3C,8G PREEMERGENCE Morningglory 0      0 8G 4C,9G 8G 2H 2G 1H 9G 5G 1C,1H 0 0 0 9G 7H 9H 9H 9H 7G Cocklebur 0 0      7H 3C,3H -- 5G 8H 0 -- -- 1H 0 -- 0 -- 3C,5H 3C,7H 3C,8H 9H 8H Velvetleaf       0 0 6G 2H 3C,7H 3C,4G 3C,8G 2C,2H 4C,9G 3C,7G 0 0 0 0 3C,7G 2C 3C,9G      3C,8G 6C,9G 3C,8G Nutsedge 0 0 10E 2C,5G 10E 3G 10E 6G 9G 5G 0 0 0 0 10E      6G 10E 10E 8G 3C,9G Crabgrass 0 0 0 0 4G 0 3G 0 3G 4G 0 0 0 0 0 0 3C,8G      3C,8G 2C,8G 3G Giant Foxtail 4G 0 3C,8G 3C,4G 3C,8H 3C,5G 3C,8G 5G 2C,9H      6G 3C,7G 0 0 0 3C,7G 3C,3G 9H 2C,7G 9H 5G Barnyardgrass 4G 0 3C,8H 3C,6H      9H 2C,5G 9H 2C,5G 9H 3C,7H 9H 0 3G 0 3C,9H 3C,7G 10H 9H 9H 9H Cheatgrass      6G 0 9G 6G 9H 8G 9G 7G 9H 8H 3G 0 0 0 8H 3G 10E 9H 9H 9G Wild Oats 1C 0      4G 0 3C,8H 2C,3G 3C,6G 2C 3C,6G 2G 2C 0 0 0 3G 0 2C,7G 7G 5G 4G Wheat 6G      0 5G 0 7H 1H 5G 0 6G 4G 3G 0 0 0 3G 0 8G 7G 2C,8G 4G Corn 3C,8G 0 8G      3C,5G 3C,7H 2C,2G 3C,9H 2C 3C,9G 3C,7G 3C,7G 0 2C,5G 0 3C,8G 3C,3G 3C,9H      3C,8H 2C,6H 0 Barley 6G 0 7G 0 9H 6G 3C,5G 5G 3C,7G 1C 2C,5G 0 0 0 3C,9G      3G 9G 8G 8G 0 Soybean 2G 0 3C,5H 3C,2H 3C,6H 2C,4G 3C,7G 2C,4H 3C,7G 4H      2H 0 0 0 3C,5H 2C,2H 4C,9G 3C,6G 3C,8G 2C,3G Rice 2C,5G 0 8H 3G 10E      3C,7G 8G 1C 9H 7G 8G 0 2C,5G 0 9H 2C,6G 10E 10E 3C,9H 3C,8G Sorghum      2C,7G 0 3C,9H 3C,8H 4C,9H 3C,7H 3C,9H 3C,9H 10E 3C,9H 3C,9H 0 3C,8G 0      4C,9H 3C,9H 10H 10H 5C,9H 4C,9H Sugar beet 9G 4G 9C 9C 9C 9C 5C,9G 9C      10C 4C,9G 5H 0 3H 0 9C 9G 4C,9G 9G 5C,9G 3C,8G Cotton 0 0 3C,8G 2G 7H 3G      3C,7G 3H 8G 5G 2G 0 0 0 3G 3G 9G 8G 2C,9G 2G        CMPD 51 CMPD 52 CMPD 53 CMPD 54 CMPD 55 CMPD 56 CMPD 57 CMPD 58 CMPD      59 CMPD 60 Rate kg/ha 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01  0.05 0.01        POSTEMERGENCE Morningglory 10C 10C 4C,8H 2C,3G 3C,5H 0 10C 10C 10C      3C,7G 10C 3C,7G 10C 10C 4C,8H 1C 4C,8H 1H 10C 4C,9G Cocklebur 10C 10C      4C,9H 3G 2C,4H 0 10C 10C 10C 9C 10C 9C 10C 10C 10C 4C,9H 10C 9C 10C 9C      Velvetleaf 10C 10C 2C 0 2C 0 10C 5C,9H 10C 9C 10C 9C 10C 10C 5C,9G 3C,7G      4C,8G 5G 10C 4C,9G Nutsedge 10C 10C 2C,8G 0 3G 0 10C 2C,7G 8G 0 8G 4G      3C,9G 8G 5G 0 0 0 6G 3G Crabgrass 6G 4G 3G 0 0 0 5G 5G 6G 2G 5G 2G 4G 0      5G 2C,3G 5G 2G 3G 0 Giant Foxtail 9C 9G 3C,9G 3C,8G 9C 6G 9G 7G 5C,9G      2C,6G 3C,9G 5G 4C,9G 5G 9C 2C,7G 5C,9G 2C,7G 7G 2G Barnyardgrass 9C 9C      9C 2C,8H 3C,5G 3C,7G 9C 9C 5C,9H 3C,7H 5C,9H 3C,8H 3C,9H 3C,8H 4C,9H      3C,8H 4C,9H 3C,7H 4C,9H 7H Cheatgrass 10C 9C 3C,9H 8G 3C,9G 8G 9C 9G      6C,9G 3C,9G 5C,9G 4C,9G 5C,9G 3C,6G 4C,8G 3C,7G 9C 3C,8G 8G 3C,5G Wild      Oats 4G 2G 4G 3G 2G 0 4G 2G 2C,9G 5G 9G 8G 7G 0 9G 2C,9G 3C,9G 8G 7G 4G      Wheat 3C,9G 2C,9G 4G 8G 7G 6G 9C 4G 9G 3G 9G 7G 8G 2G 9G 4G 9G 9G 7G 4G      Corn 4C,9G 9G 9C 9G 4C,8G 2C,8G 2G 2G 2C,8H 2G 3C,7H 2C,6G 3C,9H 7H      2C,6G 3G 3C,5G 0 3G 0 Barley 9G 5G 9G 9G 2C,3G 8G 9G 0 2C,8G 5G 8G 4G      3C,8G 5G 2C,8G 3C,5G 9G 8G 2C,5G 0 Soybean 5C,9G 4C,9G 4C,9H 2C,2G 2C 0      4C,9G 3C,9G 3C,7G 3H 3C,8H 2C,5G 4C,9G 3C,5G 2C,3G 3G 2C,3G 1H 3C,3H 2G      Rice 9C 2C,3G 9C 3C,9G 9C 6G 3C,8G 6G 5C,9G 3C,8G 4C,9G 2C,4G 4C,9G 8G      5C,9G 3C,4G 4C,9G 7G 8G 3G Sorghum 9C 9C 5C,9G 3C,8H 4C,9G 2C,5H 3C,9G      9G 3C,9G 3C,9G 4C,9G 3C,9H 3C,9G 3C,9G 4C,9G 4C,9H 5C,9G 5C,9G 3C,9G      3C,9H Sugar beet 9C 3C,9H 3C,6H 2C,3G 3C,7G 2C,3G 9C 9G 9C 9C 10C 9C 9C      9C 9C 9C 9C 3C,8H 9C 4C,9H Cotton 9C 10C 0 0 0 0 9C 5C,9G 9C 10C 10C 10C      5C,9G 10C 10C 7G 8G 7G 10C 7G PREEMERGENCE Morningglory 9H 9G 0 0 0 0 9G 9      G 9G 3G 2C,6G 0 9G 6H 5G  0 2G 0 7H 3C,3H Cocklebur -- 7G 0 0 0 0 8H 2C      -- 2C,5H 8H 2C,3G 8H 2C,3H -- -- 4G -- 8H 3C Velvetleaf 5C,9G 7G 0 0 0 0      3C,8H 2C 3C,8H 2C,5H 4C,9G 3C,3G 4C,8H 3G 3G 0 0 0 3C,6G 2G Nutsedge 9G      9G 10E 0 0 0 10E 9G 5G 0 2G 0 9G 10E 10E 0 0 0 0 0 Crabgrass 3C,9G 2G 2G      0 2G 0 2C,5G 0 0 0 5G 0 0 0 0 0 0 0 0 0 Giant Foxtail 3C,9H 3G 3C,9H 0      2C,8H 0 9H 5G 6G 2H 3C,7G 0 5G 0 3G 0 0 0 4G 0 Barnyardgrass 9H 9H 5G 0      3G 0 9H 9H 8H 3G 3C,8H 0 3C,8H 3G 3G 0 2G 0 3C,8H 4G Cheatgrass 3C,9G 9G      7G 0 3G 0 9H 8G 9H 5G 9G 0 9G 6G 0 0 0 0 3C,7G 3G Wild Oats 5G 3G 0 0 0      0 0 0 3C,7H 2C 3C,7G 0 2C,4G 0 5G 0 2C 0 3G 0 Wheat 9G 0 0 0 0 0 6G 0 3G      1C 7G 0 7G 2G 9G 0 2G 0 0 0 Corn 3C,8G 0 3C,7G 0 3C,6H 0 1C,4G 0 3C,8G 0      3C,7H 1C 3C,9G 2C,2G 3C,7G 0 2C,5G 0 2C,5G 2G Barley 8G 0 2C,3G 0 2C,6G      0 8G 0 9G 7G 9G 4G 7G 3G 9G 2G 3C,9G 0 2C,5G 2C,5G Soybean 2C,6G 5G 0 0      0 0 3C,6H 2C,4G 3C,5H 0 4C,6H 1C 3C,6H 3G 0 0 0 0 2C,2H 0 Rice 9H 9G      2C,7H 0 3G 0 10H 3C,9G 9H 4G 3C,7G 0 9H 7G 7G 0 4G 0 7G 4G Sorghum 10H      8G 9H 0 3C,8H 0 10H 3C,9H 9H 3C,7G 3C,9H 3C,7G 10H 3C,7H 3C,9H 3C,5G      3C,9H 0 3C,9H 3C,9H Sugar beet 3C,9G 8G 5G 0 5G 0 3C,9G 9G 9G 8G 9G 7G      9G 5C,9G 5H 0 5H 0 4C,9G 5H Cotton 9C 8G 0 0 0 0 3C,9G 2C,9G 9G 6G 3C,8H      3G 8G 4G 5G 0 4G 0 3C,6G 7G        CMPD 61 CMPD 62 CMPD 63 CMPD 64 CMPD 65 CMPD 66 CMPD 67 CMPD 68 CMPD      69 CMPD 70 Rate kg/ha 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01  0.05 0.01        POSTEMERGENCE Morningglory 10C 3C,8G 10C 10C 10C 3C,5G 4C,9H 3C,6H      3C,6H 0 -- 3C,7G 10C 3C,7H 10C 10C 10C 7G 4C,9H 2C,3H Cocklebur 10C      4C,9H 10C 10C 10C 10C 4C,9H 2C,2H 3C,8G 0 -- 4C,9H 9C 9C 10C 10C 10C 10C      4C,9H 2C,2G Velvetleaf 10C 9C 10C 10C 10C 9C 3C,5G 0 0 0 -- 3C,7G 9C      4C,9H 9C 9C 9C 5C,9H 3C,4H 0 Nutsedge 4C,9G 5G 4C,9G 5G 9C 3C,9G 4G 0 0      0 -- 0 9G 2G 8G 5G 3C,9G 2C,6G 3G 0 Crabgrass 5G 0 2G 0 5G 0 0 0 2C 0 --      0 2G 0 0 0 0 0 2G 0 Giant Foxtail 3C,8G 3C,6G 3C,9G 5G 3C,7G 4G 9C 3C,9G      5C,9G 2C,8G -- 0 3C,8G 4G 3C,8G 6G 3C,7G 3G 9C 3C,8G Barnyardgrass 9C 9C      9C 5C,9H 10C 9C 9C 5C,9G 9C 3C,8H -- 3C,7H 9C 3C,9H 9C 3C,8H 5C,9H 9C 9C      3C,8H Cheatgrass 9C 6C,9G 9C 2C,9G 9C 2C,8G 4C,9G 2C,9G 4C,9G 8G --      2C,6G 9C 9G 9C 9G 5C,9G 9G 9G 9G Wild Oats 3C,8G 2C 1C 0 2G 0 3C,3G 0      3C,5G 2C -- 0 4C,9G 3C,9G 4C,9G 3C,3G 4G 0 6C,9G 9G Wheat 9G 7G 3C,9G 8G      9G 5G 9C 5G 3C,9G 2C,8G -- 2G 9G 5G 5C,9G 3C,6G 6G 2G 9C 3C,7G Corn      4C,9H 2H 4C,9H 1H 2C,9G 7H 4C,9G 4C,9H 4C,9G 4C,9G -- 0 9H 3C,6H 3C,9G      4C,8H 9G 4C,9H 2C,9G 3C,6H Barley 4C,8G 4C,8G 4C,9G 2C,5G 3C,9H 5G 2C,8G      2C,6G 2C,9G 3C,9G -- 0 3C,9G 4G 2C,9G 3C,6G 8G 4G 3C,7G 2C Soybean 4C,9G      6H 3C,9G 3C,7G 3C,8H 3H 5G 0 3H 0 -- 0 3C,8H 5H 3C,8H 6H 3C,7G 3H 2H 0      Rice 9C 9C 9C 4C,9G 9C 4C,9G 9C 4C,9G 9C 2C,9G -- 4G 9C 5C,9G 4C,9G 5G      9C 3G 9C 9G Sorghum 9C 4C,9G 4C,9G 3C,9H 2C,9G 3C,9G 9C 4C,9G 5C,9G      4C,9G -- 3C,8G 9C 5C,9G 5C,9G 4C,9G 4C,9G 9G 4C,9G 4C,9G Sugar beet 10C      9C 10C 10C 9C 9C 4C,9H 2C,6H 3C,7H 2H -- 4C,8G 10C 9C 10C 9C 9C 10C      3C,8G 3C,7H Cotton 10C 9H 9C 3C,8G 10C 3C,9H 3C,7H 0 2H 0 -- 2G 3C,9H      4C,8H 10C 9H 5C,9G 2C,4G 7H 1C PREEMERGENCE Morningglory -- 8G 9G 9G 7G      2G 9G 0 0 0 -- 0 6G 2G 5G 2G 9G 2G 1C 0 Cocklebur 9H 9H 9H -- 9H 2C,5H      2C,3H 0 2H 0 -- -- 9H 8H 9H 7H -- 7H 2C,5H 0 Velvetleaf 7H 2G 4C,9G 7H      8H 3H 0 0 0 0 -- 0 3C,7H 3H 3C,8H 1H 8H 5H 0 0 Nutsedge 0 0 4C,9G 0 9G      8G 0 0 0 0 -- 0 0 0 0 0 4G 0 0 0 Crabgrass 0 0 3G 2G 2G 0 0 0 0 0 -- 0 0      0 2G 0 0 0 0 0 Giant Foxtail 5G 3G 8H 6G 8G 0 3C,9H 0 0 0 -- 0 6G 0      3C,5G 0 4G 0 0 0 Barnyardgrass 8H 5G 9H 3H 9H 9H 3C,8H 0 0 0 -- 0 8H 2H      9H 3G 9H 0 0 0 Cheatgrass 9G 6G 9G 9H 9H 8H 8G 0 0 0 -- 0 9H 6G 9H 7G 9G      6G 2C,6G 0 Wild Oats 3C,7G 3C,3G 3C,5G 0 0 0 1C 0 0 0 -- 0 9G 3C,6G      3C,6G 3C,3G 2C,4G 0 2C,7G 0 Wheat 8G 8G 3C,9H 6G 7G 3G 6G 0 0 0 -- 0 9G      3G 7G 3G 7G 0 2C,7G 0 Corn 3C,8G 0 3C,9H 0 3C,7G 0 3C,6G 2G 4G 0 -- 0      3C,6G 0 3C,8H 2G 3C,8G 2G 2C,7G 0 Barley 9G 8H 3C,9G 7G 9G 5G 2C,9G 3G      2C,9G 0 -- 0 8G 6G 9G 9G 9G 5G 2C,9G 9G Soybean 3C,7H 5H 3C,7H 3C,6H 7H      5G 0 0 0 0 -- 0 6G 2G 3C,7H 2C,4H 5H 5G 2H 0 Rice 9H 9H 9H 8G 9H 8H 9H      2G 0 0 -- 2G 9H 8H 8G 4G 8G 4G 9H 0 Sorghum 9H 9H 10H 2C,7G 9H 7G 3C,9H      3C,5G 2C,7G 0 -- 4G 9H 2C,9H 5C,9H 3C,8H 9H 3C,7G 9H 0 Sugar beet 9G 9G      9G 8G 9G 8G 3H 0 0 0 -- 3G 9G 7H 5C,9G 8H 9G 7H 2H 0 Cotton 3C,8G 1G 8H      7G 8G 9G 4G 0 0 0 -- 0 8G 2G 8H 0 8H 5G 0 0        CMPD 71 CMPD 72 CMPD 73 CMPD 74 CMPD 75 CMPD 76 CMPD 77 CMPD 78 CMPD      79 CMPD 80 Rate kg/ha 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01  0.05 0.01        POSTEMERGENCE Morningglory 9C 9C 3C,6H 3G 10C 5H 3C,8G 2C,2H 10C 1C,2G 9      C 4C,8G 9C 3C,8H 10C 2C,5G 2C,5G 0 4C,8H 2C,4H Cocklebur 10C 9C 3C,8H 1C      10C 3C,8H 10C 9C 10C 10C 10C 10C 10C 5C,9G 10C 10C 3C,7G 4G 5C,9G 4C,9G      Velvetleaf 9C 6G 0 0 10C 9C 9C 9C 10C 4C,9G 9C 5C,8H 9C 3C,7G 10C 4C,8G      4C,8G 2G 5C,9G 3C,7G Nutsedge 7G 2G 0 0 3C,8G 3C,7G 9C 3C,8G 4C,9G 3C,8G      2C,5G 2G 2C,5G 0 3C,8G 2C,6G 2C 0 3C,9G -- Crabgrass 0 0 6G 0 2G 0 3C,8G      0 5G 0 3C,5G 2C 2C 0 2G 0 0 0 0 0 Giant Foxtail 2C,6G 0 4C,9G 3C,7H      3C,5G 2C,3G 2C,5G 2G 3C,6G 2G 4C,9G 3C,6G 3C,7G 1C 2C,3G 1H 2G 0 1C 0      Barnyardgrass 5C,9G 2C,5H 5C,9H 3C,8H 4C,9H 3C,6G 9H 3C,9H 5C,9H 3C,7H      5C,9H 5C,9H 3C,8H 4G 3C,7H 1H 1C,2H 0 3H 3H Cheatgrass 8G 5G 4C,9G 9G      2C,8G 3C,7G 2C,7G 5G 3C,8G 8G 2C,9G 3G 2G 0 2C,5G 3G 0 0 2C,5G 2G Wild      Oats 2C,4G 0 9G 9G 2C,6G 3G 2C,6G 0 2C,2G 0 3C,6G 0 2C,3G 0 2G 0 0 0 0 0      Wheat 2G 0 9C 9G 8G 3G 8G 2G 5G 4G 3G 0 3G 0 2G 0 0 0 0 0 Corn 8H 0      4C,9G 3C,7G 2C,5H 2G 9H 7H 3C,9H 2C,6H 4C,9H 3C,7G 9G 3C,7H 2C,6G 2G 3G      0 2H 0 Barley 3G 0 4C,9G 3C,7G 3C,8G 2C,5G 2C,8G 7G 8G 2C,3H 2C,3G 0 0 0      2G 0 0 0 0 0 Soybean 3C,5H 0 2H 0 3C,8H 7H 5C,9G 4C,9G 5C,9G 4C,9G 3C,9H      3C,8G 5C,9G 3C,9H 3C,7H 2H 0 0 3C,6G 2C,2H Rice 8G 0 9C 9G 5C,9G 2C,9G      4C,9G 3C,8G 8G 8G 3C,8G 4G 3C,8G 3G 4G 2G 0 0 0 0 Sorghum 4C,9G 3C,9G 9C      4C,9G 5C,9G 3C,9G 2C,9G 3C,8H 4C,9H 4C,8G 9C 5C,9H 5C,9G 3C,9H 2C,9H      3C,8H 2C,5G 2C 3C,7G 2G Sugar beet 9G 5C,9G 4C,8H 3C,6H 10C 3C,8G 9C      3C,4G 9C 4C,8H 9C 5C,9G 9C 4C,6H 3C,7G 2C,2H 3C,4G 1C 3C,7G 2C,5G Cotton      9H 2G 0 0 5C,9G 4C,8H 9C 5C,9G 6C,9G 4C,9G 5C,9G 3C,8G 5C,9G 3C,8H 3C,9H      3C,9H -- 1C 4C,9G 3C,7H PREEMERGENCE Morningglory 9G 3G 3G 0 3C,8H 0 0 0 0       0 4G 1C 7H 2C,4G 9G 2H 0 0 0 0 Cocklebur 8H 3H 2C,3G 0 3C,4H 0 9H 3C,4H      3C,5H -- 8H 3C,7H 8H -- 9H 3C,3H 0 0 0 0 Velvetleaf 8H 2H 0 0 4C,9H 0 2H      3H 3C,7H 0 5H 2H 3C,5H 0 7H 2H 0 0 0 0 Nutsedge 0 0 0 0 9G 0 3C,8H 2C,5G      9G 0 4C,9G 3G 3C,9G 0 7G 2C,8G 0 0 0 0 Crabgrass 0 0 0 0 7G 0 5G 4G 5G 0      3C,7G 3C,6G 8G 0 9H 7G 0 0 0 0 Giant Foxtail 7H 0 2G 0 4C,8G 0 3C,6G 3G      3C,7G 0 9H 3C,7H 3C,7G 0 4G 0 0 0 0 0 Barnyardgrass 9H 3G 0 0 4C,9H      3C,6G 9H 3C,8H 9H 8H 9H 3C,6G 3C,9H 7G 3C,9H 8G 0 0 0 0 Cheatgrass 7G 5G      0 0 4C,9H 8G 9H 9G 9G 8G 9H 4G 3C,8G 0 9G 7G 0 0 0 0 Wild Oats 4G 0 0 0      3C,8H 3G 3C,6G 2G 2C,5G 2C,3G 3C,8H 0 3C,5G 0 3G 0 0 0 0 0 Wheat 3G 0 7G      0 8H 4G 6G 3G 7G 3G 5G 3C,5G 2C,5G 0 3G 2G 0 0 0 0 Corn 4G 0 4G 0 3C,9H      2G 2C,8G 2C,6G 3C,9H 2H,5G 3C,9H 3C,7G 9H 3C,7H 3C,7G 2C,5G 0 0 0 0      Barley 9G 3G 9G 5G 8G 4G 3C,5G 2C,5G 3C,4G 2G 3C,8G 3C,6G 7G 2G 5G 0 0 0      0 0 Soybean 5G 0 1C 0 3C,7H 2C,4H 3C,7G 2C,5G 3C,6H 2C,5G 3C,7H 3C,5G      4C,8H 3C,7G 3C,5H 2C,2H 0 0 0 0 Rice 8H 7G 7H 0 9H 3C,8G 9H 8G 9H 3C,7G      9H 7G 4C,9H 3C,7G 9G 7H 0 0 0 0 Sorghum 9H 3C,9H 3C,9H 0 2C,9H 3C,8H      3C,9G 3C,9H 9H 3C,7G 5C,9H 3C,9H 3C,9H 3C,9H 3C,9H 7G 3C 0 2C 0 Sugar      beet 9G 5H 0 0 10C 9G 4C,9G 4C,9G 9C 8H 5C,9G 9G 10C 9C 9C 5H 5G 0 5G 3H      Cotton 7G 0 0 0 7H 0 2C,4G 3G 5G 0 3G 0 3C,7H 2C,3G 2C,8G 3G 1H 0 0      0      CMPD 81 CMPD 82 CMPD 83 CMPD 84 CMPD 85 CMPD 86 CMPD 87 CMPD 88      Rate kg/ha 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01      0.05 0.01 0.05 0.01        POSTEMERGENCE Morningglory -- 2C,5G -- 0 1H 0 2C,4G 2H 0 0 1C,2G 0 0 0 0       0 Cocklebur -- 9C -- 5C,9G 5C,9H 3C,8G 4C,9G 2C,7G 0 0 1C 0 0 0 0 0      Velvetleaf -- 5C,9G -- 3C,7G 3G 0 1C 0 0 0 1C 0 0 0 0 0 Nutsedge -- 9G      -- 0 0 0 2C,8G -- 0 0 0 0 0 0 0 0 Crabgrass -- 0 -- 0 0 0 0 0 0 0 0 0 0      0 0 0 Giant Foxtail -- 3C,4H -- 3C,3G 1C 0 1C 0 0 0 0 0 0 0 0 0 Barnyardg      rass -- 0 -- 3C,4H 3C,6H 0 2H 0 0 0 0 0 0 0 0 0 Cheatgrass -- 0 -- 0 0 0      0 0 0 0 0 0 0 0 0 0 Wild Oats -- 0 -- 0 2G 0 0 0 0 0 0 0 0 0 0 0 Wheat      -- 0 -- 0 7G 0 0 0 0 0 0 0 0 0 0 0 Corn -- 0 -- 0 0 0 0 0 0 0 0 0 0 0 0      0 Barley -- 0 -- 0 0 0 0 0 0 0 0 0 0 0 0 0 Soybean -- 3C,7G -- 1H 4C,9G      2H 0 0 1C 0 1C 0 0 0 0 0 Rice -- 0 -- 0 0 0 0 0 0 0 0 0 0 0 0 0 Sorghum      -- 3C,8G -- 3C,7H 3C,9H 3C,8H 3C,4G 0 0 0 0 0 0 0 0 0 Sugar beet --      2C,5G -- 3G 3C,7G 2H 0 0 1C 0 2C,7G 0 0 0 0 0 Cotton -- 3C,7G -- 2G      3C,7G 2C,5G 2G 0 1C 0 1C 0 0 0 0 0 PREEMERGENCE Morningglory -- 0 -- 0 0 0       1C 0 0 0 0 0 0 0 0 0 Cocklebur -- 0 -- 0 -- 0 1C 0 -- 0 0 0 -- 0 0 0      Velvetleaf -- 0 -- 0 0 0 0 0 0 0 0 0 0 0 0 0 Nutsedge -- 0 -- 0 0 0 0 0      0 0 0 0 0 0 0 0 Crabgrass -- 0 -- 0 0 0 0 0 0 0 -- 0 0 0 0 0 Giant      Foxtail -- 0 -- 0 0 0 0 0 0 0 0 0 0 0 0 0 Barnyardgrass -- 0 -- 0 0 0 3G      0 0 0 0 0 0 0 0 0 Cheatgrass -- 0 -- 0 0 0 0 0 0 0 0 0 0 0 0 0 Wild Oats      -- 0 -- 0 0 0 0 0 0 0 0 0 0 0 0 0 Wheat -- 0 -- 0 0 0 0 0 0 0 0 0 0 0 0      0 Corn -- 1H -- 0 0 0 0 0 0 0 0 0 0 0 0 0 Barley -- 2G -- 0 0 0 0 0 0 0      0 0 0 0 0 0 Soybean -- 3C,2G -- 0 0 0 2C 0 0 0 0 0 0 0 0 0 Rice -- 2G --       0 0 0 0 0 0 0 0 0 0 0 0 0 Sorghum -- 3C,7G -- 0 2C,5G 0 2C,7G 0 7G 0 0      0 0 0 0 0 Sugar beet -- 7G -- 3G 3G 0 3G 0 0 0 7G 0 0 0 2G 0 Cotton --      1C -- 0 0 0 1C 0 3G 0 0 0 0 0 0 0

Test B Postemergence

Three round pans (25 cm diameter by 12.5 cm deep) were filled with Sassafras sandy loam soil. One pan was planted with nutsedge (Cyperus rotundus) tubers, crabgrass (Digitaria sanquinalis), sicklepod (Cassia obtusifolia), jimsonweed (Datura stramonium), velvetleaf (Abutilon theophrasti), lambsquarters (Chenopodium album), rice (Oryza sativa) and teaweed (Sida spinosa). The second pot was planted with green foxtail (Setaria viridis), cocklebur (Xantium pensylvanicum), moringglory (Ipomoea hederacea), cotton (Gossypium hirsutum), johnsongrass (Sorghum halepense), barnyardgrass (Echinochloa crusgalli), corn (Zea mays), soybean (Glycine max) and giant foxtail (Setaria faberi). The third pot was planed with wheat (Triticum aestivum), barley (Hordeum vulgare), wild buckwheat (Polgonum convolvulus L.), cheatgrass (Bromus secalinus L. ). sugarbeet (Beta vulgaris), wild oat (Avena fatua), viola (Viola arvensis), blackgrass (Alopecurus myosuroides), and rape (Brassica napus). The plants were grown for approximately fourteen days, then sprayed postemergence with the chemicals dissolved in a non-phytotoxic solvent.

Preemergence

Three round pans (25 cm diameter by 12.5 cm deep) were filled with Sassafras sandy loam soil. One pan was planted with nutsedge tubers, crabgrass, sicklepod, jimsonweed, velvetleaf, lambsquarters, rice and teaweed. The second pot was planted with green foxtail, cocklebur, morningglory, cotton, johnsongrass, barnyardgrass, corn, soybean and giant foxtail. The third pot was planted with wheat, barley, wild buckwheat, cheatgrass, sugarbeet, wild oat, viola, blackgrass and rape. The three pans were sprayed preemergence with the chemicals dissolved in a non-phytotoxic solvent.

Treated plants and controls were maintained in the greenhouse for 24 days, then all rated plants were compared to controls and visually rated for plant response.

Response ratings are based on a scale of 0 to 100 where 0=no effect and 100=complete control. A dash (-) response means no test.

Response ratings are contained in Table B.

    TABLE B       CMPD 55 CMPD 56 CMPD 57 CMPD 58 CMPD 59 CMPD 60 CMPD 61 RATE RATE =      G/HA 1. 4. 16. 62. 1. 4. 16. 62. 1. 4. 16. 62. 1. 4. 16. 62. 1. 4. 16.      62. 1. 4. 16. 62. 1. 4. 16. 62.        POSTEMERGENCE GIANT FOXTAIL 0 0 30 50 0 0 30 60 0 30 50 70 0 30 50 70      0 30 50 80 0 0 0 40 0 0 30 -- VELVETLEAF 50 70 100 100 30 50 70 100 70      100 100 100 30 50 70 100 0 30 60 100 30 60 90 100 30 80 100 100 SUGAR      BEETS 50 90 100 100 70 90 100 100 100 100 100 100 70 90 100 100 50 70 90      100 50 70 100 100 70 100 100 -- CRABGRASS 0 0 0 0 0 30 60 80 0 30 50 70      0 0 30 50 0 0 30 50 0 0 30 50 0 0 30 50 TEAWEED 0 20 30 60 0 30 50 70 0      30 50 70 0 0 30 50 0 0 30 50 0 0 30 60 0 0 30 50 JIMSONWEED 0 0 30 70 30      50 70 80 0 30 50 70 30 50 70 90 30 50 70 90 0 0 30 60 30 50 70 90 RICE 0      30 60 100 0 30 50 70 0 30 50 70 0 30 60 90 30 50 70 100 0 0 30 50 0 40      100 100 COCKLEBUR 60 90 100 100 50 70 100 100 70 80 100 100 50 70 100      100 50 70 100 100 50 70 90 100 30 50 70 100 COTTON 0 30 60 90 30 40 50      70 0 30 60 90 0 0 20 30 0 0 0 30 0 0 0 40 30 50 70 90 SOYBEAN 0 30 60      100 30 40 70 100 0 30 50 70 0 0 0 50 0 0 0 30 0 0 0 0 0 30 60 --      BARNYARD GRASS 0 30 60 90 0 30 60 100 0 30 50 80 30 50 70 90 0 30 50 70      0 30 40 70 30 60 90 100 WILD OATS 0 0 30 70 0 0 30 70 0 0 0 30 0 30 60      90 0 30 50 70 0 0 0 30 0 0 0 -- MORNINGGLORY 30 50 70 90 40 60 80 100 30      50 70 100 0 0 30 70 0 0 50 70 50 70 90 100 30 50 70 90 WHEAT 0 0 0 20 0      0 30 70 0 0 0 40 0 0 0 30 0 0 30 60 0 0 0 0 0 0 30 -- CASSIA 0 0 30 60 0      30 50 70 30 50 70 90 0 0 30 60 0 0 30 50 0 0 30 60 0 30 50 70 JOHNSONGRAS      S 30 50 70 90 0 30 60 90 30 50 70 90 30 60 90 100 0 30 60 90 0 30 40 70      30 60 90 100 NUTSEDGE 0 0 0 50 0 0 30 70 30 50 70 100 0 0 30 50 0 0 0 40      0 30 50 70 0 0 30 50 CORN 0 0 0 40 0 0 30 100 0 0 30 70 0 0 0 30 0 0 20      30 0 0 0 20 0 0 0 -- WILD BUCKWHEAT 0 30 60 100 30 50 70 90 30 50 70 90      0 0 0 30 0 0 0 40 0 30 50 70 30 50 70 -- BLACK GRASS 0 0 30 80 0 30 60      100 30 50 70 90 0 30 50 70 0 30 50 100 0 30 50 70 30 60 80 -- RAPESEED      60 100 100 100 70 100 100 100 90 100 100 100 70 90 100 100 60 80 100 100      50 90 100 100 100 100 100 -- BARLEY 0 0 0 40 0 0 30 70 0 0 20 40 0 0 30      50 0 0 30 70 0 0 0 30 0 0 30 -- GREEN FOXTAIL 0 0 30 50 0 0 30 60 0 30      50 70 0 30 50 70 0 30 50 80 0 0 30 60 0 0 30 60 CHEAT GRASS 0 30 50 70 0      30 50 90 30 50 70 100 0 0 30 60 0 0 30 70 0 0 30 60 30 50 70 -- VIOLA 0      30 60 80 30 50 70 100 70 90 100 100 30 50 70 90 30 50 70 100 30 50 70 90      30 50 70 -- LAMBSQUARTER 50 70 100 100 0 30 60 80 30 50 70 100 0 30 50      70 0 0 30 60 0 0 30 60 30 50 70 100 PREEMERGENCE GIANT FOXTAIL -- 0 30      60 -- 30 50 70 -- 30 50 70 -- 0 30 70 -- 0 30 60 -- 30 50 70 -- 0 30 60      VELVETLEAF -- 30 60 90 -- 0 30 80 -- 30 50 80 -- 0 30 50 -- 0 0 30 -- 0      30 60 -- 0 30 50 SUGAR BEETS -- 30 60 90 -- 30 60 100 -- 70 90 100 -- 50      70 90 -- 30 50 80 -- 50 70 90 -- 50 70 80 CRABGRASS -- 0 0 0 -- 30 50 70      -- 0 30 50 -- 0 0 30 -- 0 0 0 -- 0 0 0 -- 0 30 60 TEAWEED -- 0 40 70 --      0 30 60 -- 30 50 80 -- 30 50 70 -- 0 0 30 -- 0 0 30 -- 0 0 30 JIMSONWEED      -- 30 50 80 -- 30 50 70 -- 30 50 80 -- 30 60 100 -- 0 0 0 -- 0 0 30 -- 0      30 50 RICE -- 30 50 70 -- 0 30 80 -- 30 50 80 -- 0 30 60 -- 0 30 60 -- 0      30 50 -- 30 70 100 COCKLEBUR -- 30 60 100 -- 30 50 70 --  30 60 90 -- 0      0 0 -- 0 30 50 -- 30 50 70 -- 30 50 70 COTTON -- -- -- -- -- 0 0 30 -- 0      30 60 -- 0 0 20 -- 0 0 20 -- 0 0 30 -- 0 30 50 SOYBEAN -- 0 0 0 -- 0 0      20 -- 0 30 50 -- 0 0 0 -- 0 0 0 -- 0 0 0 -- 0 0 20 BARNYARD GRASS -- 30      60 90 -- 0 40 80 -- 30 50 80 -- 0 30 60 -- 0 30 60 -- 0 30 70 -- 0 30 60      WILD OATS -- 0 30 50 -- 0 20 40 -- 0 0 0 -- 0 0 30 -- 0 0 30 -- 0 0 0 --      0 0 30 MORNINGGLORY -- 0 40 70 -- 0 30 50 -- 0 30 60 -- 0 0 0 -- 0 0 30      --  0 30 70 -- 30 50 70 WHEAT -- 0 0 0 -- 0 0 30 -- 0 0 30 -- 0 0 30 --      0 30 50 -- 0 0 0 -- 0 30 50 CASSIA -- 0 30 60 -- 0 0 0 -- 30 50 70 -- 0      30 50 -- 0 0 0 -- 0 30 50 -- 0 30 50 JOHNSONGRASS -- 30 60 90 -- 30 50      80 -- 30 50 70 -- 0 30 80 -- 0 30 80 -- 30 50 70 -- 0 30 60 NUTSEDGE --      0 0 30 -- 0 30 50 -- 0 30 50 -- 50 70 100 -- 0 0 0 -- 0 40 80 -- 0 30 50      CORN -- 0 0 0 -- 0 0 0 -- 0 20 30 -- 0 0 0 -- 0 0 0 -- 0 0 0 -- 0 0 0      WILD BUCKWHEAT -- 30 50 70 -- 0 30 80 -- 50 70 100 -- 0 30 70 -- 0 30 60      -- 30 50 70 -- 60 70 80 BLACK GRASS -- 30 50 70 -- 30 60 100 -- 70 90      100 -- 0 40 80 -- 30 60 90 -- 50 70 90 -- 30 50 70 RAPESEED -- 30 70 90      -- 30 70 100 -- 50 70 100 -- 0 30 60 -- 0 30 70 -- 50 70 90 -- 50 70 80      BARLEY -- 0 0 0 -- 0 30 50 -- 0 0 30 -- 0 0 0 -- 0 0 0 -- 0 0 0 -- 0 30      50 GREEN FOXTAIL -- 0 30 60 -- 0 30 60 -- 30 50 70 -- 0 30 70 -- 0 30 50      -- 30 50 70 -- 30 50 70 CHEAT GRASS -- 30 50 70 -- 0 30 80 -- 50 70 90      -- 0 30 50 -- 30 50 80 --  30 50 80 -- 30 50 70 VIOLA -- 70 90 100 -- 70      90 100 -- 100 100 100 -- 100 100 100 -- 70 90 100 -- 90 100 100 -- 0 30      50 LAMBSQUARTER -- 30 60 100 -- 50 80 100 -- 50 100 100 -- 80 90 100 --      30 50 70 -- 50 70 100 -- 70 90 100        CMPD 62 CMPD 63 CMPD 67 CMPD 68 CMPD 69 CMPD 71 RATE RATE = G/HA 1. 4. 1      6. 62. 1. 4. 16. 62. 1. 4. 16. 62. 1. 4. 16. 62. 1. 4. 16. 62. 1. 4. 16. 6      2.        POSTEMERGENCE GIANT FOXTAIL 0 0 30 -- 0 0 30 -- 0 0 30 -- 0 0 30 -- 0      0 0 -- 0  0 0 -- VELVETLEAF 40 70 100 100 30 60 100 100 30 60 100 100 30      50 70 100 30 60 90 100 0 0 0 30 SUGAR BEETS 70 100 100 -- 50 70 80 --      100 100 100 -- 100 100 100 -- 70 100 100 -- 30 60 100 -- CRABGRASS 0 30      40 50 0 30 50 70 0 0 30 50 0 0 0 0 0 0 0 0 0 0 0 0 TEAWEED 0 20 40 60 0      0 30 60 0 30 50 70 0 0 30 50 0 0 30 50 0 0 0 0 JIMSONWEED 0 30 60 80 0 0      30 50 0 20 40 60 0 30 50 70 0 0 0 30 0 0 30 50 RICE 30 50 70 90 30 50 70      90 0 30 60 100 0 0 30 60 0 0 40 100 0 0 30 30 COCKLEBUR 30 50 70 100 70      100 100 100 30 50 70 90 50 70 100 100 30 50 70 100 30 50 70 100 COTTON 0      30 60 100 30 50 70 100 0 0 30 70 0 0 30 100 0 0 0 20 0 0 20 30 SOYBEAN 0      30 60 -- 0 0 40 -- 0 20 40 -- 0 30 50 -- 0 0 0 -- 0 0 0 -- BARNYARD      GRASS 30 50 70 100 30 50 70 100 30 50 70 90 30 50 70 100 30 50 70 100 0      0 30 60 WILD OATS 0 0 0 -- 0 0 0 -- 0 0 30 -- 0 0 0 -- 0 0 0 -- 0 0 0 --      MORNINGGLORY 0 30 50 70 0 30 50 70 30 50 70 90 30 50 70 90 0 0 30 60 30      50 70 80 WHEAT 0 0 30 -- 0 0 30 -- 0 0 0 -- 0 0 30 -- 0 0 0 -- 0 0 0 --      CASSIA 30 50 70 90 30 50 70 90 0 0 30 60 0 0 30 60 0 30 50 80 0 0 0 0      JOHNSONGRASS 0 30 60 100 0 30 60 100 30 50 70 100 30 50 70 100 0 0 30 70      0 0 30 60 NUTSEDGE 0 0 30 50 30 50 70 90 0 0 30 50 0 0 30 50 30 50 70      100 0 0 0 0 CORN 0 0 0 -- 0 0 0 -- 0 0 0 -- 0 0 30 -- 0 0 20 -- 0 0 0 --      WILD BUCKWHEAT 30 50 70 -- 30 50 70 -- 0 0 30 -- 0 30 50 -- 30 50 70 --      0 0 30 -- BLACK GRASS 30 50 70 -- 50 70 100 -- 0 30 60 -- 30 50 70 -- 30      60 90 -- 0 30 60 -- RAPESEED 100 100 100 -- 100 100 100 -- 70 90 100 --      70 100 100 -- 70 90 100 -- 30 70 100 -- BARLEY 0 0 0 -- 0 0 0 -- 0 0 0      -- 0 0 0 -- 0 0 0 --  0 0 0 -- GREEN FOXTAIL 0 0 30 60 0 0 30 50 0 0 30      50 0 0 30 50 0 0 0 30 0 0 0 0 CHEAT GRASS 30 50 70 -- 30 50 70 -- 30 50      70 -- 30 50 70 -- 30 50 70 -- 0 0 30 -- VIOLA 30 50 70 -- 50 70 100 --      30 50 70 -- 30 50 70 -- 50 70 90 -- 30 50 70 -- LAMBSQUARTER 30 60 90      100 30 50 70 90 30 60 100 100 30 50 70 100 30 60 90 100 0 0 30 50      PREEMERGENCE GIANT FOXTAIL -- 0 30 60 -- 0 30 60 -- 0 30 50 -- 30 50 70      -- 30 50 70 -- 30 50 70 VELVETLEAF -- 30 50 70 -- 0 30 50 -- 0 30 60 --      30 50 70 -- 30 50 70 -- 0 30 50 SUGAR BEETS -- 50 70 90 -- 50 70 80 --      30 50 70 -- 100 100 100 -- 60 70 80 -- 50 70 80 CRABGRASS -- 0 30 50 --      50 70 90 -- 0 30 50 -- 0 30 50 -- 0 0 0 -- 0 0 0 TEAWEED -- 30 50 70 --      0 30 50 -- 0 30 50 -- 0 30 60 -- 0 30 50 -- 0 0 30 JIMSONWEED -- 30 50      70 -- 0 30 50 -- 30 50 70 -- 30 50 70 -- 30 50 70 -- 0 30 50 RICE -- 30      60 100 -- 30 60 90 -- 30 60 90 -- 0 30 50 -- 30 50 70 -- 30 50 70      COCKLEBUR -- 30 50 70 -- 30 50 70 -- 30 50 70 -- 30 50 70 -- 50 70 100      -- 30 50 70 COTTON --  20 30 50 -- 0 20 30 -- 0 0 30 -- 0 30 50 -- 0 30      50 -- 0 0 30 SOYBEAN -- 0 30 50 -- 0 0 20 -- 0 0 20 -- 0 20 30 -- 0 0 0      -- 0 0 0 BARNYARD GRASS -- 30 60 90 -- 0 30 70 -- 0 30 60 -- 30 60 90 --      30 50 70 -- 30 50 70 WILD OATS -- 0 0 30 -- 0 0 0 -- 0 0 30 -- 20 40 60      -- 0 0 0 -- 0 0 30 MORNINGGLORY -- 30 50 70 -- 30 50 70 -- 30 50 70 -- 0      30 50 -- 30 50 70 -- 30 50 70 WHEAT -- 0 0 30 -- 0 0 30 -- 0 0 0 -- 0 0      30 -- 0 0 30 -- 0 0 0 CASSIA -- 30 50 70 -- 30 50 70 -- 0 0 30 -- 0 0 30      -- 0 0 30 -- 0 0 0 JOHNSONGRASS -- 30 50 70 -- 0 30 60 -- 30 50 70 -- 30      50 70 -- 30 50 70 -- 30 50 70 NUTSEDGE -- 0 30 50 -- 0 30 70 -- 0 30 50      -- 0 0 30 -- 0 30 60 -- 0 30 50 CORN -- 0 0 0 -- 0 0 30 -- 0 0 0 -- 0 0      20 -- 0 0 20 -- 0 0 0 WILD BUCKWHEAT -- 30 50 70 -- 30 50 70 -- 30 50 70      -- 50 70 80 -- 50 70 80 -- 30 50 70 BLACK GRASS -- 30 50 70 -- 50 70 90      -- 50 70 80 -- 100 100 100 -- 100 100 100 -- 60 80 90 RAPESEED -- 50 70      80 -- 70 80 90 -- 50 70 80 -- 50 70 90 -- 50 70 90 -- 50 70 80 BARLEY --      0 0 30 -- 0 0 30 -- 0 0 30 -- 0 0 30 -- 0 0 30 -- 0 0 0 GREEN FOXTAIL --      30 60 90 -- 30 60 90 -- 0 30 60 -- 30 60 100 -- 30 50 70 -- 30 50 70      CHEAT GRASS -- 30 50 70 -- 30 50 70 -- 30 50 70 -- 50 70 90 -- 30 50 70      -- 30 50 70 VIOLA -- 50 70 100 -- 50 70 100 -- 90 80 90 -- 100 100 100      -- 80 90 100 -- 50 70 90 LAMBSQUARTER -- 80 90 100 -- 70 90 100 -- 70 80      90 -- 90 100 100 -- 70 100 100 -- 30 70 100

Test C Procedure

Plastic trays were lined with polyethylene liners and filled with pasturized Sassafras loamy sand soil (pH 6.5, 1% OM). One tray was planted with wheat (Triticum aestivum), barley (Hordeum vulgare), wild oat (Avena fatua), cheatgrass (Bromus secalinus), blackgrass (Alopecurus myosuroides), annual bluegrass (Poa annua), green foxtail (Setaria viridis), Italian ryegrass (Lolium multiflorum), and rapeseed (Brassica napus). A second tray was planted with Matricaria inodora, cleavers bedstraw (Galium aparine), Russian thistle (Salsola kali), shepherdspurse (Capsella bursapastoris), kochia (Kochia scoparia), black nightshade (Solanum nigrum), speedwell (Veronica persica), wild buckwheat (Polygonum convolvulus), and sugarbeet (Beta vulgaris). For postemergence treatments, the first tray was planted 14 days before spraying, and the second tray was planted 24 days before treatment. Plants in the postemergence treatments ranged in height from 1 to 15 cm depending on specie. Wheat, barley, and wild oats were in the 2-leaf stage of development (Zadoks stage 11). A second set of trays was prepared in an identical manner before spraying to serve as preemergence treatments. Herbicides were diluted in a non-phytotoxic solvent and were applied to the trays using a belt sprayer.

Plants were grown in the greenhouse for 21 days at which time visual ratings were made by comparing to an untreated control planting. Ratings were based on a scale of 0=no effect to 100=complete kill. The results are in Table C.

                  TABLE C                                                          ______________________________________                                                      CMPD 69                                                           RATE KG/HA     0.004   0.008  0.016                                                                               0.032 0.064                                 ______________________________________                                         POSTEMERGENCE                                                                  WHEAT          10      30     40   60    90                                    BARLEY         0       10     20   50    50                                    WILD OATS      0        0      0    0    20                                    CHEATGRASS     0       20     40   70    90                                    BLACKGRASS     20      40     60   70    90                                    ANN. BLUEGRASS 0        0     10   20    40                                    GREEN FOXTAIL  0        0     20   40    60                                    ITAL. RYEGRASS 0        0      0    0    20                                    RAPESEED       100     100    100  100   100                                   WINTER WHEAT   0       20     30   50    70                                    WINTER BARLEY  0        0     30   50    70                                    GOATGRASS      0       10     20   30    40                                    WILD OATS STG 2                                                                               0        0      0    0    20                                    BLACKGRASS STG2                                                                               0       40     50   60    90                                    PREEMERGENCE                                                                   WHEAT          0       0       0   30    40                                    BARLEY         0       20     30   40    50                                    WILD OATS      0       0       0    0    20                                    CHEATGRASS     0       30     30   90    90                                    BLACKGRASS     0       20     50   60    80                                    ANN. BLUEGRASS 0       0      10   30    70                                    GREEN FOXTAIL  0       0       0   20    40                                    ITAL. RYEGRASS 0       0      10   20    30                                    RAPESEED       60      80     90   100   100                                   WINTER WHEAT   0       0      20   20    30                                    WINTER BARLEY  0       20     30   40    50                                    GOATGRASS      0       0       0   20    40                                    POSTEMERGENCE                                                                  GALIUM         10      50     50   70    70                                    WILD BUCKWHEAT 0        0     20   30    60                                    KOCHIA         0       10     20   30    70                                    FALSE CHAMOMILE                                                                               30      60     90   90    100                                   BLK. NIGHTSHADE                                                                               20      20     40   70    70                                    RUSSIAN THISTLE                                                                               50      60     80   90    90                                    SPEEDWELL      0        0     20   50    60                                    SUGARBEETS     80      100    100  100   100                                   VRNCA HDRAFOLIA                                                                               0       10     30   60    90                                    LAMBSQUARTER   0       20     40   100   100                                   FIELD PENNYCRES                                                                               40      70     90   90    90                                    VIOLA           0       0     20   50    50                                    PREEMERGENCE                                                                   GALIUM         0        0     20   50    50                                    WILD BUCKWHEAT 0        0     10   20    60                                    KOCHIA         0        0      0   20    70                                    FALSE CAMOMILE 20      60     70   70    90                                    BLK. NIGHTSHADE                                                                               10      20     50   70    70                                    RUSSIAN THISTLE                                                                               0        0      0   10    60                                    SPEEDWELL      0        0      0   40    40                                    SUGARBEETS     80      80     100  100   100                                   VRNCA HDRAFOLIA                                                                               0        0     30   50    70                                    LAMBSQUARTER   0       10     30   60    80                                    FIELD PENNYCRES                                                                               0       10     20   50    70                                    VIOLA          0       10     60   90    100                                   ______________________________________                                     

What is claimed is:
 1. A compound having the formula: ##STR133## wherein L is ##STR134## R is H or CH₃ ; W is O or S;R₁ is R₁ ' or R₁ "; R_(x) is H or halogen; R₁ ' is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, nitro, C₁ -C₃ alkoxy, CN, C₁ -C₃ haloalkoxy or C₁ -C₃ haloalkylthio; R₁ " is SO₂ NR_(a) R_(b), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, CO₂ R_(c) or C(O)NR_(g) R_(h) ; R_(a) is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy, ethoxy or C₃ -C₄ alkenyl; R_(b) is H or C₁ -C₃ alkyl; or R_(a) and R_(b) may be taken together to form (CH₂)₃, (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ; R_(c) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₃ cyanoalkyl, cyclopropylmethyl or C₂ -C₄ alkoxyalkyl; R_(g) is H or C₁ -C₃ alkyl; R_(h) is C₁ -C₃ alkyl; Q is Q₁ or Q₂ ; Q₁ is ER₂, NR₃ R₄, ##STR135## OSO₂ R₇, CN, SO₂ NHR₂₁, ##STR136## SO₂ NR₂₂ NR₂₃ R₂₄ or C₁ -C₄ alkyl substituted with R₈ ; E is O, S, SO or SO₂ ; W₁ is O or S; J is O, S, NH, NCH₃, CH₂ or a single bond; Q₂ is SO₂ NH₂, SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, halogen, CHO or CR_(p) ═NOR_(q) ; R_(i) is C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy, ethoxy or C₃ -C₄ alkenyl; R_(j) is C₁ -C₃ alkyl or R_(i) and R_(j) may be taken together to form (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ; R_(k) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₃ cyanoalkyl, cyclopropylmethyl or C₂ -C₄ alkoxyalkyl; R_(m) is H or C₁ -C₃ alkyl; R_(n) is C₁ -C₃ alkyl; R_(p) is H, C₁ -C₄ alkyl or C₁ -C₄ haloalkyl; R_(q) is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl; R₂ is C₁ -C₆ alkyl substituted with R₈, C₂ -C₆ alkenyl substituted with R₈, C₃ -C₆ alkynyl, C₃ -C₆ alkynyl substituted with R₈, C₁ -C₆ haloalkyl, C₂ -C₆ haloalkenyl or C₃ -C₆ haloalkynyl; R₃ is C₁ -C₄ alkyl; R₄ is H or C₁ -C₄ alkyl; or R₃ and R₄ may be taken together to form (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ; R₅ and R₆ are independently C₁ -C₂ alkyl, C₁ -C₂ alkoxy, C₁ -C₂ alkylthio, C₁ -C₂ alkylamino or di(C₁ -C₂ alkyl)amino; R₇ is C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₃ -C₄ alkenyl, C₃ -C₄ haloalkenyl, C₃ -C₄ alkynyl, C₃ -C₄ haloalkynyl or NR₁₉ R₂₀ ; R₈ is OR₉, S(O)_(n) R₁₀, CO₂ R₁₀, SO₂ NR₁₁ R₁₂, NR₁₁ R₁₂, CONR₁₁ R₁₂, C(O)R₁₃, ##STR137## CN, SCN, SH, NO₂ or N₃ ; R₉ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₁ -C₄ haloalkyl, C₃ -C₄ haloalkenyl, C₃ -C₄ haloalkynyl, C₂ -C₄ alkylcarbonyl, C₁ -C₄ alkylsulfonyl, C₂ -C₄ alkoxyalkyl, C₂ -C₄ alkylthioalkyl or C₂ -C₄ cyanoalkyl; R₁₀ is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₁ -C₄ haloalkyl, C₃ -C₄ haloalkenyl, C₃ -C₄ haloalkynyl, C₂ -C₄ alkoxyalkyl, C₂ -C₄ alkylthioalkyl or C₂ -C₄ cyanoalkyl; R₁₁ is H or C₁ -C₃ alkyl; R₁₂ is H, C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₃ -C₆ cycloalkyl, C₂ -C₄ alkoxyalkyl, C₂ -C₄ alkylthioalkyl, C₂ -C₄ cyanoalkyl, C₁ -C₃ alkoxy, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl; or R₁₁ and R₁₂ may be taken together to form (CH₂)₃, (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ; R₁₃ is H, C₁ -C₄ alkyl or C₁ -C₄ haloalkyl; R₁₄ is C₁ -C₂ alkyl; R₁₅ is H or CH₃ ; R₁₆ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl; R₁₇ is C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ alkylthio, C₁ -C₄ alkylamino or di(C₁ -C₄ alkyl)amino; R₁₉ is H, C₁ -C₃ alkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl; R₂₀ is H or C₁ -C₃ alkyl; or R₁₉ and R₂₀ may be taken together to form (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ; R₂₁ is C₁ -C₄ alkyl, C₁ -C₃ haloalkyl, C₂ -C₃ cyanoalkyl, cyclopropyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ alkoxyalkyl or C₁ -C₂ alkoxy; R₂₂ is H or C₁ -C₄ alkyl; R₂₃ is H or C₁ -C₄ alkyl; R₂₄ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₁ -C₄ haloalkyl or phenyl which may be optionally substituted with R₂₅ ; or R₂₃ and R₂₄ may be taken together to form (CH₂)₄, (CH₂)₅ or CH₂ CH₂ OCH₂ CH₂ ; R₂₅ is H, CH₃, Cl, F, Br, NO₂, CF₃, CN or OCH₃ ; m is 1 or 2; n is 0, 1 or 2; W₂ and W₃ are independently O or S; A is ##STR138## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃ alkyl)amino; Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₄ -C₅ cycloalkyl, C₂ -C₄ alkynyl, cyano, ##STR139## or N(OCH₃)CH₃ ; q is 2 or 3; L₁ and L₂ are independently O or S; R_(d) and R_(e) are independently C₁ -C₂ alkyl; R_(f) is H or CH₃ ; Z is CH;and their agriculturally suitable salts; provided that (a) when X is Cl, F, Br or I, then Y is OCH₃, OC₂ H₅, N(OCH₃)CH₃, NHCH₃ ', N(CH₃)₂ or OCF₂ H; (b) when E is O or S and R₉ is H, then R₂ is other than CH₂ OR₉ ; (c) when W is S, then R is H and Y is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃, CH(OCH₃)₂ or ##STR140## (d) the total number of carbon atoms in R₁ and Q is less than or equal to 10; (e) when Q₁ is ##STR141## then X and Y are other than OCF₂ H or SCF₂ H; (f) when R₁ is R₁ ' then L is L-1, L-3, L-5, L-6, L-8 or L-10; (g) the total number of carbon atoms in R₂₂, R₂₃ and R₂₄ is less than or equal to 10; (h) when R₂₁ is C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, C₁ -C₂ alkoxy or C₃ -C₄ alkenyl, then X and Y are other than OCF₂ H or SCF₂ H; (i) when Y is CN and R₁ ' is H, F, Cl or CH₃, then R₂₁ is other than C₁ -C₃ alkyl; (j) when R₁ is R₁ ' then Q is Q₁ ; (k) when R₁ is R₁ " then Q is Q₁ or Q₂ ; (l) when Q₂ is halogen then R_(x) is halogen; (m) when R₁ " is SO₂ NR_(a) R_(b), CO₂ R_(c) or C(O)NR_(g) R_(h) when Q is SO₂ NHR₂₁, ##STR142## SO₂ NR₂₂ NR₂₃ R₂₄, SO₂ NH₂, SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n) or CHO then L is L-1, L-2, L-5 or L-6; and (n) when Q₂ is halogen then L is L-2, L-4, L-5, L-6, L-7 or L-9.
 2. A compound of claim 1 wherein Q is Q₁.
 3. A compound of claim 1 whereinR is R₁ '; R₁ ' is H, CH₃, Cl, Br, OCH₃ or C₁ haloalkyl; X is CH₃, OCH₃, OCH₂ CH₃, Cl, F, Br, I, OCF₂ H, CH₂ F, CF₃, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl or CH₂ Br; and Y is H, CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CH₂ CH₃, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OCH₂ CH₃, OCH₂ CH₂ OCH₃, CH₂ SCH₃, CH₂ SCH₂ CH₃, OCH₂ CH₂ OCH₃, ##STR143## OCF₂ H, SCF₂ H, C.tbd.CH or C.tbd.CCH₃.
 4. A compound of claim 3 where W is O.
 5. A compound of claim 4 where L is L-1 or L-3.
 6. A compound of claim 4 where L is L-5, L-6, L-8 or L-10.
 7. A compound of claim 5 whereQ₁ is ER₂, ##STR144## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR145## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ aalkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 8. A compound of claim 7 whereX is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂ ; Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; and R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃.
 9. A compound of claim 6 whereQ₁ is ER₂, ##STR146## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR147## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 10. A compound of claim 9 whereX is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂ ; Q₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; and R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃.
 11. A compound of claim 1 whereinR₁ is R₁ "; X is CH₃, OCH₃, OCH₂ CH₃, Cl, F, Br, I, OCF₂ H, CH₂ F, CF₃, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl or CH₂ Br; and Y is H, CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CH₂ CH₃, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OCH₂ CH₃, OCH₂ CH₂ OCH₃, CH₂ SCH₃, CH₂ SCH₂ CH₃, OCH₂ CH₂ OCH₃, ##STR148## OCF₂ H, SCF₂ H, C.tbd.CH or C.tbd.CCH₃.
 12. A compound of claim 11 where W is O.
 13. A compound of claim 12 where L is L-1.
 14. A compound of claim 12 where L is L-2.
 15. A compound of claim 12 where L is L-3.
 16. A compound of claim 12 where L is L-4.
 17. A compound of claim 12 where L is L-5.
 18. A compound of claim 12 where L is L-6.
 19. A compound of claim 12 where L is L-7.
 20. A compound of claim 12 where L is L-8.
 21. A compound of claim 12 where L is L-9.
 22. A compound of claim 12 where L is L-10.
 23. A compound of claim 13 whereQ₁ is ER₂, ##STR149## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR150## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 24. A compound of claim 23 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 25. A compound of claim 24 whereX is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 26. A compound of claim 14 whereQ₁ is ER₂, ##STR151## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR152## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 27. A compound of claim 26 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 28. A compound of claim 27 whereA is A-1; X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 29. A compound of claim 15 whereQ₁ is ER₂, ##STR153## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR154## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 30. A compound of claim 29 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 31. A compound of claim 30 whereX is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 32. A compound of claim 16 whereQ₁ is ER₂, ##STR155## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR156## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 33. A compound of claim 32 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 34. A compound of claim 33 whereA is A-1; X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 35. A compound of claim 17 whereQ₁ is ER₂, ##STR157## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR158## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃, or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 36. A compound of claim 35 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 37. A compound of claim 36 where;X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 38. A compound of claim 18 whereQ₁ is ER₂, ##STR159## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR160## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 39. A compound of claim 38 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 40. A compound of claim 39 whereX is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 41. A compound of claim 19 whereQ₁ is ER₂, ##STR161## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR162## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 42. A compound of claim 41 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or So₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -CH₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 43. A compound of claim 42 whereinX is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 44. A compound of claim 20 where Q₁ is ER₂, ##STR163## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR164## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl;R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 45. A compound of claim 44 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 46. A compound of claim 45 whereX is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 47. A compound of claim 21 whereQ₁ is ER₂, ##STR165## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR166## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 48. A compound of claim 47 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 49. A compound of claim 48 whereX is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 50. A compound of claim 22 whereQ₁ is ER₂, ##STR167## C₁ -C₂ alkyl substituted with R₈, CN, SO₂ NHC₁ -C₂ alkyl, SO₂ NHcyclopropyl or ##STR168## R₂ is C₁ -C₃ alkyl substituted with R₈, C₁ -C₃ haloalkyl, C₂ -C₃ haloalkenyl or C₃ -C₄ alkynyl; R₅ and R₆ are independently CH₃, OCH₃ or SCH₃ ; R₈ is OR₉, C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl, C₁ -C₂ alkylsulfonyl, CO₂ (C₁ -C₂ alkyl), SO₂ N(C₁ -C₂ alkyl)₂, C(O)CH₃, CN or C(O)N(CH₃)₂ ; and R₉ is H, C₁ -C₂ alkyl or C₂ -C₃ cyanoalkyl.
 51. A compound of claim 50 whereQ₁ is ER₂, C₁ -C₂ alkyl substituted with R₈, CN or SO₂ NHC₁ -C₂ alkyl; E is S or SO₂ ; R₂ is C₁ -C₂ alkyl substituted with R₈ or C₁ -C₂ haloalkyl; R₈ is CH₃ O, CH₃ CH₂ O, CH₃ S, CH₃ SO₂, SO₂ N(CH₃)₂ or CO₂ CH₃ ; Q₂ is SO₂ NR_(i) R_(j), CO₂ R_(k), C(O)NR_(m) R_(n), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl or C₁ -C₃ alkylsulfonyl; R_(a) is H or C₁ -C₂ alkyl; R_(b) is C₁ -C₂ alkyl; R_(c) and R_(k) are independently C₁ -C₃ alkyl, allyl, CH₂ CH₂ Cl or CH₂ CH₂ OCH₃ ; R_(g) is H or C₁ -C₂ alkyl; R_(h) is CH₃ ; R_(i) is C₁ -C₂ alkyl; and R_(j) is C₁ -C₂ alkyl.
 52. A compound of claim 51 where;X is CH₃, OCH₃, OCH₂ CH₃, Cl, OCF₂ H or OCH₂ CF₃ ; and Y is CH₃, OCH₃, C₂ H₅, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.
 53. The compound of claim 1 which is N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(methoxymethyl)-3-thiophenesulfonamide.
 54. The compound of claim 1 which is N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-4-cyano-3-thiophenesulfonamide.
 55. The compound of claim 1 which is N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(2-methoxyethyl)-2-thiophenesulfonamide.
 56. The compound of claim 1 which is 3-[[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-4-(propylsulfinyl)-2-thiophenecarboxylic acid, methyl ester.
 57. The compound of claim 1 which is 3-[[(4-methoxy-6-methyl-pyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-4-(propylsulfinyl)-2-thiophenecarboxylic acid, methyl ester.
 58. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 1 and at least one of the following: surfactant, solid or liquid diluent.
 59. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 2 and at least one of the following: surfactant, solid or liquid diluent.
 60. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 3 and at least one of the following: surfactant, solid or liquid diluent.
 61. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 4 and at least one of the following: surfactant, solid or liquid diluent.
 62. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 5 and at least one of the following: surfactant, solid or liquid diluent.
 63. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 6 and at least one of the following: surfactant, solid or liquid diluent.
 64. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 7 and at least one of the following: surfactant, solid or liquid diluent.
 65. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 8 and at least one of the following: surfactant, solid or liquid diluent.
 66. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 9 and at least one of the following: surfactant, solid or liquid diluent.
 67. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 10 and at least one of the following: surfactant, solid or liquid diluent.
 68. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 11 and at least one of the following: surfactant, solid or liquid diluent.
 69. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 53 and at least one of the following: surfactant, solid or liquid diluent.
 70. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 54 and at least one of the following: surfactant, solid or liquid diluent.
 71. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 55 and at least one of the following: surfactant, solid or liquid diluent.
 72. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 56 and at least one of the following: surfactant, solid or liquid diluent.
 73. A composition suitable for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 57 and at least one of the following: surfactant, solid or liquid diluent.
 74. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 1. 75. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 2. 76. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 3. 77. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 4. 78. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 5. 79. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 6. 80. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 7. 81. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 8. 82. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 9. 83. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 10. 84. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 11. 85. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 53. 86. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 54. 87. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 55. 88. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 58. 89. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 59. 